Jiaxi Shi

ORCID: 0009-0001-8428-4738
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About
Contact & Profiles
Research Areas
  • Platelet Disorders and Treatments
  • Gastrointestinal Bleeding Diagnosis and Treatment
  • Autophagy in Disease and Therapy
  • Bone Metabolism and Diseases
  • TGF-β signaling in diseases
  • Liver Disease Diagnosis and Treatment
  • Inflammasome and immune disorders
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Bone health and treatments
  • Acute Myocardial Infarction Research
  • Pharmacological Effects of Natural Compounds
  • Cardiovascular Function and Risk Factors
  • Autoimmune Bullous Skin Diseases
  • Plant-based Medicinal Research
  • Diet, Metabolism, and Disease
  • Heart Failure Treatment and Management
  • Traditional Chinese Medicine Analysis

Guangzhou University of Chinese Medicine
2018-2024

Atherosclerosis (AS) is a major cause of mortality worldwide. Geniposide (GP) has lipolytic and anti-inflammatory effects widely administered for the treatment cardiovascular disease. There considerable evidence importance autophagy in system, GP can promote improve AS. However, underlying mechanism still unclear; network pharmacology molecular docking suggest that may play anti-atherosclerotic roles by regulating PI3K/Akt/mTOR pathway, which typical signal transduction approach. We further...

10.1142/s0192415x24500940 article EN The American Journal of Chinese Medicine 2024-01-01

Heart failure (HF), manifested as a severe or end stage of various cardiac diseases, is characterized by increased incidence, mortality, re-hospitalization, and economic burden. Myocardial infarction (MI) one the most common important causes HF. Since 2005, acute MI (AMI)-associated mortality in China has been on rise, accounts for 23.1% Traditional Chinese medicine (TCM) unique advantages controlling angina pectoris HF symptoms, improving patients' quality life. Compound Xueshuantong...

10.1097/md.0000000000032311 article EN cc-by-nc Medicine 2022-12-16

Abstract Background Heyde’s syndrome can be easily overlooked or misjudged in clinical practice because it shares common manifestations with multiple diseases as well limited accuracy of several corresponding examinations for diagnosing triad. Moreover, aortic valve replacement is often delayed these patients due to the contradiction between anticoagulation and hemostasis. Herein, we present a rare case atypical syndrome. The patient’s severe intermittent gastrointestinal bleeding was not...

10.1186/s13019-023-02337-8 article EN cc-by Journal of Cardiothoracic Surgery 2023-07-10

Abstract Background: Heyde’s syndrome can be easily overlooked or misjudged in clinical practice because it shares common manifestations with multiple diseases and of the limited accuracy corresponding examinations for diagnosing triad. Moreover, aortic valve replacement is often delayed these patients contradiction between anticoagulation haemostasis. Herein, we present a rare case atypical Heyde's syndrome. The patient's severe intermittent gastrointestinal bleeding was not completely...

10.21203/rs.3.rs-1412091/v1 preprint EN cc-by Research Square (Research Square) 2022-03-08
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