- Lung Cancer Diagnosis and Treatment
- Pleural and Pulmonary Diseases
- Tracheal and airway disorders
- Ultrasound in Clinical Applications
- Esophageal and GI Pathology
- Airway Management and Intubation Techniques
- Thyroid Cancer Diagnosis and Treatment
- Immune cells in cancer
- Cancer-related Molecular Pathways
- Immune Response and Inflammation
- Radiomics and Machine Learning in Medical Imaging
- interferon and immune responses
- Salivary Gland Tumors Diagnosis and Treatment
- Ear and Head Tumors
- Congenital Diaphragmatic Hernia Studies
- Tumors and Oncological Cases
Trinity College Dublin
2025
University of Campania "Luigi Vanvitelli"
2022-2024
The cytokine interleukin-10 (IL-10) limits the immune response and promotes resolution of acute inflammation. Because its immunosuppressive effects, IL-10 up-regulation is a common feature tumor progression metastasis. Recently, regulation has been shown to depend on mitochondria redox-sensitive signals. We have found that Suppressor site III Qo Electron Leak 1.2 (S3QEL 1.2), specific inhibitor reactive oxygen species (ROS) production from mitochondrial complex III, myxothiazol, inhibitor,...
Salivary gland carcinomas (SGCs) are rare neoplasms, representing less than 10% of all head and neck tumors, but they extremely heterogeneous from the histological point view, their clinical behavior, genetics. The guidelines regarding treatment include surgery in most cases, which can also play an important role oligometastatic disease. Where cannot be used, systemic therapy comes into play. Systemic for many years has been represented by polychemotherapy, recently, with affirmation...
Video-assisted thoracic surgery (VATS) for ipsilateral reoperations is controversial, because after the first surgical intervention, pleural adhesions occur frequently in cavity and/or chest wall. This study assessed usefulness of preoperative ultrasonography to reduce incidence lung injury at time initial port insertion during secondary VATS.This was a retrospective, single-center study. Nine patients who underwent Vanvitelli Hospitalfrom September 2019 February 2022, were scheduled second...
Abstract Background Video‐assisted thoracoscopic surgery (VATS) resection of deep‐seated lung nodules smaller than 1 cm is extremely challenging. Several methods have been proposed to overcome this limitation but with not neglectable complications. Intraoperative ultrasound (ILU) the latest minimally invasive technique. The aim current study was analyze accuracy and efficacy ILU associated VATS visualize solitary pulmonary cm. Methods Patients subcentimetric were included in retrospective...
Staging of the mediastinum lymph nodes involvement in patients with non-small cell lung cancer (NSCLC) is an important prognostic factor determining most appropriate multimodality treatment plan. The objective this study to assess ultrasound characteristics mediastinal metastasis and effectiveness intraoperative ultrasound-guided nodal dissection resected NSCLC.All undergoing video-assisted thoracoscopic surgery lobectomy pulmonary lymphadenectomy from November 2020 March 2022 at thoracic...
Abstract Introduction Benign tracheobronchial stenosis is a abnormal tracheal lumen narrowing that may incur progressive dyspnea and life-threatening hypoxemia. There no consensus on which patients should be treated with endoscopic or surgical method. This study investigates the outcomes of bronchoscopic dilatation in treatment benign using device equipped blade to cut stenotic lesions dense fibrosis. Materials methods The procedure was carried out an operating room under general anesthesia....
Abstract INTRODUCTION Benign tracheobronchial stenosis is a abnormal tracheal lumen narrowing that may incur progressive dyspnea and life-threatening hypoxemia. There no consensus on which patients should be treated with endoscopic or surgical method. This study investigates the outcomes bronchoscopic dilatation for treating benign using device equipped blade to cut stenotic lesions dense fibrosis. MATERIALS AND METHODS The procedure was carried out in an operating room under general...
Abstract OBJECTIVE Video-Assisted Thoracic Surgery (VATS) resection, of deep-seated and nodules smaller than 3 cm, is very hard.Solitary, small pulmonary are difficult to palpate or see during VATS. We aimed evaluated the validity Intraoperative lung ultrasound (ILU) visualize solitary cm enhance knowledge on morphological patterns. RESULTS US processor was inserted by expert surgeon into chest through operating hole, mediastinal, costal diaphragmatic surfaces were explored.VATS- Ultrasound...