A5100334495- RNA Interference and Gene Delivery
- Cancer Mechanisms and Therapy
- Multiple Myeloma Research and Treatments
- Protein Degradation and Inhibitors
- Genetic and phenotypic traits in livestock
- Dendrimers and Hyperbranched Polymers
- Geothermal Energy Systems and Applications
- MicroRNA in disease regulation
- Soybean genetics and cultivation
- Ubiquitin and proteasome pathways
- Molecular Biology Techniques and Applications
- Signaling Pathways in Disease
- Phase Change Materials Research
- Cancer-related Molecular Pathways
- Monoclonal and Polyclonal Antibodies Research
- Genetic diversity and population structure
- Liver Disease Diagnosis and Treatment
- Cold Atom Physics and Bose-Einstein Condensates
- Orbital Angular Momentum in Optics
- Solar Energy Systems and Technologies
- Genetic Mapping and Diversity in Plants and Animals
- Cancer therapeutics and mechanisms
- Cancer-related molecular mechanisms research
- Quantum Information and Cryptography
- Immunodeficiency and Autoimmune Disorders
Jilin Jianzhu University
2023-2025
Southern Medical University
2022-2024
Lanzhou University
2023-2024
Lanzhou University Second Hospital
2024
Qingdao University
2021-2024
Affiliated Hospital of Qingdao University
2022-2024
Ministry of Agriculture and Rural Affairs
2024
Nanfang Hospital
2022-2024
Beijing Academy of Agricultural and Forestry Sciences
2023-2024
Shandong Provincial Hospital
2022-2023
Abstract Myosin 1b (Myo1b) is an important single-headed membrane-associated motor of class I myosins that participate in many critical physiological and pathological processes. Mounting evidence suggests the dysregulation Myo1b expression has been extensively investigated development progression several tumors. However, functional mechanism CRC angiogenesis autophagy remains unclear. Herein, we found was upregulated tissues its high correlated with worse survival. The overexpression...
The new type of support disc-type anchor is an expanded body with broad application prospects, and its load-bearing performance significantly better than that traditional anchors. However, there a problem premature shear damage in In order to solve this problem, paper improves the disk anchor. It conducts cyclic loading tests on anchors different disc diameters, thicknesses, anchoring section lengths so as simulate repeated loads are subjected actual projects. function model suitable for...
Discovering the genotype-phenotype relationship is crucial for genetic engineering, which will facilitate advances in fields such as crop breeding, conservation biology, and personalized medicine. Current research usually focuses on single species small datasets due to limitations phenotypic data collection, especially traits that require visual assessments or physical measurements. Deciphering complex composite phenotypes, morphology, from at scale remains an open question. To break through...
Abstract Background Although the inherited risk factors associated with fatty liver disease are well understood, little is known about genetic background of metabolic dysfunction-associated steatotic (MASLD) and its related health impacts. Compared to non-alcoholic (NAFLD), MASLD presents significantly distinct diagnostic criteria, epidemiological clinical features, but variants yet be investigated. Therefore, we conducted this study assess interactions between MASLD-related...
Objective This study aimed to investigate the efficacy and safety of belimumab for treating children with refractory childhood-onset systemic lupus erythematosus (cSLE). Methods Twenty-six cSLE patients who received treatment in our hospital from January 2020 September 2021 (23 them more than 52 weeks) were enrolled this study. Their clinical laboratory data, assessment disease activity, glucocorticoid dosage, treatment-emergent adverse events (TEAEs) retrieved analysis. The paired samples...
Objective To explore the clinical characteristics and treatment outcomes of children with central nervous system (CNS) involvement in eosinophilic granulomatosis polyangiitis (EGPA). Methods A child who presented EGPA complicated by CNS was admitted to our hospital June 2023. The features were analyzed retrospectively, relevant literatures reviewed provide a comprehensive overview this condition. Results ten-year-old girl, had history recurrent cough asthma accompanied peripheral blood...
Choosing the appropriate concentration and volume of anesthetics is critical for a successful nerve block. The current study aimed to determine minimum effective (MEV) 0.5% ropivacaine US-guided CEB in 90% patients (MEV90) undergoing anorectal surgery. aims were reduce occurrence complications associated with sacral blockade surgery, broaden indications surgical procedures treatment, improve patient satisfaction. This presents groundwork development individualized anesthetic programs. We...
Kiwifruits are often exposed to various temperature fluctuation (TF) during postharvest storage. To evaluate the effect of TF on qualities kiwifruits, fruits were stored at 2 ºC, ºC or 5 (TF2ºC-5ºC), 7 (TF2ºC-7ºC), alternating every 12 h. Observations revealed that kiwifruits constant °C showed lowest loss weight and vitamin C due minimum ethylene production respiratory rate compared TF2ºC-5ºC TF2ºC-7ºC. Moreover, results RT-qPCR verifed expression genes encoding polygalacturonase,...
Kiwifruits are often exposed to various temperature fluctuations (TFs) during postharvest transportation and storage. To evaluate the effect of TFs on qualities kiwifruits storage, were stored at 2 °C, °C or 5 (TF2 °C–5 alternating every 12 h), 7 °C–7 h) for 3 d before long time storage °C. Observations revealed that a constant showed lowest loss weight vitamin C because minimized ethylene production respiratory rate compared with TF2 Moreover, results RT-qPCR verified expression levels...
Abstract Objective To compare the outcomes of patients undergoing Retroperitoneal laparoscopic Radical nephrectomy (RLRN) and Transperitoneal (TLRN). Methods A total 120 with localized renal cell carcinoma were randomized into either RLRN or TLRN group. Mainly by comparing patient perioperative related data, surgical specimen integrity, pathological results tumor results. Results Each group comprised 60 patients. The two equivalent in terms outcomes. mean integrity score was significantly...
Abstract Background Hepatocellular carcinoma (HCC) is one of the most common and malignant tumors in digestive tract. Tumor Suppressor Candidate 3 (TUSC3) subunit endoplasmic reticulum Oligosaccharyl transferase (OST) complex, which plays an important role N-glycosylation during protein folding process. However, TUSC3 initiation progression HCC has not been mentioned yet. In present study, we aim to investigate effects on HCC. Methods Immunohistochemical assay qRT-PCR were used detect...
As a famous underground heat transfer structure, energy piles have been widely used in geothermal development. However, the effect of cyclic temperature field on ultimate load capacity single pile is substantial. In this study, model were poured using phase change storage concrete based Gum Arabic with polyethylene glycol 600. An indoor modeling test was designed to compare (GPEP) traditional (TEP). The bearing obtained through theoretical formulas and static tests performance superiority...
Abstract Background To investigate the role of circNFIB in alleviation myocardial fibrosis by endogenous sulfur dioxide (SO 2 ). Methods We stimulated cultured neonatal rat cardiac fibroblasts with transforming growth factor-β1 (TGF-β1) and developed an vitro model. Lentivirus vectors containing aspartate aminotransferase 1 (AAT1) cDNA were used to overexpress AAT1, siRNA was silence circNFIB. The SO , collagen, circNFIB, Wnt/β-catenin, p38 MAPK pathways examined each group. Results In...
Background Pulmonary hypertension (PH) is one of the most common complications associated with end-stage renal disease (ESRD). Though numerous risk factors have been founded, other remain unidentified, particularly in patients undergoing maintenance hemodialysis elder age. Soluble Fas (sFas) and its ligand FasL (sFasL) reported chronic patients; however, they not identified PH patients. We aimed to determine roles sFas/sFasL onset ESRD. Methods Altogether, 163 aged 68.00 ± 10.51 years ESRD...