A5024843746- Genomics and Phylogenetic Studies
- Microbial Community Ecology and Physiology
- Plant Disease Resistance and Genetics
- Microbial Natural Products and Biosynthesis
- Actinomycetales infections and treatment
- Bacteriophages and microbial interactions
- Plant Pathogens and Fungal Diseases
- Escherichia coli research studies
- Enzyme Production and Characterization
- Salmonella and Campylobacter epidemiology
- Viral gastroenteritis research and epidemiology
- Entomopathogenic Microorganisms in Pest Control
- Identification and Quantification in Food
- Food Quality and Safety Studies
- Plant-Microbe Interactions and Immunity
- Probiotics and Fermented Foods
- Plant tissue culture and regeneration
- Metal Extraction and Bioleaching
- Microbial Metabolism and Applications
- Bacterial biofilms and quorum sensing
- Indoor Air Quality and Microbial Exposure
- Insect and Pesticide Research
- Biochemical and Structural Characterization
- Studies on Chitinases and Chitosanases
- Legume Nitrogen Fixing Symbiosis
Yonsei University
2021-2024
Korea Research Institute of Bioscience and Biotechnology
2013-2023
RELX Group (Netherlands)
2017-2023
Chonnam National University Hospital
2023
University of Nebraska–Lincoln
2020-2023
Korea Forest Service
2019-2022
National Cancer Center
2016
Korea Occupational Safety and Health Agency
2014
University of Wisconsin–Madison
2011-2014
Buddhist Digital Resource Center
2014
Members of the genus Xenorhabdus are entomopathogenic bacteria that associate with nematodes. The nematode-bacteria pair infects and kills insects, both partners contributing to insect pathogenesis providing nutrition nematode from available insect-derived nutrients. provides protection predators, access nutrients, a mechanism dispersal. bacterial Photorhabdus also nematodes kill genera provide similar services their different hosts through unique physiological metabolic mechanisms. We...
Bacteria and fungi are major phytopathogens which substantially affect global agricultural productivity. In the present study, Streptomyces sp. AN090126, isolated from suppressive soil in Korea, showed broad-spectrum antagonistic activity against various phytopathogenic bacteria fungi. 96-well plate assay, fermentation filtrate of AN090126 exhibited antimicrobial activity, with a minimum inhibitory concentration (MIC) 0.63-10% for 0.63-3.3% The MIC partially purified fraction was 20.82-250...
Xenocoumacin 1 (Xcn1) and xenocoumacin 2 (Xcn2) are the major antimicrobial compounds produced by Xenorhabdus nematophila. To study role of Xcn1 Xcn2 in life cycle X. nematophila 14 gene cluster (xcnA-N) required for their synthesis was identified. Overlap RT-PCR analysis identified six xcn transcripts. Individual inactivation non-ribosomal peptide synthetase genes, xcnA xcnK, polyketide xcnF, xcnH xcnL, eliminated production. levels expression xcnA-L were increased an ompR strain while...
Xenorhabdus nematophila is an emerging model for both mutualism and pathogenicity in different invertebrate hosts. Here we conduct a mutant study of the EnvZ-OmpR two-component system flagella sigma factor, FliA (sigma28). Both ompR envZ strains displayed precocious swarming behaviour, elevated flhD fliA mRNA levels early production lipase, protease, haemolysin antibiotic activity. Inactivation eliminated exoenzyme which was restored by complementation with fliAZ operon. flhA, gene encoding...
A Gram-positive short rod isolated from a saline soil in China was characterized using polyphasic approach. This actinobacterium grew over wide salinity range [0–15 % NaCl, 0–20 KCl and 0–30 MgCl 2 .6H O (w/v); optimum concentrations for growth were 5 5–10 KCl, 10 O]. The temperature pH 28–30 °C 7·0–8·0, respectively. Chemotaxonomic features (peptidoglycan-type B2 β with glycolyl residues; major menaquinones MK-10 MK-11; predominating iso- anteiso-branched cellular fatty acids; DNA G+C...
Staphylococcus aureus is a versatile human pathogen that produces diverse virulence factors, and its biofilm cells are difficult to eradicate due their inherent ability tolerate antibiotics. The anti-biofilm activities of the spent media 252 endophytic microorganisms were investigated using three S. strains. An attempt was made identify compounds in active assess anti-hemolytic hydrophobicities order investigate action mechanisms. Unlike other antibiotics, actinomycin D (0.5 μg ml−1) from...
A moderately halophilic actinomycete strain, designated YIM 90010 T , was isolated from a soil sample collected hypersaline habitat in Xinjiang Province, China, and then investigated using polyphasic taxonomic approach. The strain produced abundant aerial mycelia fragmented substrate on most media tested; the optimum NaCl concentration for growth 10 % (w/v) temperature pH were 28 °C 7·2, respectively. Chemotaxonomically phylogenetically, related to members of genus Nocardiopsis . isolate...
A moderately halophilic bacterium, strain SS20 T , capable of growing at salinities 1–20 % (w/v) NaCl was isolated from a solar saltern the Dangjin area in Korea and characterized taxonomically. Strain Gram-negative bacterium comprising motile, short rods. Its major cellular fatty acids were C 18 : 1 ω 7 c 19 0 8 cyclo 16 . The DNA G+C content 70 mol% predominant ubiquinone Q-9. Phylogenetic analysis based on 16S rRNA gene sequences showed that belonged to genus Halomonas levels sequence...
A mesophilic strain, designated 9500T, was isolated from a soil sample collected Sobaek Mountain, South Korea, and its taxonomic position investigated by using polyphasic approach. The novel strain grew well on different ISP media no diffusible pigments were produced. optimum temperature for growth 32 degrees C. aerial mycelium developed, but not fragmented. Gram-positive, non-motile formed endospores vegetative hyphae with spiny surface. Cell walls of 9500T contained meso-diaminopimelic...
A Gram-stain-positive actinobacterium, designated strain YIM 93316 T , was isolated from a salt lake in Xinjiang Province, north-west China, and subjected to polyphasic taxonomic study. The isolate grew at 10–45 °C, pH 6–9 the presence of 1–15 % (w/v) NaCl, but no growth observed absence NaCl. cell-wall diamino acid contained alanine, glutamine lysine with peptidoglycan type A4 α . Polar lipids diphosphatidylglycerol, phosphatidylglycerol, phosphatidylinositol, phosphatidylinositol...
Abstract Endophytic bacteria, a rich source of bioactive secondary metabolites, are ideal candidates for environmentally benign agents. In this study, an endophytic strain, Streptomyces sp. AE170020, was isolated and selected the purification nematicidal substances based on its high activity. Two highly active components, aureothin alloaureothin, were identified, their chemical structures determined using spectroscopic analysis. Both compounds suppressed growth, reproduction, behavior...
A mesophilic bacterium, designated strain YIM 31327 T , was isolated from a forest soil sample collected Yunnan Province, China, and then investigated using polyphasic approach. The grew optimally at 28–30 °C pH 7·2. cells were Gram-negative, short, rod-shaped, motile non-spore-forming with flagella. major ubiquinone Q-8 the cellular fatty acids C 16 : 0 12 . DNA G+C content of 62·8 mol%. Phylogenetic analysis revealed that member β - Proteobacteria being most closely related to Duganella...
An actinobacterium, strain YIM 70010 T , which was isolated from a desert soil sample collected in Egypt, subjected to polyphasic taxonomy study. The organism alkalitolerant and its optimum growth occurred at pH 8·0–9·0. isolate contained chemotaxonomic markers that were characteristic of the genus Citricoccus i.e. peptidoglycan type Lys–Gly–Glu (variation A4 α ), predominant menaquinone MK-9(H 2 ) polar lipid profile consisting diphosphatidylglycerol, phosphatidylglycerol,...
A moderately halophilic, Gram-negative bacterium, strain BH539 T , which was isolated from a solar saltern at Taean in Korea, considered to be member of the genus Halomonas . Strain grew salinities 1–25 % (w/v) and temperatures 10–45 °C. Cells were short rods that motile by means several flagella. Their major fatty acids C 18 : 1 ω 7 c 16 0 19 cyclo 8 The genomic DNA G+C content about 65 mol% predominant ubiquinone Q-9. Phylogenetic analyses based on 16S rRNA gene sequences indicated isolate...
A novel Gram-staining-negative, short rod, non-motile, non-spore-forming, aerobic bacterium, designated strain YIM M12096T, was isolated from deep-sea sediment collected the Indian Ocean. Optimal growth conditions of were observed at 25-30 °C, pH 6.0 and in presence 3-5 % (w/v) NaCl. Phylogenetic analysis based on 16S rRNA gene sequences indicated that M12096T closely related to Nitratireductor indicus C115T (97.4 sequence similarity) Mesorhizobium thiogangeticum SJTT (97.3 %). The strain,...
Here, we fabricated polypyrrole nanoparticles (PPys) (termed HA10-PPy, HA20-PPy, and HA40-PPy) doped with different average molecular weight hyaluronic acids (HAs) (10, 20, 40 kDa, respectively), evaluated the effect of HA on photothermal induction, fluorescence quenching, drug loading efficiencies. Doxorubicin-loaded HA-doped PPys (DOX@HA-PPys) could be used for imaging therapy triple-negative breast cancer (TNBC). Fluorescence turn-on, stimuli-responsive release, photo-induced heating...
A Gram-stain-negative, rod-shaped, non-motile and aerobic bacterial strain, designated CHL1T, was isolated from a sludge sample collected sewage treatment tank of an agricultural chemical factory. The strain grew at salinities 0.5–5 % (w/v) NaCl (optimum 2.5 %). Growth occurred pH 6.0–8.0 7.0) 5–40 °C 28–30 °C). genomic DNA G+C content determined to be 70.4 mol%. Q-10 detected as the respiratory quinone. major fatty acids (>10 %) were C18 : 1ω7c and/or 1ω6c C16 0. polar lipids consisted...
A polyphasic taxonomic study was carried out on an actinobacterial strain (AN110305T) isolated from soil sampled in the Republic of Korea. Cells were Gram-stain-positive, aerobic, non-motile and rod-shaped. Comparative 16S rRNA gene sequence studies showed a clear affiliation AN110305T with Actinomycetia, highest pairwise similarities to Goodfellowiella coeruleoviolacea DSM 43935T (97.6%), Umezawaea tangerina MK27-91F2T (97.0%), Kutzneria chonburiensis NBRC 110610T (96.9%), buriramensis A-T...