A5072348237- Advanced Radiotherapy Techniques
- Cancer, Lipids, and Metabolism
- Biomedical and Engineering Education
- Advances in Oncology and Radiotherapy
- Epigenetics and DNA Methylation
- Cancer-related molecular mechanisms research
- Histone Deacetylase Inhibitors Research
- PI3K/AKT/mTOR signaling in cancer
- Neuroblastoma Research and Treatments
- Cancer, Hypoxia, and Metabolism
- Management of metastatic bone disease
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Spinal Dysraphism and Malformations
- Coenzyme Q10 studies and effects
- Urologic and reproductive health conditions
- Glutathione Transferases and Polymorphisms
- Radiation Dose and Imaging
- Tea Polyphenols and Effects
- Glioma Diagnosis and Treatment
- Tannin, Tannase and Anticancer Activities
- Molecular Communication and Nanonetworks
- Effects of Radiation Exposure
- RNA modifications and cancer
- Ferroptosis and cancer prognosis
University of Iowa Hospitals and Clinics
2024
University of Iowa
2023
University of Wisconsin–Madison
2012-2018
An effective didactic curriculum is a cornerstone for successful residency program, as it the basis upon which residents acquire necessary knowledge and perspective to provide high-quality, evidence-based care. Here we describe our success in creating standardized clinical radiation oncology - one that was well-received led significantly improved performance on national in-service examination.
Abstract Hyperactivated AKT kinase due to loss of its negative regulator PTEN influences many aspects cancer biology, including chromatin. primarily regulates acetyl-CoA production and phosphorylates histone-modulating enzymes, resulting in their activation or inhibition. Therefore, understanding the therapeutic impact inhibition on chromatin-related events is essential. Here, we report that prostate-specific knockout mice significantly induces di- trimethylation H3K4 with concomitant...
Pediatric low-grade tectal gliomas are rare, indolent tumors of the brain stem. We reviewed outcomes pediatric patients who received a diagnosis and report dosimetric parameters for those receiving radiation therapy (RT).
Background Peritoneal carcinomatosis is a particularly rare presentation of prostate cancer. Here we report clinical case surgically identified peritoneal at the time planned robotic prostatectomy in patient with history prostatic urethral lift procedure. Case A 72-year-old man, urinary retention managed tamsulosin, presented to his local urologist. Prostatic procedures were performed for symptom management. After definitive uptrend prostate-specific antigen (PSA) values, biopsy was...
Abstract In preclinical animal models (-)-epigallocatechin-3-gallate (EGCG), the major polyphenol of green tea, has shown excellent effects in preventing and/or treating many cancers including prostate cancer (PCa). Chemoprevention is a practical approach for management however its applicability to humans met with limited success due several issues bioavailability. We recently employed use nanotechnology improve outcome natural agents chemoprevention and termed concept as...
<p>Supplementary Figure S1: showing H&E staining of PTEN wild type (A) and knock out mice treated with vehicle (B) perifosine (C).</p>
<div>Abstract<p>Hyperactivated AKT kinase due to loss of its negative regulator PTEN influences many aspects cancer biology, including chromatin. primarily regulates acetyl-CoA production and phosphorylates histone-modulating enzymes, resulting in their activation or inhibition. Therefore, understanding the therapeutic impact inhibition on chromatin-related events is essential. Here, we report that prostate-specific knockout mice significantly induces di- trimethylation H3K4 with...
<div>Abstract<p>Hyperactivated AKT kinase due to loss of its negative regulator PTEN influences many aspects cancer biology, including chromatin. primarily regulates acetyl-CoA production and phosphorylates histone-modulating enzymes, resulting in their activation or inhibition. Therefore, understanding the therapeutic impact inhibition on chromatin-related events is essential. Here, we report that prostate-specific knockout mice significantly induces di- trimethylation H3K4 with...
<p>Supplementary Figure S1: showing H&E staining of PTEN wild type (A) and knock out mice treated with vehicle (B) perifosine (C).</p>
Abstract One of the common contributors to pre-disposition most human cancers is inappropriate activation AKT due loss its negative regulator PTEN. Activated regulates changes in metabolic processes such as acetyl-CoA production that impacts chromatin. phosphorylates a wide variety histone modulating enzymes including acetyltransferases and methyltransferases resulting their hyperactivation or inhibition. Therefore, understanding impact inhibition on global modification would be ideal...