A5101534309- Genetic Associations and Epidemiology
- Metabolomics and Mass Spectrometry Studies
- Bioinformatics and Genomic Networks
- NF-κB Signaling Pathways
- Catalytic Alkyne Reactions
- Biological Activity of Diterpenoids and Biflavonoids
- Bioactive Natural Diterpenoids Research
- Prostate Cancer Diagnosis and Treatment
- Advanced Fiber Laser Technologies
- Immune Response and Inflammation
- Oxidative Organic Chemistry Reactions
- Genetics and Neurodevelopmental Disorders
- Synthesis of Organic Compounds
- Advanced Photonic Communication Systems
- Bioactive Compounds and Antitumor Agents
- Congenital heart defects research
- Bioactive natural compounds
- Pluripotent Stem Cells Research
- Photonic and Optical Devices
- Wound Healing and Treatments
Monash University
2024
Institute of Semiconductors
2024
University of Chinese Academy of Sciences
2024
Seventh People's Hospital of Shanghai
2023
Shanghai University of Traditional Chinese Medicine
2023
Shanxi University
2023
Guangxi Medical University
2019-2022
Zhejiang Chinese Medical University
2020
A synthetic method for the efficient preparation of partially hydrogenated benzo[f]cyclobuta[cd]cyclopenta[h]benzofurans and cyclopropa[c]chromen-3a(1H)-ols that relies on gold(I)-catalyzed cascade cycloisomerization 3-allyloxy-1,6-diynes is described.
Abstract A new strategy for thiochromen‐4‐one synthesis that relies on the denitrative formal [5+1] cycloaddition of 1‐(2‐nitrophenyl)‐2‐yn‐1‐ones with thioacetamide is described. Achieved under reaction conditions did not require transition metal catalysis, nor exclusion air or moisture, suggested to involve exploiting propensity undergo hydrolysis basic conditions. This follows by addition ensuing sulfide anion 1,3‐alkynone and a nucleophilic aromatic substitution rearomatization cascade...
Objective. Prostatitis is a common disease of the male genitourinary system, which seriously disturbs physical and mental health patients. It related to many factors such as living habits, age, race, but etiology has not been fully elucidated. This study investigated whether there causal relationship between clinical biochemical indicators (i.e., intermediate phenotype) prostatitis through Mendelian randomization. The subjects were patients SNPs in Guangxi Fangchenggang examination cohort....
This paper presents a high-directionality optical grating antenna for chip-level LiDAR applications. The antenna, designed on silicon-nitride-nitride platform, consists of two vertically stacked layers with nitride waveguide layer in between. By optimizing the periods, duty cycles, and relative offset between using particle swarm optimization algorithm, directionality 87.8% (0.56 dB) at 1550 nm wavelength minimum coupling loss 1.7 dB were achieved. performance was demonstrated chip-to-chip...
One new lathyrane-type diterpenoid, euphlathin A (1), and 11 known analogues (2–12), were isolated from the fruits of Euphorbia lathyris. Their structures elucidated by spectroscopic data. The absolute configurations 1 established single-crystal X-ray crystallography. All diterpenoids (1–12) evaluated for antiproliferative activity against human hypertrophic scar (HTS) cells. Compound exhibited significantly HTS cells growth with an IC50 value 6.33 μM. Morphological features apoptosis in...
The disconnected-interacting protein 2 homolog A (DIP2A), a member of family, has been shown to be involved in human nervous system-related mental illness. This is highly expressed the system mouse. Mutation mouse DIP2A causes defects spine morphology and synaptic transmission, autism-like behaviors, defective social novelty [5], [27], indicating that critical maintenance neural development. However, role differentiation yet investigated.
Abstract Background: Phenomics provides a new technologies and platforms as systematic phenome-genome approach. However, few studies have reported on the system mining of shared genetics among clinical biochemical indices based methods, especially in China. This study aimed to apply phenomics systematically explore 29 Fangchenggang Area Male Health Examination Survey cohort. Result: A total 1,999 subjects with 709,211 single nucleotide polymorphisms were subjected analysis. Three...
Abstract Background: Phenomics provides a new technologies and platforms as systematic phenome-genome approach. However, few studies have reported on the system mining of shared genetics among clinical biochemical indices based methods, especially in China. This study aimed to apply phenomics systematically explore 29 Fangchenggang Area Male Health Examination Survey cohort. Result: A total 1,999 subjects with 709,211 single nucleotide polymorphisms were subjected analysis. Three...
Abstract Background: Phenomics provides a new technologies and platforms as systematic phenome-genome approach. However, few studies have reported on the system mining of shared genetics among clinical biochemical indices based phenomics methods, especially in China. This study aimed to apply systematically explore 29 Fangchenggang Area Male Health Examination Survey cohort. Result: A total 1,999 subjects with 709,211 single nucleotide polymorphism were subjected analysis. Three...
Abstract Background: Phenomics provides a new technologies and platforms as systematic phenome-genome approach. However, few studies have reported on the system mining of shared genetics among clinical biochemical indices based methods, especially in China. This study aimed to apply phenomics systematically explore 29 Fangchenggang Area Male Health Examination Survey cohort. Result: A total 1,999 subjects with 709,211 single nucleotide polymorphisms were subjected analysis. Three...
Abstract Background: Phenomics provides new technologies and platforms as a systematic phenome-genome approach. However, few studies have reported on the mining of shared genetics among clinical biochemical indices based phenomics methods, especially in China. This study aimed to apply systematically explore 29 Fangchenggang Area Male Health Examination Survey cohort. Result: A total 1,999 subjects with 709,211 single nucleotide polymorphisms (SNPs) were subjected analysis. Three...