A5009533826- CAR-T cell therapy research
- Plant Molecular Biology Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Renal cell carcinoma treatment
- Botulinum Toxin and Related Neurological Disorders
- Multiple and Secondary Primary Cancers
- Plant Stress Responses and Tolerance
- Pain Mechanisms and Treatments
- Digital Media and Visual Art
- Acupuncture Treatment Research Studies
- Cancer Mechanisms and Therapy
- Creativity in Education and Neuroscience
- COVID-19 and healthcare impacts
- COVID-19 Clinical Research Studies
- Occupational and environmental lung diseases
- Plant Reproductive Biology
- Persona Design and Applications
- Pain Management and Treatment
- Endoplasmic Reticulum Stress and Disease
- Cellular transport and secretion
- Economic and Financial Impacts of Cancer
- Monoclonal and Polyclonal Antibodies Research
- Liver Disease and Transplantation
- Art Education and Development
- Lipid Membrane Structure and Behavior
Hangzhou Normal University
2024-2025
University of Science and Technology of China
2024-2025
University of Delaware
2022-2024
Purdue University West Lafayette
2022
Nanjing Normal University
2022
Huashan Hospital
2014-2020
Fudan University
2014-2020
Liver venous deprivation (LVD; simultaneous portal vein embolization and hepatic embolization) has been the latest surgical strategy for rapid future liver remnant (FLR) hypertrophy. The aim of this study was to assess feasibility, safety, efficacy LVD following arterial chemoembolization (TACE-LVD) before major hepatectomy hepatocellular carcinoma (HCC). A retrospective analysis outcomes 23 HCC patients who underwent TACE-LVD at our center between October 2019 2023 conducted. An assessment...
Intracerebral hemorrhage (ICH) is a significant global public health issue that characterized by rapid start, severe symptoms, and poor prognosis. It the most common type of hemorrhagic stroke. We analyzed intracranial incidence, mortality, disability-adjusted life years (DALYs), corresponding age-standardized rates (ASRs) estimated annual percentage changes (EAPCs) using GBD 2021 data. The data were further stratified age, sex, region to assess burden ICH from 1990 2021, providing...
Kidney cancer, a prevalent malignant tumor in the urinary system, poses significant disease burden and remains crucial public health concern. Utilizing GBD(Global Burden of Disease)2021 data, our study examined standardized incidence, mortality, prevalence, DALYs(Disability Adjusted Life Years) rate renal cancer. We calculated [1-MIR(Mortality to Incidence Ratio)] value assess treatment outcomes survival rates, employed joinpoint regression model determine AAPC(Average Annual Percentage...
Pneumoconiosis, a group of occupational lung diseases caused by prolonged inhalation mineral dust, remains critical global health threat due to persistent workplace exposures in high-risk industries such as mining, construction, and artificial stone processing. These hazards are exacerbated inadequate dust control measures, insufficient use personal protective equipment (PPE), underreporting low-and middle-income countries (LMICs). Emerging industries, including engineered fabrication, have...
Electroacupuncture has traditionally been used to treat pain, but its effect on pain following brachial plexus injury is still unknown. In this study, rat models of an avulsion the left root (associated with upper-limb chronic neuropathic pain) were given electroacupuncture stimulation at bilateral Quchi (LI11), Hegu (LI04), Zusanli (ST36) and Yanglingquan (GB34). After therapy, in rats' upper limbs was significantly attenuated. Immunofluorescence staining showed that expression β-endorphins...
Background: Adjuvant therapy is used to reduce the risk of hepatocellular carcinoma (HCC) recurrence and improve patient prognosis. Exploration treatment strategies that are both efficacious safe has been extensively performed in recent years. Although donafenib demonstrated good efficacy advanced HCC, its use as adjuvant HCC not reported. Objectives: To investigate safety postoperative patients with at high-risk recurrence. Design: Retrospective study. Methods: A total 196 were included...
Developmental and environmental cues induce Ca2+ fluctuations in plant cells. Stimulus-specific spatial-temporal patterns are sensed by cellular binding proteins that initiate signaling cascades. However, we still know little about how stimulus specific signals generated. The specificity of a signal may be attributed to the sophisticated regulation activities channels and/or transporters response given stimulus. To identify these components understand their functions, it is crucial use...
Background: This study was to explore the potential mechanism of naprapathy in treating neuropathic pain (NP) after brachial plexus injury (BPI). Methods: Totally 72 rats were randomly divided into normal group, model control and group (n=24 per group). A right upper-limb chronic NP established, administered at C5-T1 Jiaji Points on 4th day modeling. Naprapathy performed for 15 min once daily with a frequency 60 minute. The treatment applied altogether 28 days. Cold threshold mechanical...
<title>Abstract</title> <bold>OBJECTIVE:</bold> To explore trends in pneumoconiosis incidence, prevalence, mortality and DALYs 2021 China, Japan, Korea, East Asia a cross-sectional study from 1990 to <bold>RESEARCH DESIGN:</bold> Data the Global Burden of Disease (GBD) for relevant countries regions were used this study. People with region aged 15-70 years included analysis analysed 18 May 2024 10 June 2024. Main outcome indicators: mortality, DALYs. interannual stratified according country,...
<title>Abstract</title> Background Kidney cancer, a prevalent malignant tumor in the urinary system, poses significant disease burden and remains crucial public health concern. Methods Utilizing GBD2021 data, our study examined standardized incidence, mortality, prevalence, DALYs rate of renal cancer. We calculated (1-MIR) value to assess treatment outcomes survival rates, employed joinpoint regression model determine AAPC, conducted comparative longitudinal analyses between China global...
<title>Abstract</title> Objective To understand the construction of mobile App medical service platforms in general hospitals China. Methods 50 were randomly selected from seven regions The user interface score and number functions statistically described statistical tables, analyzing differences scores by region using analysis variance. Results average evaluation all was above 70 points, between 12–14 items, 8–11 items 5–7 accounted for 38%, 52% 10% overall hospitals, respectively, ANOVA...
The purpose is to explore new cultivation modes of college students' national cognition and cultural acceptance. Deep learning (DL) technology Educational Psychology theory are introduced, the influence art journal reading on acceptance analyzed under Psychology. Firstly, background Psychology, acceptance, system discussed following a literature review. DL introduced construct guidance system. can provide users with journals record user habits like duration preferences. Secondly, hypotheses...
Abstract Mitochondrial Ca 2+ ( mt ) homeostasis is essential to mitochondrial functions. However, how achieved and the consequences of impaired in plants poorly understood. Here, we demonstrate a critical role for uniporter (MCU) control uptake planta by characterizing MCU mutants overexpressed plants. Impaired MCU-controlled (iMUCH) gain-of-function loss-of-function causes misregulation gene expression that triggers mitonuclear protein imbalance. Transcriptome integrated with proteomics...
Developmental and environmental cues induce Ca2+ fluctuations in plant cells. Stimulus-specific spatial-temporal patterns are sensed by cellular binding proteins that initiate signaling cascades. However, we still know little about how stimulus specific signals generated. The specificity of a signal may be attributed to the sophisticated regulation activities channels and/or transporters response given stimulus. To identify these components understand their functions, it is crucial use...
<h3>Background</h3> IgE-producing multiple myeloma, non-Hodgkin's lymphoma and chronic B cell leukemia are caused by neoplasm of cells. Several chimeric antigen receptor (CAR) T-cell therapies have been approved for treating malignancies, but they target linage markers CD19 or BCMA indiscriminately eliminate both malignant cells normal This leads to general plasma aplasia compromised humoral immune responses. <h3>Methods</h3> To specifically cancer cells, we developed a CAR that recognizes...
<h3>Background</h3> Neoplasm of IgE-producing B lineage cells gives rise to IgE myeloma, chronic cell leukemia and Hodgkin's lymphoma. Although several chimeric antigen receptor (CAR) T-cell therapies have been approved for treating malignancies by targeting the marker CD19 or maturation (BCMA), these approaches indiscriminately eliminate both cancerous most normal cells. This leads general plasma aplasia compromised humoral immune responses. <h3>Methods</h3> To specifically target cancer...
Abstract A major challenge in T cell therapy against solid tumors is the heterogeneity of tumor antigen (TA) expression. Elimination TA+ cells often fails to suppress growth due expansion TA− cells. To address this, we developed tumor-activated alloreactive (TAATs) that display alloreactivities only tumors. TAATs lack endogenous CD3ɛ expression and contain a sensing mechanism drives an exogenous copy presence are therefore inactive normal tissues retention TCR/CD3 ER but become attack all...