A5092394437- Liver Disease Diagnosis and Treatment
- Liver physiology and pathology
- Organ Transplantation Techniques and Outcomes
- Hepatocellular Carcinoma Treatment and Prognosis
German Cancer Research Center
2023-2024
Heidelberg University
2023-2024
Chronic liver diseases are worldwide on the rise. Due to rapidly increasing incidence, in particular Western countries, metabolic dysfunction-associated steatotic disease (MASLD) is gaining importance as can develop into hepatocellular carcinoma. Lipid accumulation hepatocytes has been identified characteristic structural change MASLD development, but molecular mechanisms responsible for progression remained unresolved. Here, we uncover primary from a preclinical model fed with diet (WD) an...
Abstract Chronic liver diseases are worldwide on the rise. Due to rapidly increasing incidence, in particular Western countries, Non-alcoholic fatty disease (NAFLD) is gaining importance as can develop into hepatocellular carcinoma. Lipid accumulation hepatocytes has been identified characteristic structural change NAFLD development, but molecular mechanisms responsible for progression remained unresolved. Here, we uncover primary from a preclinical model fed with diet (WD) strong...