A5041794292- Traumatic Brain Injury and Neurovascular Disturbances
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Neurosurgical Procedures and Complications
- Intracerebral and Subarachnoid Hemorrhage Research
- Cardiac Arrest and Resuscitation
- Optical Imaging and Spectroscopy Techniques
- Vascular Malformations Diagnosis and Treatment
- Palliative Care and End-of-Life Issues
- Simulation-Based Education in Healthcare
- Traumatic Brain Injury Research
- Organ Transplantation Techniques and Outcomes
- Bacterial Infections and Vaccines
- Apelin-related biomedical research
- Gynecological conditions and treatments
- Multiple Sclerosis Research Studies
- Liver Disease and Transplantation
- Patient Safety and Medication Errors
- Cerebrospinal fluid and hydrocephalus
- Meningioma and schwannoma management
- Infectious Encephalopathies and Encephalitis
- Biliary and Gastrointestinal Fistulas
- Chronic Kidney Disease and Diabetes
- Public Health and Social Inequalities
Finis Terrae University
2023-2024
Clínica Las Condes
2017-2024
Clínica Alemana
2015-2019
Universidad del Desarrollo
2012-2019
Universidad del Desarrollo del Estado de Puebla
2013-2014
Columbia University Irving Medical Center
2012
Columbia University
2012
University of Chile
2006-2008
Hospital Clínico de la Universidad Católica
2008
Hospital Clínico de la Universidad de Chile
2008
Dynamic cerebral autoregulation (DCA) is the continuous counterregulation of blood flow to fluctuations in pressure. DCA can become impaired after acute stroke, but it remains unclear what extent and over interval this occurs.We included 28 patients (NIHSS = 12 ± 6.5, age 68.4 17.1, 16F) with large-vessel ischemic stroke middle artery territory 29 healthy controls (mean 54.9 9, 16F). was assessed by simultaneous measurement pressure together velocities using finger plethysmography/arterial...
Cerebral autoregulation (CA) enables the brain to maintain stable cerebral blood flow (CBF). CA can be assessed noninvasively by determining correlations between CBF velocity (CBFV) and spontaneous changes in pressure. Postrecording signal analysis methods have included both frequency- time-domain methods. However, test-retest reliability, cross-validation, determination of normal values not been adequately established.In 53 healthy volunteers, a transfer function was applied calculate phase...
To determine the intra- and interrater agreement of mean flow velocity (MFV) pulsatility index (PI) measurement in middle cerebral arteries, assessed by transcranial Doppler (TCD) with M-mode. Masked experienced neurosonologists performed TCD M-mode using handheld probe healthy adult volunteers. The Bland–Altman method for concordance intraclass correlation coefficient were used. Seventy-seven volunteers seven raters participated (3 on regular shift 4 off-shift). intrarater absolute...
La simulación clínica es una estrategia eficaz para mejorar la seguridad del paciente. in situ puede tener beneficios al utilizar las instalaciones de cuidados intensivos, el equipo, los suministros clínicos habituales y ser realizado durante jornada laboral. El objetivo este estudio fue evaluar percepción participantes un programa alta fidelidad en Centro Paciente Crítico Adulto. Posterior a debriefing simulaciones realizadas Unidad Adulto Clínica Las Condes, se aplicó encuesta anónima...
Critically ill patients undergoing extracorporeal membrane oxygenation (ECMO) exhibit unique pharmacokinetics. This study aimed to assess the achievement of vancomycin therapeutic targets in these patients.
Stroke is the second specific cause of death in Chile, with a mortality rate 48.6 per 100.000 inhabitants. It accounts for 6% all hospitalizations among adults.To study type patients hospitalized at Unit general hospital and costs benefits such unit.A descriptive retrospective using patient registry, developed Access that included separate sections ischemic hemorrhagic stroke. Established diagnostic criteria were used. The mean complications also calculated.During 2003, 425 stroke admitted...
Background: Osmotic demyelination syndrome (ODS) with cerebral cortical involvement is a rare complication of severe hyponatremia correction. Careful management crucial, particularly in patients risk factors, such as alcohol use disorder and diabetes insipidus. Case: A patient his 40s history central insipidus developed ODS after 24 mEq/L osmolar increase during the treatment hyponatremia. The patient’s condition progressed into locked-in then improved to spastic tetraparesis basal ganglia...
Thrombolysis for stroke in 93 years old female. Report of one caseMost studies evaluating the usefulness intravenous thrombolysis acute have excluded subjects aged over 80 years.Therefore there is no evidence to support or contraindicate this therapy age group.We report a year-old female subjected using tissue plasminogen activator (r-tPA), according National Institute Neurological Disorders protocol.The treatment was successful, were hemorrhagic complications and three months later, patient...
La falla hepática fulminante (FHF) es una patología poco frecuente con alta mortalidad. Requiere un rápido diagnóstico, manejo etiológico, cuando posible, y terapia de soporte adecuada en la Unidad Cuidados Intensivos espera recuperación o bien esto no ocurre, del tratamiento definitivo rescate que el trasplante hepático. Es necesario protocolización manejo, para realizar práctica sistemática, reproducible evaluable atención clínica requieren estos pacientes por equipo multidisciplinario fin...
El trasplante de órganos es un procedimiento vital para el reemplazo en falla irreversible. En Chile, promedio donantes muy inferior a países que proceso donación está consolidado. Al considerar la escasez disponibles parece fundamental entregar las herramientas permitan pesquisa precoz y manejo adecuado oportuno del potencial donante (PD). PD aquel paciente con una puntuación escala Glasgow (GCS) igual o menor 7, daño neurológico severo identificado como fuera alcance neuro-quirúrgico, se...
Background: Early identification of vasospasm prior to symptom onset would allow prevention delayed cerebral ischemia (DCI) in aneurysmal subarachnoid hemorrhage (aSAH). Dynamic autoregulation (DCA) is a noninvasive means assessing blood flow regulation by determining independence low-frequency temporal oscillations systemic pressure (BP) and velocities (CBFV).
Diagnosis of acute disseminated encephalomyelitis using a stereotaxic biopsy. Report one caseWe report 15 year-old female presenting with behavioral disturbances, headache, left hemiparesis and paresis the vertical gaze.CAT scan magnetic resonance showed an involvement right thalamus, third ventricle medial temporal lobe suggesting encephalitis or lymphoma. 201 Thalium SPECT suggested lymphoma.A biopsy subacute demyelinizing lesion, compatible encephalomyelitis.The patient was treated...