A5018413838- Health and Lifestyle Studies
- Acute Ischemic Stroke Management
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Stroke Rehabilitation and Recovery
- Venous Thromboembolism Diagnosis and Management
- Cerebrovascular and Carotid Artery Diseases
- Global Maternal and Child Health
- Maternal and Perinatal Health Interventions
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac, Anesthesia and Surgical Outcomes
- Maternal and Neonatal Healthcare
- Renal Transplantation Outcomes and Treatments
- Temporomandibular Joint Disorders
- Nutritional Studies and Diet
- Dialysis and Renal Disease Management
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pregnancy and Medication Impact
- Acute Myocardial Infarction Research
- Body Contouring and Surgery
- Ovarian function and disorders
- Birth, Development, and Health
- Cleft Lip and Palate Research
- Growth Hormone and Insulin-like Growth Factors
- Orthodontics and Dentofacial Orthopedics
Clínica Alemana
2015-2025
Universidad del Desarrollo
2015-2025
University of Chile
2015-2024
Finis Terrae University
2018-2024
Instituto de Salud Pública de Chile
2004-2024
Boehringer Ingelheim (India)
2021
PTV Group (Germany)
2021
Weatherford College
2021
Hospital San Borja Arriarán
2019-2021
Universidad de Los Andes, Chile
2011-2020
Outcomes: To compare the benefits of noninvasive ventilation (NIV) plus standard therapy vs. alone in children with acute respiratory failure; assess method effectiveness improving gas exchange and vital signs; safety. Design: Prospective, randomized, controlled study. Site: Two pediatric intensive care units Santiago, Chile, at Clínica Santa María Dávila, respectively. Patients Methods: Fifty patients failure admitted to were recruited; 25 randomly allocated inspiratory positive airway...
Abstract We explored the risk factors for gallbladder cancer and explanations its sharp constant incidence increase in Chile since 1970s. compared 114 consecutive patients with verified cancer, diagnosed 1992–1995, to matched hospital gallstones, using conditional logistic regression analysis. Low education showed a nonsignificant positive relationship [odds ratio (OR) = 2.3, 95% confidence interval (CI) 0.8–6.2], low socioeconomic level significant (OR 5.0, CI 1.5–17.3). A very long history...
Hemodialysis patients (HD) display high rates of cardiac diseases and mortality. In chronic kidney disease, vascular injury leads to coronary artery heart failure, stroke. Carotid intima-media thickness (CIMT) measurements are currently widely used in randomized controlled trials (RCTs) study the efficacy interventions. An RCT was designed for assessment safety effectiveness spironolactone inhibit progression CIMT HD as a primary outcome. Secondary outcomes included plasma potassium.HD were...
Background: There is a paucity of validated instruments for screening depression in adolescent populations Chile.
Abstract Background The safety and oncological efficacy of laparoscopic re-resection incidental gallbladder cancer have not been studied. This study aimed to compare with open incidentally discovered while minimizing selection bias. Methods was a multicentre retrospective observational cohort patients who underwent curative intent at four centres between 2000 2017. Overall survival (OS) recurrence-free (RFS) were analysed by intention treat. Inverse probability surgery treatment weighting...
Clinically depressed individuals respond to different types of antidepressants, suggesting that neurobiological mechanisms may be responsible for their depression. However, animal models characterize this are not yet available. We induced depressive-like behaviors in rats using 2 chronic stress models: restraint small cages or immobilization adaptable plastic cones. Both increased anxiety responses evaluated by novelty-suppressed feeding and the elevated plus-maze; learned helplessness tail...
Satisfaction with care during labor and birth has been associated various obstetric variables. The purpose of this study was to determine which procedures are significant predictors maternal patient satisfaction in a large cross-sectional sample.An observational, 1660 women giving Chilean public hospital facilities conducted from 2012 2013. Data were collected 9 different hospitals 8 regions Chile using 2 instruments, including the American College Nurse-Midwives Intrapartum Care Set locally...
Quadriceps muscle dysfunction is an important contributor to exercise limitation in chronic obstructive pulmonary disease, but little known about skeletal function and its impact on capacity patients with fibrotic idiopathic interstitial pneumonia (IIP). The aim of the study was compare quadriceps strength endurance IIP healthy controls, relate it capacity.Quadriceps endurance, as well respiratory strength, 6-min walk distance were compared among 25 IIP, forced vital mean (standard...
Tubular damage has a role in Diabetic Kidney Disease (DKD). We evaluated the early tubulointerstitial biomarkers type-1 Diabetes Mellitus (T1DM) pediatric participants and studied correlation with classical DKD parameters.Thirty-four T1DM fifteen healthy were enrolled. Clinical biochemical parameters [Glomerular filtration Rate (GFR), microalbuminuria (MAU), albumin/creatinine ratio (ACR), glycated hemoglobin A1c (HbA1c)] evaluated. Neutrophil gelatinase-associated lipocalin (NGAL),...
Introducción Resultados de un estudio previo esta red reportaron modelo atención partería altamente medicalizado. En Chile, resultados señalaron que cerca del 25% las participantes se encontraban insatisfechas con la recibida, incluso informaron maltrato, percepción empoderamiento profesional referido por matronas fue heterogénea, prevaleciendo una pérdida autonomía profesional. Objetivos Identificar madres respecto su satisfacción y respeto sus derechos sexuales reproductivos; según...
Tenecteplase (TNK) has demonstrated to be non-inferior alteplase (ALT) for intravenous thrombolysis (IVT) in acute ischemic stroke (AIS). There are potential workflow benefits associated with TNK use, aiming reduce patient length of stay the emergency department. Our aim was investigate whether routine use during COVID-19 pandemic influenced times compared historical ALT, while maintaining clinical outcomes a non-drip and ship scenario comprehensive center. We included patients AIS admitted...
The impact of a healthy diet on the secondary prevention ischemic stroke (IS) remains uncertain. Levels low-density lipoprotein cholesterol (LDL-C) are inversely associated with risk IS recurrence. A Mediterranean (MeDi), consisting preference for fish/poultry, monosaturated fats from olive oil, fruit, vegetables, whole grains, legumes/nuts and limited red meats, animal sweetened beverages, reduces metabolic syndrome, LDL-C levels risk. Avocados also reduce syndrome but not part traditional...
Background and aims The transformation of modified Rankin Scale (mRS) scores based on the corresponding utilities health-related quality life questionnaires can facilitate capture Patient-Centered Outcomes (PCO) in stroke. We aimed to derive utility-weighted (UW-mRS) values by mapping mRS functional status EQ-5D-3L a population-based cohort stroke patients. Methods UW-mRS was obtained analyzing EQ5-D-3 L at 180 days after any ÑANDU study, large prospective community-based study Chile....
Abstract: Steroids have been a cornerstone in renal transplant immunosuppression. New immunosuppressive drugs led to protocols using early steroid withdrawal or complete avoidance. A prospective protocol 23 pediatric (ages 2–14 yr) who received decreasing doses stopping at day 7 post‐Tx, FK, and MMF were compared with CsA, AZT, historically matched steroid‐based control group. Basiliximab was used two doses. Anthropometric, biochemical variables, AR rates, CMV infection evaluated Student’s...
To assess the relationship between early tobacco and alcohol use risk of marijuana consumption among schoolchildren.A cross-sectional study comprising data from Fourth National Study on Drug Use in Chilean School Population (2001). There were studied 54,001 schoolchildren aged eight 20 years. Predictors self-reported (ever users), age at initiation and/or use, intensity use. The outcome was users versus never users) Poisson regression Weibull used for analysis.Lifetime prevalence high: 77%,...
Prevalence of hypertension in school age children and its association with obesityBackground: Hypertension is a frequently overlooked problem that an important cardiovascular risk factor.Aim: To determine the prevalence among children.Material Methods: Cross-sectional study 2980 aged 10 ± 2 years (48% females) from schools middle lower class Metropolitan Santiago.Blood pressure (BP) was measured sitting position on three occasions after rest period, using mercury sphygmomanometer appropriate...