A5052428019- Neuroendocrine Tumor Research Advances
- Lung Cancer Research Studies
- Neuroblastoma Research and Treatments
- Cell death mechanisms and regulation
- Cancer Mechanisms and Therapy
- Pancreatic and Hepatic Oncology Research
- MicroRNA in disease regulation
University of Iowa
2022-2023
University of Minnesota
2012
Gastroenteropancreatic neuroendocrine neoplasms (GEP NENs) are rare cancers consisting of carcinomas (NECs) and tumors (NETs), which have been increasing in incidence recent years. Few cell lines pre-clinical models exist for studying GEP NECs NETs, limiting the ability to discover novel imaging treatment modalities. To address this gap, we isolated tumor cells from cryopreserved patient NETs injected them into flanks immunocompromised mice establish patient-derived xenograft (PDX) models....
Gastroenteropancreatic neuroendocrine neoplasms (GEP NENs) are rare cancers consisting of carcinomas (NECs) and tumors (NETs), which have been increasing in incidence recent years. Few cell lines pre-clinical models exist for the study GEP NECs NETs, limiting ability to discover novel imaging treatment modalities. To address this gap, we isolated tumor cells from cryopreserved patient NETs injected them into flanks immunocompromised mice establish patient-derived xenograft (PDX) models. Two...