- Bone and Joint Diseases
- Bone Tumor Diagnosis and Treatments
- Osteoarthritis Treatment and Mechanisms
- Heterotopic Ossification and Related Conditions
- Cancer-related molecular mechanisms research
- Oral and Maxillofacial Pathology
- Cardiac, Anesthesia and Surgical Outcomes
- Traditional Chinese Medicine Studies
- RNA modifications and cancer
- Musculoskeletal synovial abnormalities and treatments
- Geochemistry and Geologic Mapping
- Hip and Femur Fractures
- Disaster Response and Management
- Metabolism and Genetic Disorders
- Medicinal Plant Pharmacodynamics Research
- Healthcare and Venom Research
- Safety and Risk Management
- Orthopaedic implants and arthroplasty
- Rheumatoid Arthritis Research and Therapies
- Epigenetics and DNA Methylation
- Ferroptosis and cancer prognosis
- Biochemical and Molecular Research
- Bone fractures and treatments
- Geochemistry and Elemental Analysis
- Mesenchymal stem cell research
Gansu University of Traditional Chinese Medicine
2008-2024
Gansu Provincial Hospital
2012-2024
Shanghai East Hospital
2024
Gansu Provincial Hospital of TCM
2011-2018
Abstract Purpose Guanylate binding protein 4 (GBP4) is induced by interferons and various cytokines has been recognized as functionally relevant in numerous types of human cancers. While the role GBP4 cancer preliminarily summarized, its correlation with antitumor immunity remains unclear requires further research. Methods First, a comprehensive pan-cancer analysis was conducted, focusing on GBP4’s expression patterns immunological functions. Subsequently, we explored correlations between...
Osteoarthritis (OA) is a degenerative disease of articular cartilage involving the entire joint tissue. Columbianetin (CBT) major active compound radix angelicae pubescentis, which used in treatment OA. This paper attempts to explore role CBT Lipopolysaccharides (LPS) was induce mouse chondrocytes ATDC5. The effect on cell viability ATDC5 cells with or without LPS induction determined by CCK-8 and LDH kits. inflammatory response evaluated using ELISA Apoptosis LPS-induced were examined TUNEL...
摘要:...
BACKGROUND Myositis ossificans (MO) is a rare disease involving the formation of bone outside musculoskeletal system. While surgical intervention main treatment approach, preventing recurrence and standardized rehabilitation are also crucial. Here, we present strategy to prevent MO. CASE SUMMARY A 28-year-old female patient was admitted for first time comminuted fracture left olecranon. However, incorrect postoperative resulted in development elbow joint stiffness with ectopic ossification,...
This study explores the correlation between knee osteoarthritis and musculoskeletal ultrasound manifestations based on changes in traditional Chinese medicine (TCM) syndrome types. The enrolled 104 patients with admitted to Gansu Provincial Hospital of TCM January 2019 2021. According principle differentiation treatment TCM, were divided into wind-cold-damp obstruction (n = 17), damp-heat accumulation 22), qi-stagnation blood stasis 31), liver kidney deficiency 34) degrees cartilage injury,...
To investigate the difference in expression of Ras-associated protein 1 (Rap1) necrotic and healthy areas non-traumatic osteonecrosis femoral head (NONFH) patients.Femoral tissue samples from 30 cases NONFH traumatic (TONFH) were collected after hip replacement surgery, respectively. No significant Association Research Circulation Osseous (ARCO) staging was found between TONFH groups ( Z=-0.769, P=0.442). In group, 8 patients ARCO stage IIIb, 10 IV, 12 V, while ground, 11 9 V. There 19 males...
As a benign tumor-like lesion of bone tissue, simple cyst (SBC) occurs frequently in adolescents and children. Involving all bones, SBC is usually found humerus, femur calcaneus. Because its association with thick bone, it often accompanied by pathological fracture. Its diagnosis problematic because insidious onset, slow progression unobvious clinical symptoms signs. It diagnosed along traumatism, fracture or abnormal gait. Venous occlusion currently commonly acceptable pathogenesis. A wide...