A5023170300- Phytochemistry and Biological Activities
- Sesame and Sesamin Research
- Gut microbiota and health
- Gene expression and cancer classification
- Plant tissue culture and regeneration
- Metabolomics and Mass Spectrometry Studies
- Natural product bioactivities and synthesis
- Soybean genetics and cultivation
- Plant Stress Responses and Tolerance
- Traditional Chinese Medicine Analysis
- Probiotics and Fermented Foods
- Phytochemicals and Antioxidant Activities
- Genetic Mapping and Diversity in Plants and Animals
- Plant Parasitism and Resistance
- Microbial Metabolites in Food Biotechnology
- GABA and Rice Research
- Plant Molecular Biology Research
- Seed and Plant Biochemistry
- Allelopathy and phytotoxic interactions
- Plant-derived Lignans Synthesis and Bioactivity
- Bioinformatics and Genomic Networks
- Polysaccharides and Plant Cell Walls
RIKEN Center for Sustainable Resource Science
2022-2024
Nihon University
2018-2024
Intermediate omics traits, which mediate the effects of genetic variation on phenotypic are increasingly recognised as valuable components evaluation. In particular, rhizosphere microbiota play a crucial role in plant health and productivity; however, their complex interactions with host genetics remain challenging to model. Although two-step modeling frameworks have been proposed integrate intermediate traits into phenotype prediction, existing approaches do not incorporate nonlinear...
Three iridoids (lamalbid (I1), sesamoside (I2) and shanzhiside methyl ester (I3)) seven polyphenols (cistanoside F (P1), chlorogenic acid (P2), pedalitin-6-O-laminaribioside (P3), pedaliin (P4), isoacteoside (P6), pedalitin (P7) martynoside (P8)) were identified in young sesame leaves (Sesamum indicum L.) other than the acteoside (P5) reported previously. P3 was a new compound, I1, I3, P2 P8 found species of Sesamum for first time. HPLC analyses revealed that compounds I1 (0.29–1.75% dry...
Abstract Sesame (Sesamum indicum L.) plants contain large amounts of acteoside, a typical phenylethanoid glycoside (PhG) that exhibits various pharmacological activities. Although there is increasing interest in the biosynthesis PhGs for improved production, pathway remains to be clarified. In this study, we established sesame-cultured cells and performed transcriptome analysis methyl jasmonate (MeJA)–treated cultured identify enzyme genes responsible glucosylation acylation acteoside...
Phenylethanoid glycosides (PhGs), with a C6-C2 glucoside unit as the basic skeleton, are specialized (secondary) metabolites found in several medicinal plants. As PhGs exhibit various pharmacological activities, they expected to be used lead compounds drug discovery. However, mass-production systems have not yet been established even for acteoside, typical PhG that is widely distributed nature (more than 150 species). This review focuses on recent studies accumulation and distribution of...
A high-performance liquid chromatography (HPLC) method with relative molar sensitivity (RMS) based on 1 H quantitative NMR spectroscopy ( H-qNMR) has been developed for food ingredients such as acteoside (verbascoside) and pedaliin (pedalitin-6- O -glucoside) without requiring authentic identical standards the reliable analytical methods. This is used methyl 4-hydroxybenzoate (MHB) an alternative reference standard. Each RMS also calculated from ratio of each analyte's absorption coefficient...
<title>Abstract</title> High-dimensional multi-omics microbiome data plays an important role in elucidating microbial communities’ interactions with their hosts and environment critical diseases ecological changes. Although Bayesian clustering methods have recently been used for the integrated analysis of data, no method designed to analyze has proposed. In this study, we propose a novel framework called integrative stochastic variational variable selection (I-SVVS), which is extension...
The localization of acteoside and its precursors in different organs sesame plant (Sesamum indicum L.), including roots, stems (epidermis, cortex, stele), leaves (blades petioles), flower petals, seeds (immature mature) was investigated. highest content found leaf blades (12.3% dry weight), followed by petioles (3.1%) petals (2.7%) at a trace levels or not detected other organs. In contrast, the known acteoside, cinnamate, p-coumarate, caffeate, tyramine, tyrosol, salidroside,...
The role of the gut microbiota in gut-brain axis has attracted attention recent years. Some produces γ-aminobutyric acid (GABA), a major inhibitory neurotransmitter mammals,
Soybean (Glycine max) is a leguminous crop cultivated worldwide that accumulates high levels of isoflavones. Although previous research has often focused on increasing the soybean isoflavone content because estrogen-like activity dietary soy in humans, rapidly demand for as plant-based meat substitute raised concerns about excessive intake. Therefore, production isoflavone-free been anticipated. However, there have no reports an until now. Here, 2-hydroxyisoflavanone synthase (IFS), which...
Abstract High-dimensional multi-omics microbiome data plays an important role in elucidating microbial communities’ interactions with their hosts and environment critical diseases ecological changes. Although Bayesian clustering methods have recently been used for the integrated analysis of data, no method designed to analyze has proposed. In this study, we propose a novel framework called integrative stochastic variational variable selection (I-SVVS), which is extension high-dimensional...