C. Varma

ORCID: 0009-0004-4607-1215
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About
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Research Areas
  • Coronary Interventions and Diagnostics
  • Acute Myocardial Infarction Research
  • Cardiac Imaging and Diagnostics
  • Angiogenesis and VEGF in Cancer
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Cardiac electrophysiology and arrhythmias
  • Cardiac pacing and defibrillation studies
  • Cardiac Arrhythmias and Treatments
  • Lipoproteins and Cardiovascular Health
  • Venous Thromboembolism Diagnosis and Management
  • Cardiovascular and Diving-Related Complications
  • Congenital Heart Disease Studies
  • Cardiovascular Function and Risk Factors
  • Blood Pressure and Hypertension Studies
  • Aortic Disease and Treatment Approaches
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Retinal Diseases and Treatments
  • Infectious Aortic and Vascular Conditions
  • Vascular Procedures and Complications
  • Lipid metabolism and disorders
  • Cardiovascular Health and Disease Prevention
  • Adipokines, Inflammation, and Metabolic Diseases
  • Psychological and Temporal Perspectives Research
  • Potassium and Related Disorders
  • Cerebrovascular and Carotid Artery Diseases

Jawaharlal Institute of Post Graduate Medical Education and Research
2023

Sandwell & West Birmingham Hospitals NHS Trust
2009-2021

Birmingham City Hospital
2005-2020

Queen Elizabeth Hospital Birmingham
2012

University of Birmingham
2009-2012

Toronto General Hospital
2003-2005

University Health Network
2005

St George's, University of London
2000-2003

St George's Hospital
2000-2003

Royal Brompton Hospital
1996

Abstract. Jaumdally RJ, Goon PKY, Varma C, Blann AD, Lip GYH (City Hospital, Birmingham, United Kingdom). Effects of atorvastatin on circulating CD34+/CD133+/CD45− progenitor cells and indices angiogenesis (vascular endothelial growth factor the angiopoietins 1 2) in atherosclerotic vascular disease diabetes mellitus. J Intern Med 2010; 267 : 385–393. Background. Cardiovascular (CVD) remains a major cause morbidity mortality, especially presence diabetes, possibly because damage. Increased...

10.1111/j.1365-2796.2009.02151.x article EN Journal of Internal Medicine 2009-07-16

The aim of this study was to compare rates target lesion revascularisation (TLR) and total mortality between South Asians (SAs) White Europeans (WEs) following percutaneous coronary intervention (PCI).We followed a cohort 293 SAs 865 WEs patients admitted for elective or urgent PCI de novo lesions. For each patient, baseline cardiovascular risk factors angiographic data were obtained. Patients had long-term follow-up all-cause TLR.Patients up over median period 54 months (inter-quartile...

10.1111/j.1742-1241.2011.02776.x article EN International Journal of Clinical Practice 2011-11-17

Objective: To determine the effect of multisite pacing on left ventricular function. Design: Prospective observational study. Patients: 18 patients with heart failure a dilated poorly functioning ventricle (LV) and bundle branch block. Interventions: Pacing for 5 minutes in random order at right (RV) apex, RV outflow tract, mid posterolateral LV, apex LV simultaneously, tract simultaneously. The best achieved measurements RV, biventricular were compared. Main outcome measures: dimension,...

10.1136/heart.87.4.322 article EN Heart 2002-04-01

To evaluate reduction of door-to-balloon (DTB) time and its impact on in-hospital mortality high-risk infarct patients in a collaboration district general hospitals (DGH) with physician-to-patient model.Primary percutaneous coronary interventions (PPCI) short DTB offer benefit for ST-segment elevation myocardial infarction but literatures are conflicting this high- vs. low-risk patients. In unique model at Sandwell West Birmingham Hospitals, five interventional cardiologists provide 24-h...

10.1111/j.1742-1241.2009.02122.x article EN International Journal of Clinical Practice 2009-08-20

Paradoxical coronary artery embolism causing acute myocardial infarction in a young woman with factor V Leiden thrombophillia ABSTRACT is rare but under-diagnosed cause of (AMI) and requires high level clinical suspicion to make an early diagnosis.We describe the case who presented severe cough chest pain was subsequently found have paradoxical embolus right artery.Echocardiography showed patent foramen ovale (PFO) atrial septal aneurysm (ASA).The patient be heterozygous carrier mutation...

10.4997/jrcpe.2012.306 article EN The Journal of the Royal College of Physicians of Edinburgh 2012-09-05

Nonesterified fatty acids (NEFA) and insulin have been implicated in the pathogenesis of diabetes mellitus (Type 2 diabetes) coronary artery disease (CAD). We hypothesized that intracardiac levels NEFA within aortic root, sinus systemic venous would be different patients with atherosclerosis and/or diabetes. also studied metabolic cardiac response following percutaneous intervention (PCI).A total 67 subjects (42 males; mean age 60 +/- 11 years) were recruited, which three groups identified:...

10.1111/j.1365-2796.2009.02072.x article EN Journal of Internal Medicine 2009-02-16

VARMA, C., et al .: Comparison Between Biventricular Pacing and Single Site in Patients with Poor Ventricular Function: A Hemodynamic Study. pacing has been suggested as offering greater hemodynamic benefit than single site patients advanced heart failure left bundle branch block. This was tested using acute multisite pacing. Eighteen such were atrial‐sensed, ventricular paced random order for 5 minutes. The best achieved measure of cardiac output (CO), pulmonary capillary wedge pressure...

10.1046/j.1460-9592.2003.00093.x article EN Pacing and Clinical Electrophysiology 2003-02-01

The aim of this study was to audit the management hyperlipidaemia in a cohort 206 consecutive patients, with known or suspected coronary artery disease, referred for diagnostic angiography. association lipid subfraction values presence and extent disease explored identify indices greatest potential value hospital cardiologist, secondary prevention. Patients were questioned about previous tests performed, advice received treatment prescribed. Referral letters notes reviewed documentation...

10.1093/oxfordjournals.eurheartj.a014748 article EN European Heart Journal 1996-11-01

Abstract Introduction The Genous stent is a bare metal (BMS) together with technique of capturing endothelial progenitor cells. successor the cell (EPC) stent, COMBO combines this drug eluting polymer. current studies showed promising results however additional value EPC in overcoming neointimal hyperplasia has yet to be proven. Purpose This study sought evaluate efficacy and safety compared BMS patient population low risk for restenosis. Methods TRIAS-LR was an investigator-initiated,...

10.1093/ehjci/ehaa946.2545 article EN European Heart Journal 2020-11-01

Abstract Background One of the major long-term disadvantages percutaneous coronary intervention (PCI) remains in-stent restenosis and need for repeat revascularisation. The polymer-regulated delivery cytotoxic or cytostatic drugs, on drug-eluting stents (DES), impede natural healing response damaged vessel wall. In animals, endothelial progenitor cells (EPCs) beneficially influence repair wall after damage by stent placement. It is hypothesized that immobilisation EPCs differentiate into a...

10.1093/eurheartj/ehz748.1111 article EN European Heart Journal 2019-10-01

A computer system to calculate left ventricular (LV) cavity dimension (LVD) from M-mode echocardiography, and LV pressure (LVP) micromanometer tipped catheter simultaneously was developed. An operator marked the posterior wall septal endocardial borders, LVP tracing, reference points on a scanned bitmap image of echocardiogram trace. Individual lines were automatically recognized in bitmap, values at individual recalculated missing data interpolated. The time functions LVD constructed....

10.1109/cic.1999.825988 article EN 2003-01-20

Background As a result of increased cost and bleeding concerns, older patients receive abciximab during percutaneous coronary intervention (PCI) less often than younger patients. Objective The aim this was to evaluate the safety efficacy in adults undergoing PCI. Design Retrospective, observational single centre cohort study. Methods British Cardiovascular Intervention Society (BCIS) database used establish impact people with advanced age (≥ 75 years) on in-hospital ischaemic events...

10.1111/ijcp.12702 article EN International Journal of Clinical Practice 2015-07-23

Desmoplastic fibroma is a rare benign bone tumor primarily seen in long bones and mandible. Our case was of 10-year-old with painless infra orbital swelling for which she underwent excision under general anesthesia reconstruction plating iliac crest grafting. By its unique clinical presentation diagnostic challenges encountered managing this condition, report expands our understanding the disease’s management, it guides future therapeutic decision-making similar pediatric cases.

10.1177/27325016231196487 article EN FACE 2023-08-27
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