A5074613980- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Cardiac electrophysiology and arrhythmias
- Mechanical Circulatory Support Devices
- Advanced MRI Techniques and Applications
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Cerebrovascular and Carotid Artery Diseases
- Angiogenesis and VEGF in Cancer
- Vascular Procedures and Complications
- Cardiac Arrest and Resuscitation
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac and Coronary Surgery Techniques
- Advanced X-ray and CT Imaging
- Cardiac Arrhythmias and Treatments
- Cardiovascular Function and Risk Factors
- Cardiac, Anesthesia and Surgical Outcomes
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Disease and Adiposity
- Aortic aneurysm repair treatments
- Radiomics and Machine Learning in Medical Imaging
- Peripheral Artery Disease Management
- Photoacoustic and Ultrasonic Imaging
- Ultrasound and Hyperthermia Applications
Amsterdam University Medical Centers
2018-2025
Vrije Universiteit Amsterdam
2019-2025
University of Amsterdam
2009-2024
Amsterdam UMC Location Vrije Universiteit Amsterdam
2019-2024
Amsterdam Neuroscience
2021-2024
Institute of Cardiology
2009-2022
Amsterdam UMC Location University of Amsterdam
2008-2017
To describe patients with a distinct electrocardiogram (ECG) pattern without ST-segment elevation in the presence of an acute occlusion proximal left anterior descending (LAD) artery.Single-centre observational study.Patients wall myocardial infarction who were referred for primary percutaneous coronary intervention (PCI) between 1998 and 2008.We identified static, ECG LAD artery during urgent angiography before PCI. Of 1890 underwent PCI artery, we could identify 35 (2%) this pattern. The...
Early P2Y
AimsThe purpose of this study was to evaluate the GenousTM endothelial progenitor cell capturing stent vs. Taxus Liberté paclitaxel-eluting in patients with de novo coronary lesions a high-risk restenosis.
Patients with acute coronary syndrome who present initially ST-elevation on the electrocardiogram but, subsequently, show complete normalization of ST-segment and relief symptoms before reperfusion therapy are referred to as transient elevation myocardial infarction (STEMI) pose a therapeutic challenge. It is unclear what optimal timing revascularization for these patients whether they should be treated STEMI-like or non-ST-segment (NSTEMI)-like invasive approach. The aim study determine...
The European Society of Cardiology guidelines recommend risk stratification with limited clinical parameters such as left ventricular (LV) function in patients chronic coronary syndrome (CCS). Machine learning (ML) methods enable an analysis complex datasets including transthoracic echocardiography (TTE) studies. We aimed to evaluate the accuracy ML using and TTE data predict all-cause 5-year mortality CCS compare its performance traditional scores.
The relationship between fractional flow reserve (FFR), resting full-cycle ratio (RFR), instantaneous wave-free (iFR), distal pressure/aortic pressure (Pd/Pa), and plaque burden as well phenotype requires further elucidation. In this single-center cohort study, patients with suspected coronary artery disease who underwent invasive angiography, including routine hyperemic (FFR) nonhyperemic (Pd/Pa iFR or RFR) interrogation computed tomography angiography were prospectively enrolled. Computed...
ABSTRACT Background Revascularization decision‐making for saphenous vein grafts (SVGs) relies on angiographic lesion severity estimation, as studies fractional flow reserve (FFR) detecting ischemia in SVGs are scarce. Aims To compare FFR and quantitative coronary angiography (QCA) of against myocardial perfusion imaging (MPI) to establish an optimal threshold SVGs. Methods This cross‐sectional registry study included symptomatic patients with prior artery bypass grafting who underwent...
ABSTRACT Background The relationship between height differences related to graft anatomy and physiological pressure indices in coronary bypass grafts has not been studied. We sought study the impact of hydrostatic on fractional flow reserve (FFR) saphenous vein (SVGs). Methods Included were 66 symptomatic patients (76 SVGs) with prior artery grafting who underwent computed tomography angiography (CCTA) preceding invasive FFR interrogation ≥ 1 SVGs. course excursion reconstructed based CCTA...
Abstract Background In the setting of primary percutaneous coronary intervention, patients with a chronic total occlusion in non-infarct related artery were recently identified as high-risk subgroup. It is unclear whether ST-elevation myocardial infarction should undergo additional intervention on top optimal medical therapy shortly after intervention. Possible beneficial effects include reduction adverse left ventricular remodeling and preservation global function improved clinical outcome...
Cardiogenic shock (CS) complicating acute myocardial infarction (AMI) is associated with high morbidity and mortality. Our study aimed to gain insights into patient characteristics, outcomes treatment strategies in CS patients. Patients who underwent percutaneous coronary intervention (PCI) between 2017 2021 were identified a nationwide registry. Data on medical history, laboratory values, angiographic features retrospectively assessed. A total of 2328 patients mean age 66 years whom 73%...
Same-day discharge (SDD) in patients undergoing percutaneous coronary intervention (PCI) of a chronic total occlusion (CTO) is appealing because the increased patient comfort. However, data on SDD following large-bore vascular access are scarce.
Abstract Background Mortality rates in patients with cardiogenic shock complicating acute myocardial infarction (AMICS) remain high despite advancements AMI care. Our study aimed to investigate the impact of prehospital symptom duration on prognosis AMICS and those receiving mechanical circulatory support (MCS). Methods results We conducted a retrospective cohort data registered Netherlands Heart Registration. A total 1,363 who underwent percutaneous coronary intervention between 2017 2021...
Aim of this study was to investigate the diagnostic accuracy conventional electrocardiogram (ECG) algorithm [ST-segment elevation (STE) in lead III exceeding that II combined with ST-segment depression I or aVL] for identification infarct-related artery (IRA) a large cohort patients undergoing primary percutaneous coronary intervention (PCI) inferior wall STE myocardial infarction (STEMI). We included 1131 STEMI, who underwent PCI between 2000 and 2007 whom pre-procedural 12-lead ECG...
Abstract Objectives This study aimed to investigate the performance of computed tomography derived fractional flow reserve based interactive planner (FFR CT planner) predict physiological benefits percutaneous coronary intervention (PCI) as defined by invasive post‐PCI FFR. Background Advances in FFR technology have enabled simulation hyperemic pressure changes after virtual removal stenoses. Methods In 56 patients (63 vessels) measurements before and PCI were obtained was calculated using...
Coronary flow capacity (CFC) integrates quantitative hyperaemic myocardial blood (hMBF) and coronary reserve (CFR) to comprehensively assess physiological severity of artery disease (CAD). This study evaluated the effects revascularization on CFC as assessed by serial [15O]H2O positron emission tomography (PET) perfusion imaging.A total 314 patients with stable CAD underwent PET imaging at baseline after changes in hMBF, CFR, 415 revascularized vessels. Using thresholds for ischaemia normal...
The Heart Team is a multidisciplinary meeting for shared decision-making in cardiology and cardiothoracic surgery. A quality improvement project to optimise the was initiated after merger of cardiac centres Amsterdam University Medical Centre.