- Advanced Measurement and Metrology Techniques
- Advanced machining processes and optimization
- Neuroinflammation and Neurodegeneration Mechanisms
- Advanced Surface Polishing Techniques
- Advanced Numerical Analysis Techniques
- Cardiac Ischemia and Reperfusion
- Manufacturing Process and Optimization
- Renal and Vascular Pathologies
- Alcoholism and Thiamine Deficiency
- Industrial Vision Systems and Defect Detection
- Immune cells in cancer
- Fault Detection and Control Systems
- Smart Grid and Power Systems
- Neurological diseases and metabolism
- Structural Health Monitoring Techniques
- Evaluation and Optimization Models
- Organ Donation and Transplantation
- Laser and Thermal Forming Techniques
- Structural Engineering and Vibration Analysis
- Advanced Data Storage Technologies
- Evaluation Methods in Various Fields
- Energy Load and Power Forecasting
- Prion Diseases and Protein Misfolding
- Advanced Decision-Making Techniques
- Asphalt Pavement Performance Evaluation
Capital Medical University
2023-2025
Chinese Institute for Brain Research
2024
Chang'an University
2019-2024
Stanford University
2024
Aero Engine Corporation of China (China)
2015-2021
Toronto Metropolitan University
2021
Xi'an University of Technology
2021
Xi'an Jiaotong University
2017
Wuhan National Laboratory for Optoelectronics
2010-2013
Huazhong University of Science and Technology
2013
Background Melatonin protects against ischaemic stroke in diabetic animal models, though the mechanisms involving brain and peripheral immune responses remain underexplored. We aimed to clarify how melatonin interacts with these protect mice. Methods Type 1 diabetes mellitus (T1DM) was induced mice using streptozotocin. RNA sequencing of tissue blood mononuclear cells (PBMCs) performed 24 hours poststroke. Inflammatory were evaluated 72 after ischaemia/reperfusion. Results reduced infarction...
Abstract Background Acute ischemic stroke (AIS) complicating an acute myocardial infarction (AMI) is not uncommon, but can severely worsen the clinical prognosis. This study aimed to investigate whether remote conditioning (RIC) could provide benefits patients with AIS AMI. Methods Subjects AMI were recruited in this double-blind, randomized, controlled trial; assigned RIC and sham groups; respectively underwent twice daily for 2 weeks. All subjects received standard medical therapy. The...
Abstract Background Angong Niuhuang Wan (AGNHW, 安宫牛黄丸), is a classical medicinal formula in Traditional Chinese Medicine (TCM) that has been appreciated for its neuroprotective properties ischemic cerebral injuries, yet intricate mechanisms remain only partially elucidated. Aims This study leverages advanced Mass cytometry (CyTOF) to analyze AGNHW's multifaceted immunomodulation effects in‐depth, emphasizing previously underexplored areas. Results AGNHW mitigated monocyte‐derived macrophages...
Background: Stroke-Induced Immunodepression (SIID) is characterized by apoptosis in blood immune populations, such as T cells, B NK and monocytes, leading to the clinical presentation of lymphopenia. Disulfidptosis a novel form programmed cell death accumulating disulfide bonds cytoplasm, resulting cellular dysfunction eventual death. Objective: In this study, we investigated association between disulfidptosis stroke analyzing gene sequencing data from peripheral samples patients. Methods:...
Abstract This perspective article delineates the significant role of hypoxic pockets—localized, transient reductions in cerebral oxygenation—and their implications for stroke neuroprotection strategies. It posits that preconditioning and postconditioning, through interventions like isoflurane, exercise, remote limb ischemic conditioning, can mitigate these pockets, potentially protecting brain against events. These strategies exploit brain's intrinsic adaptive capabilities to resist damage,...
The machining of complex curved surface is a highly process. Cutting load and the various changes tool spindle vector are important causes which restrict precision efficiency machining. This paper presents an analysis method techniques about based on advanced theory, constitutes relationship among cutting tools, parameters through analyzing affect factors force. Optimize according to results. Finally using field process validated that efficacious.
To study the vehicle–bridge interaction (VBI) of highway bridges under seismic excitation, a couple analysis method based on Ansys is proposed. The 1/2 vehicle model and space beam element were established to analyze VBI response Lanzhou Xiaoshagou bridge. self-excited excitation system represented by road surface irregularity randomness, while external an earthquake. impact types, direction, intensity, speed, bridge vibration coupling during earthquake thoroughly analyzed. results reveal...
Exposure to particulate matter 2.5 (PM2.5) is detrimental multiple organ systems. Given the factor that aging also alters cellularity and response of immune system dysfunction hypothalamic‐pituitary‐adrenal, ‐gonad ‐thyroid axes, it imperative investigate whether chronic exposure PM2.5 interacts with in these aspects. In this study, two‐months‐old Sprague–Dawley rats were exposed real world for 16 months. diminished relative numbers CD4 + T cells CD8 increased number B peripheral blood male...
With data amount growing at an ever increasing rate, file system, as the basis of management, its functionality and content are becoming more complex. Thus system is forced to be upgraded constantly, in order satisfy demands. However, reinvention new systems always a high-cost task. Although there frameworks such User-space File System that may help speeding up development process, ease pain deploying functions, they also bring significant overhead, especially when operation frequency fairly...
Surface defects caused by damage or corrosion are major factor in petrochemical pressure vessels and line pipes failure. The characteristic size of typical surface defect is from micron to submillimeter which belongs mesoscopic scale, leading difficulties for inspection evaluation. instrumented indentation method has widely used the characterization micro-zone mechanical behavior could be effective analysis. This paper aims at investigating correspondence between experimental results...
A kind of Neural networks Control algorithm has been used for RF-exited CO2 Laser. Through the simulation, related control parameters are tested and verified. The results verify good output performances.
Load forecasting (LF) is of great significance for effective operation, utilization, safety and reliability the modern electric power systems. can be categorized into very short term, short-term, medium-term, long-term forecasts, depending on which time scale concerned. The term load (STLF) plays an increasingly important role in achieving a more efficient, reliable safe system. Its outputs are indispensable inputs generating scheduling, system security assessment dispatch. In era smart grid...
Aiming at the problem of inaccurate prediction fatigue crack propagation due to uncertain factors, a method based on Dynamic Bayesian Network (DBN) is proposed in this paper. A simulation model established finite element analysis software ABAQUS. The Paris formula combined with model(FEM) establish state equation. And constructed parameters defined FEM. strain sensors are adopted monitor propagation. data and length fitted into function construct observation model, particle filter algorithm...