Jian Yang

ORCID: 0000-0003-4062-4646
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About
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Research Areas
  • Advanced Data Storage Technologies
  • Parallel Computing and Optimization Techniques
  • Advanced MRI Techniques and Applications
  • Radiation Dose and Imaging
  • Cardiac Ischemia and Reperfusion
  • Neonatal and fetal brain pathology
  • Cloud Computing and Resource Management
  • Caching and Content Delivery
  • Anesthesia and Neurotoxicity Research
  • Ultrasound and Hyperthermia Applications
  • Air Quality and Health Impacts
  • Atmospheric chemistry and aerosols
  • Acute Ischemic Stroke Management
  • Liver Disease Diagnosis and Treatment
  • Atomic and Subatomic Physics Research
  • Cancer-related molecular mechanisms research
  • Neuroinflammation and Neurodegeneration Mechanisms
  • IoT and Edge/Fog Computing
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Lung Cancer Diagnosis and Treatment
  • Advanced X-ray and CT Imaging
  • Cerebrospinal fluid and hydrocephalus
  • Coronary Interventions and Diagnostics
  • Neurogenesis and neuroplasticity mechanisms
  • Ultrasound Imaging and Elastography

University of Science and Technology of China
2009-2025

East China Normal University
2024-2025

Chongqing Medical University
2021-2025

Jiaozuo University
2025

Hebei Medical University
2024

Beijing Luhe Hospital Affiliated to Capital Medical University
2017-2024

First Affiliated Hospital of Xi'an Jiaotong University
2015-2024

Third Hospital of Hebei Medical University
2024

First Affiliated Hospital Zhejiang University
2024

State Key Laboratory of Chemical Engineering
2024

Next-generation non-volatile memories (NVMs) promise DRAM-like performance, persistence, and high density. They can attach directly to processors form main memory (NVMM) offer the opportunity build very low-latency storage systems. These high-performance systems would be especially useful in large-scale data center environments where reliability availability are critical. However, providing NVMM is challenging, since latency of replication overwhelm low that should provide. We propose Mojim,...

10.1145/2694344.2694370 article EN 2015-03-03

Accurately estimating forest carbon sink and exploring their climate-driven mechanisms are critical to achieving neutrality sustainable development. Fewer studies have used machine learning-based dynamic models estimate sink. The in Shangri-La yet be explored. In this study, a genetic algorithm (GA) was optimize the parameters of random (RF) establish intensity (CSI) Pinus densata analyze combined effects multi-climatic factors on CSI. We found that (1) GA can effectively improve estimation...

10.1038/s41598-024-84258-7 article EN cc-by-nc-nd Scientific Reports 2025-01-02

Circular RNAs (circRNAs) have been demonstrated to act as microRNA (miRNA) sponges and they play important roles in regulating gene expression through a circRNA-miRNA-gene pathway. The specific of circRNAs the pathogenesis cerebral ischemia, however, are still unclear. Thus, aim this study is determine circRNA profiles ischemic brain after stroke, which was induced by 45 min transient middle artery occlusion (MCAO). results from microarrays revealed that 1027 were significantly altered 48...

10.18632/oncotarget.21238 article EN Oncotarget 2017-09-23

Background Limb remote ischemic preconditioning ( RIPC ) protects against brain injury induced by stroke, but the underlying protective mechanisms remain unknown. As hypoxia inducible factor 1α HIF ‐1α) is neuroprotective in stroke and mediates neuroinflammation, we tested hypothesis that ‐1α a key of mediating inflammation. Methods Results Stroke was transient middle cerebral artery occlusion rats, conducted both hind limbs. The mRNA examined quantitative reverse transcription polymerase...

10.1161/jaha.117.007589 article EN cc-by-nc-nd Journal of the American Heart Association 2018-02-25

Scalable server-grade non-volatile RAM (NVRAM) DIMMs became commercially available with the release of Intel's Optane DIMM. Recent studies on DIMM systems unveil discrepant performance characteristics, compared to what many researchers assumed before product release. Most these focus system software design and analysis. To thoroughly analyze source this discrepancy facilitate real-NVRAM-aware architecture design, we propose a framework that characterizes models DIMM's microarchitecture. Our...

10.1109/micro50266.2020.00049 article EN 2020-10-01

Patients with Crohn's disease (CD) commonly experience malnutrition. The Global Leadership Initiative on Malnutrition (GLIM) criteria, a novel approach to assessing malnutrition, has been validated in some diseases. However, there are limited studies CD patients. This study aimed investigate the applicability and effectiveness of simplified GLIM criteria for evaluating nutritional status patients disease. Additionally, it sought evaluate correlation between malnutrition defined by clinical...

10.3389/fnut.2024.1414124 article EN cc-by Frontiers in Nutrition 2025-01-07

Background: The increase in major adverse cardiovascular events (MACE) patients with diabetes after primary percutaneous coronary intervention (pPCI) is significantly correlated the admission blood glucose (ABG). However, it unclear whether ABG non-diabetic related to MACE pPCI. We aimed explore relationship between and in-hospital ST-segment elevation myocardial infarction (STEMI) Killip class I treated Methods: Chinese STEMI pPCI Registry (NCT04996901) enrolled 5586 undergoing from January...

10.59958/hsf.8145 article EN The Heart Surgery Forum 2025-01-20

Different studies have shown that values and motivation predict physical activity, but no study has tested how may interact to activity. Specifically, the present research aimed test toward activity measured within SDT could global among Chinese sports science students. The indirect effects of openness change self-transcendence on predicting through autonomous were significant. These results help us understand highly abstract psychological constructs such as influence motivation. Studying...

10.1371/journal.pone.0316731 article EN cc-by PLoS ONE 2025-02-24

Remote ischemic preconditioning (RIPC) of a limb has been reported to protect against stroke. Our previous results demonstrated that the RIPC-mediated neuroprotection is associated with alterations in circulating immune cell populations. Here, we evaluated effect spleen, largest reservoir cells, on Noninvasive RIPC was achieved by four repeated cycles 5-min blood flow constriction hindlimbs using tourniquet. The and spleens were collected before 1 h 3 days after analyze spleen correlation...

10.1186/s12974-018-1190-9 article EN cc-by Journal of Neuroinflammation 2018-05-28

The Circle of Willis (CoW) is an important collateral pathway the cerebral blood flow. An experimental study flow (CBF) distribution in different anatomical variations may help to a better understanding mechanism CoW. in-vitro test rig was developed simulate physiological Ten were considered this study, include set degrees stenosis L-ICA and occlusion coexist with common variations. Volume rates efferent arteries pressure signals at end communicating each case recorded. Physiological...

10.1186/1475-925x-14-s1-s10 article EN cc-by BioMedical Engineering OnLine 2015-01-01

The aim of this study is to provide better insights into the cerebral perfusion patterns and collateral mechanism circle Willis (CoW) under anatomical pathological variations. In current study, a patient-specific three-dimensional computational model CoW was reconstructed based on computed tomography (CT) images. Carreau applied simulate non-Newtonian property blood. Flow distributions in five common variations coexisting with different degrees stenosis right internal carotid artery (RICA)...

10.1186/s12938-015-0105-6 article EN cc-by BioMedical Engineering OnLine 2015-11-25

Limb remote ischemic preconditioning (RIPC) has been proven to alleviate stroke injury in young rats, but its protective effect and mechanism aged rats are still unclear. Hypoxia-inducible factor (HIF) is one of the important markers stroke, high expression plays an role pathogenesis stroke. In this study, we tested hypothesis that RIPC could regulate HIF, leading reduced inflammatory responses rats. Stroke was induced by transient middle cerebral artery occlusion (MCAo) conducted both hind...

10.3389/fnagi.2020.00054 article EN cc-by Frontiers in Aging Neuroscience 2020-03-10

This study evaluated the separate and combined associations of physical activity obesity with blood lipids in Chinese adults without diabetes. Data 17,535 participants aged 18 to 78 years old were collected. Physical was categorized as inactive (low) or active (moderate high) according International Activity Questionnaire. Linear logistic regression analyses performed investigate lipid-related indices. Compared physically participants, had higher triglyceride (TG) level, lower high-density...

10.1186/s12944-019-0987-6 article EN cc-by Lipids in Health and Disease 2019-02-12
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