A5102893512- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Immune cells in cancer
- Immunotherapy and Immune Responses
- Cardiovascular Function and Risk Factors
- Extracellular vesicles in disease
- Advanced MRI Techniques and Applications
- Cerebrovascular and Carotid Artery Diseases
- Phagocytosis and Immune Regulation
- Advanced X-ray and CT Imaging
- Hemodynamic Monitoring and Therapy
- Cancer Mechanisms and Therapy
- Abdominal Trauma and Injuries
- Congenital Anomalies and Fetal Surgery
- Glycogen Storage Diseases and Myoclonus
- Cytokine Signaling Pathways and Interactions
- Cardiac Valve Diseases and Treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Experimental Learning in Engineering
- Abdominal vascular conditions and treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Cardiovascular Health and Disease Prevention
- Peroxisome Proliferator-Activated Receptors
- Vascular Anomalies and Treatments
- Phytochemical compounds biological activities
Dalian Medical University
2025
Second Affiliated Hospital of Dalian Medical University
2025
Beijing Institute of Technology
2025
University of Chinese Academy of Sciences
2024
China Pharmaceutical University
2023-2024
Shanghai Changning Maternity and Infant Health Hospital
2024
First Affiliated Hospital of Zhengzhou University
2024
Shanghai Sixth People's Hospital
2019-2023
First People’s Hospital of Zunyi
2021-2022
Sheehan Medical (United States)
2022
In the injured liver, hepatic stellate cells (HSCs) secrete many different cytokines, recruit lymphocytes, and thus participate actively in pathogenesis of liver disease. Little is known role HSCs immune responses. this study, isolated from C57BL/10 (H2b) mice were found to express scant key surface molecules quiescent stage. Activated major histocompatibility complex class I, costimulatory molecules, produce a variety cytokines. Stimulation by interferon γ (IFN–γ) or activated T enhanced...
Objectives: To assess the effectiveness of transcatheter aortic valve replacement (TAVR) on electrocardiographic remodeling in patients with severe stenosis (AS), and identify its influencing factors. Methods: A cohort study was conducted a confirmed diagnosis AS who successfully underwent TAVR at Second Affiliated Hospital Dalian Medical University between June 2018 March 2023. Data, including standard 15-lead electrocardiograms echocardiograms, were collected before operation, 1 week after...
We designed to investigate the effects of down-regulating tumor susceptibility gene 101 (TSG101) on proliferation and apoptosis human breast cancer MCF-7 cell line, role MAPK/ERK signal pathway in this process. The siRNA against TSG101 was transfected into line using Lipofectamine 2000. After knockdown, cells measured by MTT assay. cycle distribution were examined flow cytometry while migration a transwell protein level p-ERK further assessed immunofluorescence western blotting. Our results...
Extracellular vesicles (EVs) are mediators between cancer cells and other types of cells, such as tumor-associated macrophages (TAMs), in the tumor microenvironment. EVs can remodel microenvironment regulate progression. However, underlying molecular mechanism these interactions remains unclear. First, we explored effect TAMs on survival prognosis patients with ovarian cancer. Next, isolated derived from (OV-EVs) through ultracentrifugation analyzed capacity OV-EVs to macrophage polarization...
Highway engineering construction is a complex multi-objective management project, and the traditional task approach has been difficult to cope with uniqueness of highway management. In order improve efficiency in engineering, study proposes construct model using particle swarm harmony search algorithms for First all, first explores indexes constructs functional relationship according selected indexes. Then algorithm used optimize database harmonic algorithm, can be based on optimized find...
To investigate the optimal measurement site of coronary-computed tomography angiography-derived fractional flow reserve (FFR CT ) for assessment coronary artery disease (CAD) in whole clinical routine practice.This retrospective multicenter study included 396 CAD patients who underwent angiography, FFR , and invasive FFR. was measured at 1 cm -1 cm), 2 -2 3 -3 4 -4 cm) distal to stenosis, respectively. ≤0.80 were defined as lesion-specific ischemia. The diagnostic performance detect ischemia...
Massive Open Online Courses (MOOC), is a web-based platform providing online course resources for thousands of participants to learn effectively and collaboratively. With the development mobile devices wireless networks, MOOC widely used in field learning (ML) recent years, especially U.S European countries, which brings learners more flexibility convenience. Although use still its infancy China, there have been some success stories schools. This paper we will describe named WeCast developed...
The CXCR4/CXCL12 chemokine axis demonstrates significant potential in the treatment of inflammatory bowel disease (IBD) due to its crucial roles and immune responses. Modulating pathway can be an effective therapeutic approach ameliorate state IBD. In this study, a novel series meta-dibenzyl amide derivatives were designed synthesized based on lead compound AMD3100 structurally modified derivatives. Both vitro vivo assays conclusively established that these compounds exhibited potent CXCR4...
<title>Abstract</title> Background Extracellular vesicles involve in the interplay between cancer cells and other (including tumor associated macrophages) surrounding microenvironment, to remodel microenvironment subsequently regulate progression. However, underlying molecular mechanism of these complicated crosstalk are still unclear. Methods Firstly, we explored effect tumor-associated macrophages (TAM) on survival prognosis among patients with ovarian cancer. Then isolated extracellular...
ABSTRACT Background and Aims Metabolic dysfunction‐associated steatotic liver disease (MASLD) presents a high incidence globally is major cause of cirrhosis hepatocellular carcinoma, lacking efficient interventions. Patients with MASLD exhibit exceeded serum levels palmitic acid (PA). However, the association between PA remains obscure. Methods Gene expression omnibus dataset analysis, western blotting, mRNA‐sequencing, RT‐qPCR, click chemistry‐immunoprecipitation‐immunofluorescence system,...
The stress relationship between the artifical knee-joints of same pairing and crossed was studied by contrastive contact analysis finite element simulation in different angles conditions. service lives were based on above result Archard wear design calculation theory to expand application existing artificial knee-joints. shows that, maximal stresses are more than those pairing, types are, obvious growths are. life knee-joint 3/3 is 28.42 years, 3/2.5 3/4 27.08 years 25.76 respectively.
We investigated the factors associated with serum muscle enzyme elevation in patients Sheehan's syndrome. A total of 48 who were newly diagnosed syndrome included and divided into 3 groups: Group 1, creatine kinase (CK) ≥ 1000 U/L; 2, 140 < CK 3, ≤ U/L. Differences enzymes, electrolytes, blood glucose hormones compared among groups. Spearman correlation analysis multiple linear regression performed on enzymes other variables. Four 1 underwent electromyography. Fourteen, 26 8 respectively....
Left ventricular diastolic dysfunction (LVDD) can be affected by many factors, including epicardial adipose tissue (EAT), obesity and type-2 diabetes mellitus (T2DM). The aim of this study was to establish validate an easy-to-use nomogram that predicts the severity LVDD in patients with T2DM. This is a retrospective 84 consecutive subjects T2DM admitted Endocrinology Department, First People's Hospital Zunyi City between January 2015 October 2020. Several echocardiographic characteristics...
This paper presents VerteMeasure, an efficient system designed for measuring human spinal bone impedance. VerteMeasure is capable of discerning the type and detecting if any abnormal issues like bleeding occur during surgery. The screwdriver-like device includes a main control system, screw-like probe tips connected to electrode terminals, easy-to-use handles. provides switch signal current source circuit generate excitation terminals. voltage enters through response terminals transmitted...