A5101825348- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Gut microbiota and health
- Advanced X-ray and CT Imaging
- Advanced MRI Techniques and Applications
- Acute Myocardial Infarction Research
- Coronary Artery Anomalies
- Radiation Dose and Imaging
- Ultrasound in Clinical Applications
- Clostridium difficile and Clostridium perfringens research
- Venous Thromboembolism Diagnosis and Management
- Pancreatic and Hepatic Oncology Research
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Disease and Adiposity
- Parathyroid Disorders and Treatments
- Pancreatitis Pathology and Treatment
- Vascular anomalies and interventions
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Gastrointestinal motility and disorders
- Parasites and Host Interactions
- Cardiac Valve Diseases and Treatments
- Microscopic Colitis
- Nosocomial Infections in ICU
- Cardiovascular Function and Risk Factors
- Reservoir Engineering and Simulation Methods
Nanjing University
2015-2025
The Seventh Affiliated Hospital of Sun Yat-sen University
2025
Sun Yat-sen University
2025
Nanjing General Hospital of Nanjing Military Command
2014-2024
Nanjing Medical University
2014-2024
Soochow University
2024
Renmin Hospital of Wuhan University
2024
First Affiliated Hospital of Soochow University
2024
Wuhan University
2024
Chongqing Medical University
2021-2024
We aim to characterize the fungal microbiota in intestinal mucosa and feces patients with Crohn's disease (CD).Fungi represent a diverse microbial community human intestine might play role pathogenesis of CD; however, little is known about structure composition especially adhering CD patient.Nineteen active 7 healthy individuals were recruited this study. The mucosa-associated fecal microbiotas analyzed using culture-independent fingerprint techniques.The richness diversity significantly...
Abstract Introduction Dysbiosis of intestinal microbiota likely plays an important role in the development gut-derived infections, making it a potential therapeutic target against sepsis. However, experience with fecal transplantation (FMT) treatment sepsis and knowledge underlying mechanisms are extremely lacking. In this article, we describe case patient who developed after vagotomy later received infusion donor feces microbiota, report our findings. Methods A 44-year-old woman septic...
Intestinal ischemia-reperfusion (I/R) plays an important role in critical illnesses. Gut flora participate the pathogenesis of injury. This study is aimed at unraveling colonic microbiota alteration pattern and identifying specific bacterial species that differ significantly as well observing epithelium change same injury model during reperfusion time course.Denaturing gradient gel electrophoresis (DGGE) was used to monitor control rats experimental underwent 0.5 hour ischemia 1, 3, 6, 12,...
Infectious complications are a leading cause of death for patients with severe acute pancreatitis (SAP). Yet, our knowledge about details the blood microbial landscape in SAP remains limited. Recently, some studies have reported that peripheral circulation harbors diverse bacterial community healthy and septic subjects. The objective this study was to examine presence microbiome its potential role development infectious complications. Here we conducted prospective observational on cohort 50...
Objectives: To define the characteristic of bacteremia in patients with acute pancreatitis and determine its possible association disease severity. Design: A prospective controlled study. Setting: ICU Jinling Hospital, China. Patients: total 48 mild or severe were enrolled Interventions: None. Measurements Main Results: Samples peripheral blood collected from at 4 5 9 10 days after was definitely diagnosed. Resulting DNA analyzed using denaturing gradient gel electrophoresis, separated...
Abstract Background Inflammatory bowel disease (IBD) involves a breakdown in interactions between the host immune response and resident commensal microbiota. Recent studies have suggested gut physiology pathology relevant to human IBD can be rapidly modeled zebrafish larvae. The aim of this study was investigate dysbiosis intestinal microbiota models with IBD-like enterocolitis using culture-independent techniques. Results induced by exposing larval trinitrobenzenesulfonic acid (TNBS)....
Background: Management of patients with non-obstructive coronary artery disease (CAD) identified by CT angiography (CCTA) remains challenging due to the lacks clear guidelines. Traditional anatomical evaluation techniques might not reliably pinpoint those at an increased risk for cardiovascular events, creating a critical gap in patient care. Although derived fractional flow reserve (CT-FFR) provides non-invasive functional assessment and is increasingly recognized as crucial tool deciding...
Abstract Multiple myeloma (MM) is a prevalent hematologic malignancy characterized by abnormal proliferation of cloned plasma cells. Given the aggressive nature and drug resistance MM cells, identification novel genes could provide valuable insights for treatment. In this study we performed machine learning in RNA microarray data purified cell samples from five independent cohorts with 957 patients, identified O-GlcNAcylation transferase ( OGT ) division cycle 27 CDC27 as key prognostic MM....
The dysbiosis of intestinal microbiota has been established in Crohn's disease (CD), but the molecular characterization this Chinese subjects with CD remains unclear. This study aims to investigate predominant bacterial composition faecal and mucosal-associated patients using culture-independent techniques.Eighteen 9 healthy controls were included study. faeces mucosal tissues from ulcerated nonulcerated sites subjected community fingerprinting denaturing gradient gel electrophoresis (DGGE)....
Recent studies have demonstrated the presence of a circulating microbiome in blood healthy subjects and chronic inflammatory patients. However, our knowledge regarding its potential roles surgical patients remains very limited. The objective this study was to determine microbial landscape explore associations with postoperative sepsis. 2825 who underwent treatments were screened for enrollment 204 cases recruited study. sub-grouped into noninfected, infected, sepsis, septic shock according...
A mounting body of evidences suggests that patients with chronic heart failure (HF) frequently experience cognitive impairments, but the neuroanatomical mechanism underlying these impairments remains elusive. In this retrospective study, 49 HF and healthy controls (HCs) underwent brain structural MRI scans assessments. Cortical morphology index (cortical thickness, complexity, sulcal depth gyrification) were evaluated. Correlations between cortical scores clinical variables explored....
It has been known that the gut microbiota plays a central role in shaping normal mucosal immunity, however, little information is available whether variability of lymphocytes impacts commensal flora. Here, we applied cynomolgus monkey model to characterize structure and composition response lymphocyte depletion determine their potential association. Molecular profiling 16S rDNA showed intestinal was perturbed after were recovered following repopulation. Some specific bacteria from orders...