A5107115582- Radiomics and Machine Learning in Medical Imaging
- Thyroid Cancer Diagnosis and Treatment
- MRI in cancer diagnosis
- Kidney Stones and Urolithiasis Treatments
- Colorectal Cancer Screening and Detection
- Microbial Inactivation Methods
- Tuberculosis Research and Epidemiology
- Toxin Mechanisms and Immunotoxins
- Hepatocellular Carcinoma Treatment and Prognosis
- Pneumocystis jirovecii pneumonia detection and treatment
- Multiple and Secondary Primary Cancers
- Metastasis and carcinoma case studies
- Mycobacterium research and diagnosis
- Medical Imaging and Pathology Studies
- Pelvic and Acetabular Injuries
- Plant tissue culture and regeneration
- Multiple Myeloma Research and Treatments
- Genetic factors in colorectal cancer
- Breast Lesions and Carcinomas
- Ginseng Biological Effects and Applications
- Gastric Cancer Management and Outcomes
- Infectious Diseases and Tuberculosis
- Pediatric Urology and Nephrology Studies
- Ubiquitin and proteasome pathways
- Radiation Effects and Dosimetry
Huazhong University of Science and Technology
2018-2025
University of Hong Kong
2025
Hong Kong Science and Technology Parks Corporation
2025
Tongji Hospital
2018-2025
Lanzhou University Second Hospital
2021-2024
Lanzhou University
2021-2024
Jinyintan Hospital
2022-2023
Wuhan Institute of Virology
2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2023
Academy of Medical Sciences
2023
Abstract Background Accurate diagnosis of unexplained cervical lymphadenopathy (CLA) using medical images heavily relies on the experience radiologists, which is even worse for CLA patients in underdeveloped countries and regions, because lack expertise reliable history. This study aimed to develop a deep learning (DL) radiomics model based B-mode color Doppler ultrasound assisting radiologists improve their diagnoses etiology CLA. Methods Patients with who received examinations from three...
Abstract Multiple myeloma (MM) is a prevalent hematologic malignancy characterized by abnormal proliferation of cloned plasma cells. Given the aggressive nature and drug resistance MM cells, identification novel genes could provide valuable insights for treatment. In this study we performed machine learning in RNA microarray data purified cell samples from five independent cohorts with 957 patients, identified O-GlcNAcylation transferase ( OGT ) division cycle 27 CDC27 as key prognostic MM....
Prostate cancer is a prevalent condition among older males, with radical prostatectomy being the standard treatment. However, this procedure can inevitably impact urinary and sexual functions. Irreversible electroporation represents an innovative therapeutic approach that employs high-voltage electrical pulses to selectively eradicate tumor cells, potentially preserving vital normal tissue. This follow-up study included 11 prostate patients who underwent IRE therapy from November 2021...
Objectives Time‐intensity curves (TICs) of contrast‐enhanced ultrasound (CEUS) were analyzed retrospectively to differentiate between low‐grade and high‐grade bladder urothelial carcinoma, investigate correlation with tumor microvessel density (MVD). Methods The data 105 patients pathologically confirmed carcinoma (55 50 high‐grade) reviewed. Lesions examined before surgery using conventional CEUS TIC analysis. parameters time from peak one‐half the signal intensity (TPH) corresponding...
To explore the correlation between two-dimensional ultrasound (2D-US), contrast-enhanced (CEUS) and microvascular invasion (MVI) in hepatocellular carcinoma (HCC).In this retrospective study, 56 patients with surgically pathologically confirmed HCC lesions were included. Patients classified according to presence of MVI: MVI positive group (n = 17) negative 39). 2D-US CEUS examinations performed within two weeks before surgery. The features analyzed for MVI. Statistically significant...
Objective To investigate if the addition of bedaquiline and clofazimine to a treatment regimen for multidrug-resistant tuberculosis (MDR-TB) could improve patient outcomes. Methods A prospective, randomized, controlled study was conducted in patients with MDR-TB. Treatment 18 months. Patients experimental group received their regular whereas control did not. Results 68 MDR-TB were randomised treatment, 34 each group. At end cure rates statistically significantly greater compared (82% vs....
To investigate the effect of licochalcone A (LCA) on proliferation and cell cycle human lung squamous carcinoma cells explore its possible molecular mechanism.MTT assay was used to detect changes in H226 after treatment with different concentrations LCA for 48 h, IC50 calculated. Flow cytometry analyze treated 10, 20, 40 μmol/L LCA, expressions cyclin D1, cyclin-dependent kinase CDK2 CDK4, p-PI3K, PI3K, p-Akt, Akt were detected using Western blotting. The intraperitoneal injection 24 days...
To assess the diagnostic value of echogenic foci in papillary thyroid carcinoma (PTC) and relationship between aggressiveness PTC.From January 2018 to 2021, a total 950 patients diagnosed with nodules (n = 1113) our hospital were retrospectively analyzed. Among 1113 nodules, single PTC 527 confirmed by surgery was studied for their aggressive biological behavior. The patterns classified as: no foci, sparse punctate focal diffuse petal-like comet-tail artifacts, coarse peripheral rim...
Previously, some studies have proposed that total laparoscopic gastrectomy (TLG) is superior to laparoscopic-assisted (LAG) in terms of safety and feasibility based on the related intraoperative operative parameters incidence postoperative complications. However, there are still few changes liver function patients undergoing LG. The present study compared with TLG LAG, aiming explore whether a difference influence LAG patients.To investigate patients.The collected 80 who underwent LG from...
Background. To evaluate the clinical characteristics and angiographic features of transcatheter embolization (TAE) in patients with active bleeding after percutaneous nephrolithotomy (PCNL). Methods. Between 2009 2018, 45 who underwent TAE for hemorrhage control PCNL were reviewed retrospectively. Patient analyzed. Results. Of 3148 patients, (1.4%) treated PCNL. The interval from episode to was 3 days (1,6). Arterial laceration, arteriovenous fistula, negative finding found 28 (62.2%), 7...
Sentinel lymph node biopsy (SLNB), as a common method for axillary staging of early breast cancer, has gradually attracted people's attention to the false-negative rate and postoperative complications. The aim study is investigate clinical value preoperative contrast-enhanced ultrasound (CEUS) intraoperative SLNB in cancer patients.A total 201 patients scheduled from September 2018 April 2021 were collected consecutively. Preoperative CEUS was used identify sentinel nodes (SLN) lymphatic...
Correction to: Deep learning radiomics of multimodal ultrasound for classifying metastatic cervical lymphadenopathy into primary cancer sites: a feasibility studyUltraschall Med eFirstDOI: 10.1055/a-2161-9369
<title>Abstract</title> Background Prostate cancer is a prevalent condition among elderly males, with radical prostatectomy being the standard treatment. However, this procedure can inevitably impact urinary and sexual functions. Irreversible electroporation represents an innovative therapeutic approach that employs high-voltage electrical pulses to selectively eradicate tumor cells, potentially preserving vital normal tissue. Materials methods This follow-up study included 11 prostate...
Abstract Purpose To investigate the feasibility of deep learning radiomics (DLR) based on multimodal ultrasound to differentiate primary cancer sites metastatic cervical lymphadenopathy (CLA). Materials and Methods This study analyzed 280 biopsy-confirmed CLAs from patients, including 54 head neck squamous cell carcinoma (HNSCC), 58 thyroid (TC), 92 lung (LC), 76 gastrointestinal (GIC). Before biopsy, patients underwent conventional (CUS), elastography (UE), contrast-enhanced (CEUS). Based...
Abstract Aim: This study was conducted to determine the impact of patient-centered care (PCC) on treatment adherence and outcome patientswith multidrug- or rifampicin-resistant tuberculosis (MDR/RR-TB). Background: Treatment is critical successful outcomes MDR/RR-TB. However, very few studies published had addressed how improve it. Me thods: retrospectivelyanalyzed MDR/RR-TB patient with two different kinds care: clinical for group A PCC B. Results: There were 128 patients assigned in 155...
Objective: To analyze the features of degenerating cystic thyroid nodules (DCTN) on conventional ultrasound and contrast-enhanced (CEUS), to explore differentiation between DCTN papillary carcinomas (PTC). Methods: A total 46 (39 cases, including 12 males 27 females, with an age range 25 76 years) 36 PTC (32 8 24 23 68 diagnosed via fine- needle aspiration (FNA) or surgery from February 2019 January 2020 in First Affiliated Hospital Nanchang University were enrolled. The size, shape, margin,...