A5060990989- Cardiovascular Function and Risk Factors
- Congenital heart defects research
- Tissue Engineering and Regenerative Medicine
- Congenital Heart Disease Studies
- Cardiac Imaging and Diagnostics
- Renal and related cancers
- Renal cell carcinoma treatment
- Infective Endocarditis Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Coronary Artery Anomalies
- Thyroid Cancer Diagnosis and Treatment
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Liver Disease Diagnosis and Treatment
- Pediatric Urology and Nephrology Studies
- Hepatitis Viruses Studies and Epidemiology
- Cardiovascular Health and Disease Prevention
- Radiation Dose and Imaging
- RNA modifications and cancer
- MicroRNA in disease regulation
- Mechanical Circulatory Support Devices
- Liver Disease and Transplantation
- Thyroid and Parathyroid Surgery
- Genetics and Neurodevelopmental Disorders
- Streptococcal Infections and Treatments
First Affiliated Hospital of Nanchang University
2017-2024
Nanchang University
2017-2024
First Affiliated Hospital of Jiangxi Medical College
2024
Albert Einstein College of Medicine
2022
Jiangxi University of Traditional Chinese Medicine
2022
The presence of gross extrathyroidal extension (ETE) in thyroid cancer will affect the prognosis patients, but imaging examination cannot provide a reliable diagnosis for it. This study was conducted to develop deep learning (DL) model localization and evaluation nodules ultrasound images before surgery ETE.From January 2016 December 2021 grayscale 806 (4451 images) from 4 medical centers were retrospectively analyzed, including 517 no ETE 289 nodules. 283 158 randomly selected internal...
Despite the importance of cardiomyocyte proliferation in cardiac development and regeneration, mechanisms that promote cell cycle remain incompletely understood. RE1 silencing transcription factor (REST) is a transcriptional repressor neuronal genes. Here we show REST also regulates cycle. binds represses inhibitor gene p21 required for mouse regeneration. Rest deletion de-represses inhibits embryonic or regenerating hearts. By contrast, overexpression cultured cardiomyocytes increases...
To investigate the diagnostic value of multimodal ultrasound imaging composed conventional ultrasonography (US), contrast-enhanced (CEUS), and shear wave elastography (SWE) for liver tumors.Between October 2017 2019, US, CEUS, SWE examinations a total 158 tumors in 136 patients at The First Affiliated Hospital Nanchang University were performed. histopathological or results used as controls to evaluate sensitivity, specificity, accuracy, positive predictive value, negative SWE, imaging,...
Abstract The aim of this study was to evaluate the application transthoracic echocardiography for diagnosis infective endocarditis (IE) provide a basis better treatment IE. From October 2016 2018, 87 consecutive patients with IE at our hospital were selected study. All subjected echocardiography. morphology, structure, activity, and closure patients’ heart valves observed vegetation identification, size, number, location, echo intensity vegetation, as well degree valve involvement,...
Background: Mitral valve cleft (MVC) is the most common cause of congenital mitral insufficiency, and MVC may occur alone or in association with other heart lesions. Direct suture valvuloplasty are major effective treatments for regurgitation (MR) caused by MVC. Therefore, it important to determine location magnitude pathological damage due when selecting a surgical procedure treatment. This study explored application value transthoracic real-time 3-dimensional (3D) echocardiography (RT-3DE)...
Abstract Developmental etiologies causing complex congenital aortic root abnormalities are unknown. Here we show that deletion of Sox17 in endothelium mice causes underdeveloped leading to a bicuspid valve due the absence non-coronary leaflet and mispositioned left coronary ostium. The respective defects associated with reduced proliferation mesenchyme smooth muscle derived from second heart field cardiomyocytes. Mechanistically, SOX17 occupies Pdgfb transcriptional enhancer promote its...
Patients with diffuse large B-cell lymphoma (DLBCL) often experience a poor prognosis due to cardiac damage induced by anthracycline chemotherapy, left ventricular diastolic dysfunction manifesting early. Vector Flow Mapping (VFM) is novel technology, and its effectiveness in detecting following chemotherapy remains unverified.
Abstract Ultrasound elastography has become a promising noninvasive approach for assessing liver fibrosis. The purpose of this study was to evaluate the diagnosis ability stiffness detected by shear wave (SWE) predicting presence esophageal varices (EVs) in cirrhotic patients. Four hundred sixty-eight patients were enrolled consecutively. Liver and EVs SWE endoscopy, respectively. baseline characteristics recorded, areas under receiver operating characteristic curves (AUROCs) used compare...
The aim of this research is to investigate the application value TTE in diagnosis anomalous origin left coronary artery from pulmonary (ALCAPA).The echocardiographic findings 11 patients with ALCAPA confirmed by surgery our hospital October 2007 December 2018 were retrospectively analyzed and compared preoperative computed tomography angiography (CTA) intraoperative diagnosis.Surgery was performed all establish dual system. Four underwent Takeuchi procedure 7 had re-implantation artery. CTA...
Purpose To investigate the diagnostic value of nonintrusive left ventricular pressure–strain loop (LV-PSL) for assessing overall myocardial function in sufferers with non-ST-segment elevation acute coronary syndrome (NSTE-ACS) or without stenosis. The results this research might provide insights into diagnosis and management NSTE-ACS. Methods All 268 NSTE-ACS who were received by First Affiliated Hospital Nanchang University between June 2019 2021 enrolled. Sufferers single multiple...
Abstract Objective The noninvasive right ventricular pressure‐strain loop (PSL) represents a novel method for the quantitative assessment of myocardial function. Given that atrial septal defect (ASD) is prevalent congenital heart anomaly associated with volume overload, this study aimed to quantitatively assess function ventricle in ASD patients pre‐ and post‐occlusion by PSL. Methods This included 36 diagnosed secundum group 30 healthy adults (control group). We compared conventional...
Background:: Type 2 diabetes mellitus (T2DM) and hypertension (HT) are the two most common underlying diseases worldwide, they often coexist. The long-term existence of both may lead to left ventricular dysfunction. Therefore, evaluating cardiac function T2DM patients with HT is vital guide treatment improve prognosis. Left pressure strain loops (LVPSL) combine afterload, which can quantify energy expenditure detect subclinical systolic Many studies have focused on myocardial work (MW) in...
Lymphaticovenous anastomosis (LVA) surgery is an effective treatment for lymphedema. Accurate evaluation and localization of the superficial lymphatic vessels before operation crucial success operation. Contrast-enhanced ultrasound (CEUS) a new technology, its clinical application value in LVA has not been established.This study aimed to assess efficacy CEUS provide novel approach assessment vessels.Retrospective analysis imaging surgical data was performed on 20 patients. Among them, 10...
The Bosniak classification system based on contrast-enhanced computed tomography (CECT) is commonly used for the differential diagnosis of cystic renal masses. Contrastenhanced ultrasound (CEUS) a relatively novel technique, which has gradually played an important role in cell carcinoma (CRCC) due to its safety and lowest price.The aim study investigate application value CEUS into masses.32 masses from January 2018 December 2019 were selected. images conventional (US), CECT subjects...
Cystic Renal Cell Carcinoma (CRCC) is often difficult to differentiate from complex cysts with sonographic manifestations of renal carcinoma. Contrast-Enhanced Ultrasound (CEUS) a new technology, and its clinical utility in the diagnosis cystic mass has not been established.The objective this study analyze characteristics CEUS masses explore significance value CRCC.This was retrospective study. A total 32 January 2018 December 2019 were selected. The images conventional (US) confirmed via...
Abstract Purpose: To evaluate the myocardial work (MW) changes in type 2 diabetes mellitus (T2DM) patients with or without hypertension(HT) using left ventricular pressure strain loops（LVPSL）, and to find independent related factors of MW parameters. Methods: 40 T2DM patients, 38 HT 35 controls were enrolled. The differences between clinical data, conventional ultrasound parameters analyzed among three groups. Results: global longitudinal (GLS) group T2DM+HT was lower than ( P ＜0.05). index...
Objective: To analyze the features of degenerating cystic thyroid nodules (DCTN) on conventional ultrasound and contrast-enhanced (CEUS), to explore differentiation between DCTN papillary carcinomas (PTC). Methods: A total 46 (39 cases, including 12 males 27 females, with an age range 25 76 years) 36 PTC (32 8 24 23 68 diagnosed via fine- needle aspiration (FNA) or surgery from February 2019 January 2020 in First Affiliated Hospital Nanchang University were enrolled. The size, shape, margin,...
Abstract Purposes: The purposes of this study were to use noninvasive Left ventricular pressure-strain loops (LV-PSLs) compare the various myocardial work indices in patients with hypertrophic cardiomyopathy (NHCM) and evaluate clinical application evaluation NHCM patients.Method: 80 45 healthy subjects enrolled. All selectors underwent Echocardiography examination. Dynamic images standard apical three-chamber, four-chamber, two-chamber view collected, left ventricle measured by LV-PSLs....