A5024757777- Ocular Infections and Treatments
- Corneal surgery and disorders
- Ocular Surface and Contact Lens
- Legionella and Acanthamoeba research
- Corneal Surgery and Treatments
- Intraocular Surgery and Lenses
- Glaucoma and retinal disorders
- Ocular Diseases and Behçet’s Syndrome
- Herpesvirus Infections and Treatments
- Ophthalmology and Visual Impairment Studies
- Connexins and lens biology
- Retinal and Optic Conditions
- Yersinia bacterium, plague, ectoparasites research
- Traumatic Ocular and Foreign Body Injuries
- Retinal Imaging and Analysis
- Cytomegalovirus and herpesvirus research
- Bacterial biofilms and quorum sensing
- Antifungal resistance and susceptibility
- Bacterial Identification and Susceptibility Testing
- Ocular Disorders and Treatments
- Medical and Biological Ozone Research
- Retinal and Macular Surgery
- Heme Oxygenase-1 and Carbon Monoxide
- Virus-based gene therapy research
- Acne and Rosacea Treatments and Effects
University of Illinois Chicago
2016-2025
New York Eye and Ear Infirmary
2009-2025
Cleveland Clinic
2025
Hôpital Raymond-Poincaré
2023
Illinois College
2015-2023
University of Illinois Urbana-Champaign
2007-2020
Prevent Blindness
2015-2020
Visual Sciences (United States)
2017
University of Minnesota
2016
Research to Prevent Blindness
2015
ABSTRACT PURPOSE: Wavefront analysis has demonstrated that refractive surgery-induced corneal first surface aberrations are large, dominated by symmetric (spherical-like aberrations), and correlated to measures of visual performance. It is not clear whether the correlation between performance can be generalized other conditions where large asymmetric (coma-like aberrations) may dominate aberration structure. The purpose research reported here was determine general utility wavefront in...
Purpose: To investigate the incidence of fungal infections after corneal transplantation to determine whether storage media supplementation with an antifungal should be considered. Methods: Adverse reactions reported Eye Bank Association America through online adverse reaction reporting system between January 1, 2007, and December 31, 2010, were reviewed identify cases recipient infection. Data collected regarding donor, donor cornea, recovery processing, mate culture clinical course...
Author(s): Ung, Lawson; Acharya, Nisha R; Agarwal, Tushar; Alfonso, Eduardo C; Bagga, Bhupesh; Bispo, Paulo Jm; Burton, Matthew J; Dart, John Kg; Doan, Thuy; Fleiszig, Suzanne Mj; Garg, Prashant; Gilmore, Michael S; Gritz, David Hazlett, Linda D; Iovieno, Alfonso; Jhanji, Vishal; Kempen, H; Lee, Cecilia Lietman, Thomas M; Margolis, Todd P; McLeod, Stephen Mehta, Jod Miller, Darlene; Pearlman, Eric; Prajna, Lalitha; N Venkatesh; Seitzman, Gerami Shanbhag, Swapna Sharma, Namrata; Savitri;...
Purpose: To compare the relative diagnostic value of confocal microscopy and superficial corneal cultures in diagnosis Acanthamoeba keratitis by using clinical microbiologic definitions disease. Methods: Results microscopy, smear, culture were analyzed for validity against 2 different a composite standard keratitis. Results: In patients with both characteristics objective evidence keratitis, exhibited sensitivity 90.6% (95% confidence interval [CI]: 79.3%-96.9%) specificity 100% CI:...
<h3>Objective</h3> To determine whether preoperative and/or postoperative central endothelial cell density (ECD) and its rate of decline postoperatively are predictive graft failure caused by decompensation following penetrating keratoplasty to treat a moderate-risk condition, principally, Fuchs dystrophy or pseudophakic corneal edema. <h3>Methods</h3> In subset Cornea Donor Study participants, reading center determined ECD from available specular images for 17 grafts that failed because 483...
Purpose: To describe the trend of Acanthamoeba keratitis case reports following an outbreak and recall a multipurpose contact lens disinfection solution. is serious eye infection caused by free-living amoeba that primarily affects users.Methods: A convenience sample 13 ophthalmology centers laboratories in USA, provided annual numbers cases diagnosed between 1999–2009 monthly 2007–2009. Data on ophthalmic preparations anti-Acanthamoeba therapies were collected from national compounding...
To develop an artificial intelligence (AI) model to diagnose Acanthamoeba keratitis (AK) based on in vivo confocal microscopy (IVCM) images extracted from the Heidelberg Retinal Tomograph 3 (HRT 3).
To study the outcomes of AlphaCor implantation.: The artificial cornea is indicated for corneal blindness not treatable by donor grafting. Prospective preoperative and follow-up data were collected. Data evaluated using SPSS statistical analysis outcomes, trends, associations.This report includes returned through February 28, 2006, all 322 devices implanted, with mean in situ 15.5 months a maximum 7.4 years. probability retention at 6 1 2 years protocol cases was 92%, 80%, 62%, respectively,...
The purpose of this study was to describe the clinical presentation 3 cases Alternaria keratitis and their response medical therapy.All diagnosed treated at University Illinois Eye Ear Infirmary from 1999 2007 were reviewed for presentation, antifungal therapy, final visual acuity.Three identified. All patients presented with an indolent steroid-treated a history recent cataract surgery, agricultural trauma, or contact lens wear. None responded natamycin, 1 also failed respond topical...
<h3>Importance</h3> Demonstrating that success of Descemet stripping automated endothelial keratoplasty is similar across donor cornea preservation times (PTs) could increase the pool. <h3>Objective</h3> To determine whether 3-year rate graft using corneal tissue preserved 8 to 14 days noninferior 7 or less. <h3>Design, Setting, and Participants</h3> A multicenter, double-masked, randomized noninferiority clinical trial was conducted from April 16, 2012, June 5, 2017, at 40 sites (70...
The aim of this study was to report the successful medical management 2 cases late-onset endothelial keratoplasty-related stromal interface infections.All infections treated with intrastromal antifungal injections were compiled. following information collected: demographic data, surgical indications, donor rim cultures, mate outcomes, clinical course, diagnostic tests, and outcome.Two fungal keratitis diagnosed on appearance confocal microscopy identified. Both patients refused undergo...
Fungal contamination and infection from donor tissues processed for endothelial keratoplasty is a growing concern, prompting analysis of after processing.To determine whether eyebank-processed tissue at higher risk than unprocessed to model eyebank processing with regard room temperature exposure on Candida growth in optisol-gentamicin streptomycin (GS) without antifungal supplementation.An examination the 2013 Eversight Eyebank Study follow-up database factors associated post-keratoplasty...
Background: Management of patients with non-obstructive coronary artery disease (CAD) identified by CT angiography (CCTA) remains challenging due to the lacks clear guidelines. Traditional anatomical evaluation techniques might not reliably pinpoint those at an increased risk for cardiovascular events, creating a critical gap in patient care. Although derived fractional flow reserve (CT-FFR) provides non-invasive functional assessment and is increasingly recognized as crucial tool deciding...
To report the indications, postoperative visual outcomes, and long-term graft survival of primary pediatric keratoplasties performed at a single tertiary care center. We conducted retrospective review patients (16 years younger) who underwent surgical intervention for corneal opacity center to evaluate rehabilitation. Seventy-three eyes 46 met inclusion criteria. The mean patient age time transplantation was 7.44 (range, 5 months-15.72 years), average follow-up 5.82 years. Forty (56%) had...
The Cornea Donor Study (CDS) is an ongoing study that being conducted to determine whether donor age related long-term corneal graft survival. Characteristics of the population have been evaluated with respect age, endothelial cell density, and death preservation interval.Within context a prospective, double-masked, controlled trial, 1101 corneas were assigned without regard age.Slit-lamp characteristics showed little variation except for presence arcus. As time decreased, fewer epithelial...