A5087622149- Corneal surgery and disorders
- Corneal Surgery and Treatments
- Intraocular Surgery and Lenses
- Glaucoma and retinal disorders
- Ocular Surface and Contact Lens
- Ocular Infections and Treatments
- Ophthalmology and Visual Impairment Studies
- Ocular Diseases and Behçet’s Syndrome
- Retinal and Macular Surgery
- Connective tissue disorders research
- Retinal and Optic Conditions
- Autoimmune Bullous Skin Diseases
- Urticaria and Related Conditions
- Herpesvirus Infections and Treatments
- Traumatic Ocular and Foreign Body Injuries
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Ocular Disorders and Treatments
- Sympathectomy and Hyperhidrosis Treatments
- Ocular Oncology and Treatments
- Healthcare and Venom Research
- Cancer and Skin Lesions
- Lysosomal Storage Disorders Research
- Cytomegalovirus and herpesvirus research
- Plant Pathogens and Fungal Diseases
- Methemoglobinemia and Tumor Lysis Syndrome
Wills Eye Hospital
2011-2025
Thomas Jefferson University
2003-2023
Philadelphia University
1982-2019
University of Illinois Chicago
2002-2016
SUNY Upstate Medical University
2016
University of Illinois Urbana-Champaign
2016
Allergan (United States)
2015
Association for Research in Vision and Ophthalmology
2012
Penn Presbyterian Medical Center
1984-2011
University of Toronto
2010
<h3>Background/aims</h3> To report the short-term safety profile and clinical outcomes of scleral fixation intraocular lenses (IOLs) using Gore-Tex suture. <h3>Methods</h3> Retrospective, interventional case series. 85 eyes 84 patients undergoing ab externo a Bausch Lomb Akreos AO60 or Alcon CZ70BD IOL Primary outcome measures were change in visual acuity occurrence intraoperative postoperative complications with minimum follow-up 90 days. <h3>Results</h3> identified. Mean logarithm angle...
Purpose. To identify current indications and trends in for penetrating keratoplasty associated procedures. Methods. Retrospective chart review of all patients who underwent at Wills Eye Hospital from January 1, 1996 to December 31, 2000. Results. A total 1,529 corneal transplants were performed during this 5-year period. The leading pseudophakic bullous keratopathy (PBK) 416 (27.2%) cases, followed by regraft 276 (18.1%), keratoconus 236 (15.4%), Fuchs endothelial dystrophy 233 (15.2%)...
<h3>Objective</h3> To determine whether preoperative and/or postoperative central endothelial cell density (ECD) and its rate of decline postoperatively are predictive graft failure caused by decompensation following penetrating keratoplasty to treat a moderate-risk condition, principally, Fuchs dystrophy or pseudophakic corneal edema. <h3>Methods</h3> In subset Cornea Donor Study participants, reading center determined ECD from available specular images for 17 grafts that failed because 483...
To evaluate the indications and outcomes of sutureless amniotic membrane transplant (AMT; ProKera) in management ocular surface disorders.Chart review patients who had ProKera (Bio-Tissue, Inc.) implantation for disorders between June 2008 May 2012 at 3 ophthalmology practices Philadelphia, PA. The parameters evaluated included age, sex, indication AMT, any other combined procedure, duration retention membrane, effect on healing, follow-up time, complications.There were 35 eyes 33 with a...
To identify current indications and trends in for penetrating keratoplasty (PKP) associated procedures.Retrospective chart review of all patients who underwent PKP at Wills Eye Institute from January 1, 2001, to December 31, 2005.A total 1,162 cases were performed this 5-year period. Leading pseudophakic corneal edema (PCE) 330 (28.4%) cases, followed by regraft 250 (22.0%), keratoconus 186 (16%), Fuchs' endothelial dystrophy 126 (10.8%) cases. Of the PCE, 232 (70.3%) with posterior chamber...
Purpose: To report the clinical, pathologic, and genetic findings in a family with early-onset pterygia, corneal vascularization, myofibromatous lesions. Methods: We performed analysis of 12 members originating Puebla Mexico, who manifested pterygia/pseudopterygia opacification transmitted an autosomal-dominant inheritance pattern. Three unaffected also were evaluated. Results: Clinical included isolated subepithelial anterior stromal opacities associated varying degree combination pterygia...
To identify changing trends in indications for penetrating keratoplasty and associated surgical procedures.Review of charts from all patients who underwent at Wills Eye Hospital January 1, 1989 through December 31, 1995.A total 2,442 corneal transplants were performed 2,186 patients. The leading indication was pseudophakic edema, accounting 634 cases (26.0%); 54.7% them with anterior chamber intraocular lenses, 36.4% posterior 3.1% iris-fixated lenses. Regraft (17.8%), Fuchs' dystrophy...
The association of glaucoma and penetrating keratoplasty presents a difficult management problem, particularly when medical therapy conventional surgery have failed. We found alloplastic tube shunt to be an effective method for intraocular pressure control in glaucomatous eyes subjected keratoplasty. report 46 patients who underwent implantation before (13 patients, group A), combination with (17 B), or after (16 C) All groups had significantly lowered postoperatively. most common...
• Twelve cases of traumatic wound dehiscence occurred in ten patients after penetrating keratoplasty. Nine the were males between ages 11 and 44 years. Ten 12 ruptures with sutures place. Final visual acuity was better than 6/60 only four patients. The grafts have remained clear six patients, while one patient awaits a regraft. Four required repeat primary cause failure damage to retina posterior segment. importance protecting eye corneal transplantation is stressed.
<h3>Importance</h3> The identification of steep corneal curvatures in a significant percentage patients with posterior polymorphous dystrophy (PPCD) confirms this previously reported association and suggests role for the ZEB1 protein keratocyte function. <h3>Objective</h3> To determine whether PPCD is characterized by steepening. <h3>Design, Setting, Participants</h3> Cross-sectional study at university-based private ophthalmology practices 38 individuals (27 affected 11 unaffected) from 23...
To evaluate the clinical outcomes of mycophenolate mofetil (MMF) treatment mucous membrane pemphigoid (MMP).This is a retrospective analysis consecutive patients with MMP seen in Ocular Surface Disease Clinic at Wills Eye Institute, between January 1, 2004, and December 31, 2010, treated MMF. The main measured were control inflammation discontinuation MMF.A total 23 taking MMF identified. median age MMF-treated was 77.0 years. Eleven (47.8%) had biopsy-proven MMP. All least Foster grading...
• Band keratopathy developed rapidly in two patients following uneventful phacoemulsification and intraocular lens implantation using BSS Plus (balanced salt solution enriched with glutathione, bicarbonate, glucose) infusion Viscoat (chondroitin sulfate-sodium hyaluronate), which was left the anterior chamber at conclusion of procedure. Histopathologic evaluation corneal tissue obtained from one patient time edetic acid chelation revealed histochemical findings consistent stromal...
Purpose. To describe the treatment of Schnyder's crystalline dystrophy (SCD) with excimer laser phototherapeutic keratectomy (PTK). Methods. Chart review three patients (four eyes) SCD treated PTK between March 1992 and December 1998. Pre-and posttreatment visual acuity, subjective glare, photophobia, manifest refraction, ultrasound pachymetry, hyperopic shift, biomicroscopic findings were studied. Brightness acuity testing (BAT) was evaluated in two eyes. Results. Four eyes during study...
We report a case of Ferrara intracorneal ring (Mediphacos) implantation and cataract surgery for the correction pellucid marginal corneal degeneration. Preoperatively, patient's uncorrected visual acuity (UCVA) was 0.05 in right eye 0.10 left eye. The best spectacle-corrected (BSCVA) 0.50 with −2.00 −11.25 × 80 0.60 −5.50 95 One month postoperatively, UCVA 0.30 BSCVA 0.80 −1.00 −0.75 −1.25 160 intrastromal rings resulted more regular shape reduction astigmatism good recovery.
Purpose: To report a case series of eyes with posterior polymorphous corneal dystrophy and steep nonkeratoconic corneas. Methods: Retrospective, descriptive, nonrandomized series. Results: Thirty-five 18 patients (14 cases from 6 families 4 isolated cases) diffuse had mean topographic simulated keratometry readings 52.21 diopters (D), range 46.47 D to 59.86 an SD 3.69 D, no slit-lamp or findings suggestive keratoconus. Conclusions: The in this demonstrate
Purpose: To determine whether central discoid corneal dystrophy (CDCD), previously reported as a novel dystrophy, is actually Schnyder (SCD) through screening of the UBIAD1 gene in members family which CDCD was reported. Methods: Genetic analysis performed 3 affected and 1 unaffected member pedigree with including 31-year-old proband. Results: All 4 described demonstrated clouding, subtle, superficial, crystalline deposits noted one individuals. Screening individuals unreported missense...