A5106544929- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Corneal surgery and disorders
- Retinal Imaging and Analysis
- Retinal and Optic Conditions
- Ophthalmology and Visual Impairment Studies
- Ocular Diseases and Behçet’s Syndrome
- Corneal Surgery and Treatments
- Ocular Surface and Contact Lens
- Intraocular Surgery and Lenses
- Toxoplasma gondii Research Studies
- Musculoskeletal pain and rehabilitation
- Ophthalmology and Eye Disorders
- Visual perception and processing mechanisms
- Ocular Infections and Treatments
- Retinal and Macular Surgery
- Cerebral Venous Sinus Thrombosis
- Retinal Development and Disorders
- HIV/AIDS Research and Interventions
- Cytomegalovirus and herpesvirus research
- Herpesvirus Infections and Treatments
- Air Quality and Health Impacts
- Optical Coherence Tomography Applications
- Ergonomics and Musculoskeletal Disorders
- Ocular Oncology and Treatments
Doheny Eye Institute
2015-2025
University of California, Los Angeles
2016-2025
Cornell University
2025
Chinese Academy of Sciences
2022-2024
University of Chinese Academy of Sciences
2024
Shanghai Institute of Optics and Fine Mechanics
2024
Fielding Graduate University
2014-2024
Zunyi Medical University
2024
Sun Yat-sen University
2023-2024
Wenzhou Medical University
2021-2023
The authors evaluated the effect of air pollution on occurrence birth defects ascertained by California Birth Defects Monitoring Program in neonates and fetuses delivered southern 1987–1993. By using measurements from ambient monitoring stations carbon monoxide (CO), nitrogen dioxide, ozone, particulate matter <10 μm aerodynamic diameter, they calculated average monthly exposure estimates for each pregnancy. Conventional, polytomous, hierarchical logistic regression was used to estimate odds...
Abstract Objective To examine associations between early developmental exposure to ambient pesticides and autism spectrum disorder. Design Population based case-control study. Setting California’s main agricultural region, Central Valley, using 1998-2010 birth data from the Office of Vital Statistics. 2961 individuals with a diagnosis disorder on Diagnostic Statistical Manual Mental Disorders , fourth edition, revised (up 31 December 2013), including 445 intellectual disability comorbidity,...
We evaluated the effect of air pollution exposure during pregnancy on occurrence preterm birth in a cohort 97,518 neonates born Southern California. used measurements carbon monoxide (CO), nitrogen dioxide, ozone, and particulate matter less than 10 μm (PM10) collected at 17 air-quality-monitoring stations to create average estimates for periods pregnancy. calculated crude adjusted risk ratios (RRs) premature by period-specific ambient levels. observed 20% increase per 50-μg PM10 levels...
We evaluated the effect of carbon monoxide (CO) exposures during last trimester pregnancy on frequency low birth weight among neonates born 1989-1993 to women living in Los Angeles, California, area. Using certificate data for that period, we assembled a retrospective cohort infants whose mothers resided within 2 miles 1 18 CO monitoring stations. Based gestational age and date each child, estimated last-trimester exposure by averaging corresponding 3 months daily concentrations registered...
Objectives. This study compared the relative effectiveness of cervical spine manipulation and mobilization for neck pain. Methods. Neck-pain patients were randomized to following conditions: with or without heat, electrical muscle stimulation, stimulation. Results. Of 960 eligible patients, 336 enrolled in study. Mean reductions pain disability similar groups through 6 months. Conclusions. Cervical yield comparable clinical outcomes.
To investigate the expression and role of Wnt signaling pathway in human limbal stem cells (LSCs).Total RNA was isolated from limbus central cornea. Limbal or cornea-specific transcripts were identified through quantitative real-time PCR. Protein molecules confirmed by immunohistochemistry on ocular tissue. Activation using lithium chloride achieved vitro its effects LSC differentiation proliferation evaluated.Expression Wnt2, Wnt6, Wnt11, Wnt16b, four inhibitors specific to region, whereas...
Purpose: To investigate the incidence of fungal infections after corneal transplantation to determine whether storage media supplementation with an antifungal should be considered. Methods: Adverse reactions reported Eye Bank Association America through online adverse reaction reporting system between January 1, 2007, and December 31, 2010, were reviewed identify cases recipient infection. Data collected regarding donor, donor cornea, recovery processing, mate culture clinical course...
Heart transplantation offers life-saving treatment for patients with end-stage heart failure; however, ischemia-reperfusion injury (IRI) and subsequent immune responses remain significant challenges. Current therapies primarily target adaptive immunity, limited options available addressing IRI innate activation. Although plant-derived vesicle-like nanoparticles show promise in managing diseases, their application organ complications is unexplored. Here, this work develops a novel reactive...
In Brief Purpose: To identify fluorescein angiography and optical coherence tomography (OCT) predictors for retinal pigment epithelial (RPE) tear in eyes with epithelium detachment (PED) associated neovascular age-related macular degeneration treated intravitreal vascular endothelial growth factor (VEGF) modulating therapy. Design: Retrospective comparative case series. Methods: a single institutional center, 60 consecutive patients PED VEGF therapy (either pegaptanib, bevacizumab, or...
To explore the association of angiographic nonperfusion with anterior segment and posterior neovascularization in central retinal vein occlusion (CRVO).An imaging database at one institution was searched for diagnosis occlusion. Ultra wide field fluorescein angiograms were graded image quality, presence neovascularization, quantity nonperfusion; an ischemic index (ISI) calculated. Charts reviewed to exclude eyes previous treatment determine which had or on day angiogram. Time from onset...
Purpose: To report the outcomes of Boston type I keratoprosthesis (Massachusetts Eye and Ear Infirmary, Boston, MA) in management corneal limbal stem cell deficiency (LSCD). Methods: A retrospective review all cases implantation performed by a single surgeon (A.J.A.) between May 1, 2004, March 31, 2010. Procedures for LSCD were identified, data collected regarding patients' ocular history, surgical procedure(s) performed, postoperative outcomes, including interval visual acuities, retention,...