A5025916991- Ocular Diseases and Behçet’s Syndrome
- Retinal and Optic Conditions
- Retinal Diseases and Treatments
- Systemic Lupus Erythematosus Research
- Cytomegalovirus and herpesvirus research
- CNS Lymphoma Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Ocular Infections and Treatments
- Herpesvirus Infections and Treatments
- Vasculitis and related conditions
- Toxoplasma gondii Research Studies
- Cerebral Venous Sinus Thrombosis
- Glaucoma and retinal disorders
- Sarcoidosis and Beryllium Toxicity Research
- Ocular Oncology and Treatments
- Chronic Lymphocytic Leukemia Research
- Viral-associated cancers and disorders
- Autoimmune and Inflammatory Disorders Research
- Infectious Diseases and Tuberculosis
- IgG4-Related and Inflammatory Diseases
- Autoimmune and Inflammatory Disorders
- Otitis Media and Relapsing Polychondritis
- Bartonella species infections research
- Hepatitis B Virus Studies
- Yersinia bacterium, plague, ectoparasites research
Assistance Publique – Hôpitaux de Paris
2006-2022
Sorbonne Université
2012-2021
Pitié-Salpêtrière Hospital
2012-2021
Hôpital d'instruction des Armées Percy
2021
Inserm
1999-2017
Centre National de la Recherche Scientifique
2008-2017
Centre National pour la Recherche Scientifique et Technique (CNRST)
2016
Centre d'Immunologie et des Maladies Infectieuses
2016
Université Paris Cité
1992-2015
Délégation Paris 6
1998-2014
Introduction There is a significant under-registration of blind and visually impaired patients attending ophthalmic departments. Blindness defined by the World Health Organization (WHO) as best possible corrected visual acuity in better eye less than 3/60 (20/400 or 0.05) corresponding field ≤10°. Severe impairment best-corrected more, but 6/60 (20/200 0.1) (40,49). In 1995, WHO estimated that nearly 38 million people world were 110 had severe impairment. 1997, total number was 44,800,000...
To evaluate the clinical, angiographic, and cytopathologic features of ocular central nervous system (CNS) lymphoma.Retrospective study 44 patients over a 10-year period.A total 36 women six men, mean age 54 years (range: 36-90 years), were included. The time interval between onset symptoms diagnosis was 40 months 1-144 months). Ocular involvement bilateral in 84% cases. Laser flare photometry readings averaged 9.6 photons/ms (2.9-78.3 photons/ms). Vitritis constant. Funduscopy revealed RPE...
To determine the value of IL-10 measurement in aqueous humor (AH) for screening primary intraocular lymphoma (PIOL).One hundred consecutive diagnostic or therapeutic vitrectomies were performed patients with uveitis. During surgery, 100 microL both AH and pure vitreous was taken. levels determined a standard quantitative sandwich enzyme immunoassay technique. Patients distributed two groups: 51 proven PIOL, 108 uveitis divided into 74 etiology 34 idiopathic Groups compared by ANOVA...
<b>Aim:</b> Severe uveitis is potentially associated with visual impairment or blindness in young patients. Therapeutic strategies remain controversial. The efficacy of interferon alpha-2a (IFN-α2a) severe uveitis, refractory to steroids and conventional immunosuppressive agents, was evaluated. <b>Patients methods:</b> Patients were included after a major relapse following corticosteroids immunosuppressants. IFN-α2a (3 million units three times week) administered subcutaneously. Efficacy...
Primary intraocular lymphoma, a non-Hodgkin's is primary central nervous system lymphoma (PCNSL). Diagnosis usually made by identifying malignant, large B lymphocytes in the vitreous, eye, brain, and cerebral spinal fluid; however, these cells are few, friable, difficult to recognize. Recently, clonal heavy chain immunoglobulin (IgH) gene rearrangement bcl-2 translocation have been reported systemic B-cell used for detection of malignant making diagnosis. The authors investigated molecular...
<b>Aim:</b> To describe the diagnostic and therapeutic management of cytomegalovirus (CMV) anterior uveitis unassociated with retinal necrosis in immunocompetent patients. <b>Methods:</b> Patients referred between 2001 2003 for unilateral, chronic, recurrent associated secondary glaucoma underwent extensive investigation including laboratory tests herpes virus infections. Specific antiviral treatment was initiated all cases level ocular inflammation evaluated during follow up....
<h3>Abstract</h3> <h3>Introduction</h3> The role of intravenous (IV) iron in chronic heart failure has been well studied, however, its acute (AHF) is less well-known. Including the recent AFFIRM-HF trial, we performed a systematic review and meta-analysis to highlight IV AHF with deficiency. <h3>Hypothesis</h3> We hypothesized that doesn’t change mortality or re-hospitalization rates patients <h3>Methods</h3> conducted randomized controlled trials (RCTs) cohort studies published from...
To evaluate the efficacy and safety of intravitreal sirolimus in treatment noninfectious uveitis (NIU) posterior segment (i.e., posterior, intermediate, or panuveitis).Phase III, randomized, double-masked, active-controlled, 6-month study with sirolimus.Adults active NIU (intermediate, panuveitis), defined as a vitreous haze (VH) score >1+. Subjects discontinued medications before baseline, except for systemic corticosteroids, which were allowed only those already receiving them at baseline...