Alvin L. Young

ORCID: 0000-0002-4365-3218
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About
Contact & Profiles
Research Areas
  • Corneal surgery and disorders
  • Glaucoma and retinal disorders
  • Retinal Diseases and Treatments
  • Ocular Surface and Contact Lens
  • Corneal Surgery and Treatments
  • Intraocular Surgery and Lenses
  • Ophthalmology and Visual Impairment Studies
  • Ocular Infections and Treatments
  • Retinal Imaging and Analysis
  • Ocular Diseases and Behçet’s Syndrome
  • Retinal and Optic Conditions
  • Ophthalmology and Eye Disorders
  • IgG4-Related and Inflammatory Diseases
  • Retinal and Macular Surgery
  • Retinopathy of Prematurity Studies
  • Cerebral Venous Sinus Thrombosis
  • Systemic Lupus Erythematosus Research
  • Cytomegalovirus and herpesvirus research
  • Traumatic Ocular and Foreign Body Injuries
  • Nasolacrimal Duct Obstruction Treatments
  • Neuroendocrine Tumor Research Advances
  • Ocular Disorders and Treatments
  • Neonatal Respiratory Health Research
  • Marine Ecology and Invasive Species
  • Connective tissue disorders research

Hong Kong Eye Hospital
2006-2025

Chinese University of Hong Kong
2016-2025

Prince of Wales Hospital
2016-2025

Alice Ho Miu Ling Nethersole Hospital
2013-2024

National Chi Nan University
2024

Weatherford College
2023

Hyogo Medical University
2021

Hospital Authority
2020

Princess of Wales Hospital
2019

Christie's
2015

The impacts of social restrictions for COVID-19 on children's vision and lifestyle remain unknown.To investigate myopia incidence, spherical equivalent refraction (SER) changes among schoolchildren during the pandemic.Two separate longitudinal cohorts children aged 6-8 years in Hong Kong were included. cohort was recruited at beginning outbreak, whereas pre-COVID-19 before pandemic. All received ocular examinations, answered a standardised questionnaire relating to their lifestyle, including...

10.1136/bjophthalmol-2021-319307 article EN British Journal of Ophthalmology 2021-08-02

<h3>Importance</h3> Early onset of myopia is associated with high later in life, and irreversible once developed. <h3>Objective</h3> To evaluate the efficacy low-concentration atropine eyedrops at 0.05% 0.01% concentration for delaying myopia. <h3>Design, Setting, Participants</h3> This randomized, placebo-controlled, double-masked trial conducted Chinese University Hong Kong Eye Centre enrolled 474 nonmyopic children aged 4 through 9 years cycloplegic spherical equivalent between +1.00 D to...

10.1001/jama.2022.24162 article EN JAMA 2023-02-14

BackgroundSpectral-domain optical coherence tomography (SDOCT) can be used to detect glaucomatous optic neuropathy, but human expertise in interpretation of SDOCT is limited. We aimed develop and validate a three-dimensional (3D) deep-learning system using volumes neuropathy.MethodsWe retrospectively collected dataset including 4877 disc cube for training (60%), testing (20%), primary validation (20%) from electronic medical research records at the Chinese University Hong Kong Eye Centre...

10.1016/s2589-7500(19)30085-8 article EN cc-by-nc-nd The Lancet Digital Health 2019-08-01

To determine the myopia prevalence in Hong Kong Chinese children and their parents.It was a population-based cross-sectional study. A total of 4257 aged 6-8 years, 5880 parents were recruited Children Eye Study. Cycloplegic autorefraction measured for children; non-cycloplegic parents. Parental educational level, children's outdoor time, near work collected by validated questionnaires.In 25.0% myopic, among them, 12.7% 6-year-olds, 24.4% 7-year-olds 36.1% 8-year-old. About 0.7% 8 years high...

10.1111/aos.14350 article EN Acta Ophthalmologica 2020-01-24
Qiao Fan Xiaobo Guo J. Willem L. Tideman Katie Williams Seyhan Yazar and 95 more S. Mohsen Hosseini Laura D. Howe Beaté St Pourcain David M. Evans Nicholas J. Timpson George McMahon Pirro G. Hysi Eva Krapohl Ya Xing Wang Jost B. Jonas Paul N. Baird Jie Jin Wang Ching‐Yu Cheng Yik-Ying Teo Tien Yin Wong Xiaohu Ding Robert Wojciechowski Terri L. Young Olavi Pärssinen Konrad Oexle Norbert Pfeiffer Joan E. Bailey‐Wilson Andrew D. Paterson Caroline C. W. Klaver Robert Plomin Christopher J. Hammond David A. Mackey Mingguang He Seang‐Mei Saw Cathy Williams Jeremy A. Guggenheim Akira Meguro Alan F. Wright Alex W. Hewitt Alvin L. Young Veluchamy A. Barathi Andres Metspalu Andrew D. Paterson Angela Döring Anthony P. Khawaja Barbara E.K. Klein Beaté St Pourcain Brian W. Fleck Caroline C. W. Klaver Caroline Hayward Cathy Williams Cécile Delcourt Chi Pui Pang Chiea Chuen Khor Ching‐Yu Cheng Christian Gieger Christopher J. Hammond Claire L. Simpson Cornelia M. van Duijn David A. Mackey David M. Evans Dwight Stambolian Emily Y. Chew E Shyong Tai Eva Krapohl Evelin Mihailov George Davey Smith George McMahon Ginevra Biino Harry Campbell Igor Rudan Ilkka Seppälä Jaakko Kaprio James F. Wilson Jamie E. Craig J. Willem L. Tideman Janina S. Ried Jean‐François Korobelnik Jeremy A. Guggenheim Jeremy Fondran Jie Jin Wang Jiemin Liao Wei Zhao Jing Xie Joan E. Bailey‐Wilson John P. Kemp Jonathan H. Lass Jost B. Jonas Jugnoo S. Rahi Juho Wedenoja Kari-Matti Mäkelä Kathryn P. Burdon Katie Williams Kay‐Tee Khaw Kenji Yamashiro Konrad Oexle Laura D. Howe Li Jia Chen Liang Xu Lindsay A. Farrer

Abstract Myopia, currently at epidemic levels in East Asia, is a leading cause of untreatable visual impairment. Genome-wide association studies (GWAS) adults have identified 39 loci associated with refractive error and myopia. Here, the age-of-onset between genetic variants these was investigated 5200 children assessed longitudinally across ages 7–15 years, along gene-environment interactions involving major environmental risk-factors, nearwork time outdoors. Specific could be categorized...

10.1038/srep25853 article EN cc-by Scientific Reports 2016-05-13

Importance Childhood myopia increased during the COVID-19 pandemic. Limited evidence exists about whether development was reversed or worsened after lockdown. Objective To determine prevalence of and its associated factors before, during, restrictions. Design, Setting, Participants This population-based, repeated cross-sectional study evaluated children aged 6 to 8 years from Hong Kong Children Eye Study between 2015 2021 in 3 cohorts: before (2015-2019), restrictions (2020), were lifted...

10.1001/jamanetworkopen.2023.4080 article EN cc-by-nc-nd JAMA Network Open 2023-03-22

Importance Astigmatism can cause blurred vision at near and distance. It is common among schoolchildren associated with ametropia. Although the COVID-19 pandemic generated a surge in myopia prevalence children, association child astigmatism remains unknown. Objective To report of refractive corneal from 2015 to 2023 explore associations between astigmatism. Design, Setting, Participants This population-based cross-sectional study stratified all primary schools registered Education Bureau...

10.1001/jamaophthalmol.2025.0205 article EN JAMA Ophthalmology 2025-03-20

<b>Background:</b> Pseudoexfoliation syndrome (PXS) is regarded as rare in people of Chinese ethnicity but the prevalence this condition not known. This epidemiology study was conducted to assess PXS cataract patients and report clinical features present. <b>Methods:</b> Prospective descriptive period from March 1999 May 2001 ophthalmology departments cluster hospitals serving a population about 1.2 million. 500 consecutive aged 60 or above attending general ophthalmic clinics with presumed...

10.1136/bjo.2003.021816 article EN British Journal of Ophthalmology 2004-01-21
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