A5058157026- Corneal surgery and disorders
- Ophthalmology and Visual Impairment Studies
- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Corneal Surgery and Treatments
- Retinopathy of Prematurity Studies
- Intraocular Surgery and Lenses
- Allergic Rhinitis and Sensitization
- Ocular and Laser Science Research
- Visual perception and processing mechanisms
- Respiratory and Cough-Related Research
- Ocular Oncology and Treatments
- Vestibular and auditory disorders
First Affiliated Hospital of Anhui Medical University
2024
Anhui Medical University
2024
Wenzhou Medical University
2021-2024
Affiliated Eye Hospital of Wenzhou Medical College
2021-2024
Chinese University of Hong Kong
2019-2023
Hyogo Medical University
2021
Sir Run Run Shaw Hospital
2021
Zhejiang University
2021
Secondhand smoking is a risk to adult ocular health, but its effect on children's development not known.To assess the association between choroidal thickness and secondhand exposure in children.Children aged 6 8 years were consecutively recruited from January 2016 July 2017 population-based Hong Kong Children Eye Study at Chinese University of Centre. All participants underwent detailed ophthalmic investigations. Choroidal was measured by swept-source optical coherence tomography, with...
Objective To investigate the associations of single-nucleotide polymorphisms (SNPs) in ZC3H11B, ZFHX1B, VIPR2 , SNTB1 and MIPEP genes with severities myopia Chinese populations. Methods Based on previous genome-wide association studies, five SNPs ( ZC3H11B rs4373767, ZFHX1B rs13382811, rs2730260, rs7839488 rs9318086) were selected for genotyping a cohort 2079 subjects: 252 extreme myopia, 277 high 393 moderate 366 mild 791 non-myopic controls. Genotyping was performed by TaqMan assays....
Objective To investigate the associations of multiple single-nucleotide polymorphisms (SNPs) with severities and endophenotypes myopia in children. Methods A total 3300 children aged 5–10 years were recruited: 137 moderate high (SE≤−3.0D), 670 mild (−3.0D<SE≤−0.5D) 2493 controls (SE>−0.5D). 13 SNPs genes/loci selected for genotyping all subjects using TaqMan assays. Associations between each SNP ocular traits (spherical equivalent (SE), axial length (AL) corneal radius (CR)) analysed....
Purpose: To evaluate the association between single-nucleotide polymorphisms (SNPs) in ZC3H11B, RSPO1, C3orf26, GJD2, ZNRF3, and WNT7B genes myopia endophenotypes children. Methods: Seven SNPs identified previous genome-wide studies of axial length (AL) were genotyped 2883 Southern Han Chinese Multiple linear regression analyses conducted to genotype with AL, spherical equivalent (SE), corneal curvature (CC), central thickness (CCT). Results: Two SNPs—namely, rs12144790 RSPO1 (allele T, P =...
Aims To assess the association of single-nucleotide polymorphisms (SNPs) with myopia progression for polygenic risk prediction in children. Methods Six SNPs ( ZC3H11B rs4373767, ZFHX1B rs13382811, KCNQ5 rs7744813, MET rs2073560, SNTB1 rs7839488 and GJD2 rs524952) were analysed 1043 school children, who completed 3-year follow-up, using TaqMan genotyping assays. SNP associations spherical equivalent (SE) by logistic regression. Polygenic scores (PRS) applied computing sum alleles multiple...
To determine the factors related to preoperative ocular characters that are predictive of insufficient vault (<250 µm) after implantable collamer lens (ICL V4c; STAAR Surgical) implantation.
Purpose: To identify gene variants associated with anisometropia development in children. Methods: This is a population-based, cross-sectional, and longitudinal genetic association study involving 1057 children aged 6 to 10 years both baseline 3-year follow-up data. Six single nucleotide polymorphisms (SNPs), ZC3H11B rs4373767, ZFHX1B rs13382811, KCNQ5 rs7744813, SNTB1 rs7839488, PAX6 rs644242, GJD2 rs524952 were analyzed all Anisometropia was defined by an interocular difference SE of ≥1...
To compare astigmatic correction among cross-assisted small-incision lenticule extraction (SMILE), femtosecond laser-assisted in situ keratomileusis (FS-LASIK), and transepithelial photorefractive keratectomy (transPRK).The Eye Hospital of Wenzhou Medical University, Zhejiang, China.Prospective comparison study.154 right eyes 154 patients with astigmatism -1.00 to -2.75 diopters (D) were included this study. 64 eyes, 42 48 receiving SMILE, FS-LASIK, transPRK, respectively. The SMILE group...