A5101668018- Ophthalmology and Visual Impairment Studies
- Corneal surgery and disorders
- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Retinal and Optic Conditions
- Retinopathy of Prematurity Studies
- Head and Neck Surgical Oncology
- Machine Learning in Bioinformatics
- Cytomegalovirus and herpesvirus research
- Cancer-related gene regulation
- Corneal Surgery and Treatments
- Head and Neck Anomalies
- Nasolacrimal Duct Obstruction Treatments
- Economic and Financial Impacts of Cancer
- Protein Structure and Dynamics
- Medication Adherence and Compliance
- Renal Diseases and Glomerulopathies
- Telemedicine and Telehealth Implementation
- Advanced Machining and Optimization Techniques
- Advanced Numerical Analysis Techniques
- Ocular Infections and Treatments
- Intraocular Surgery and Lenses
- HIV, Drug Use, Sexual Risk
- Hemophilia Treatment and Research
Chinese University of Hong Kong
2020-2025
Nanjing Xiaozhuang University
2024
Hong Kong Eye Hospital
2022-2024
University of Iowa
2004-2023
Hyogo Medical University
2021
Jimei University
2020
Tulane University
2018
The impacts of social restrictions for COVID-19 on children's vision and lifestyle remain unknown.To investigate myopia incidence, spherical equivalent refraction (SER) changes among schoolchildren during the pandemic.Two separate longitudinal cohorts children aged 6-8 years in Hong Kong were included. cohort was recruited at beginning outbreak, whereas pre-COVID-19 before pandemic. All received ocular examinations, answered a standardised questionnaire relating to their lifestyle, including...
<h3>Importance</h3> Early onset of myopia is associated with high later in life, and irreversible once developed. <h3>Objective</h3> To evaluate the efficacy low-concentration atropine eyedrops at 0.05% 0.01% concentration for delaying myopia. <h3>Design, Setting, Participants</h3> This randomized, placebo-controlled, double-masked trial conducted Chinese University Hong Kong Eye Centre enrolled 474 nonmyopic children aged 4 through 9 years cycloplegic spherical equivalent between +1.00 D to...
Importance Astigmatism can cause blurred vision at near and distance. It is common among schoolchildren associated with ametropia. Although the COVID-19 pandemic generated a surge in myopia prevalence children, association child astigmatism remains unknown. Objective To report of refractive corneal from 2015 to 2023 explore associations between astigmatism. Design, Setting, Participants This population-based cross-sectional study stratified all primary schools registered Education Bureau...
Reinforcement learning (RL) has recently been introduced to interactive recommender systems (IRS) because of its nature from dynamic interactions and planning for long-run performance. As IRS is always with thousands items recommend (i.e., actions), most existing RL-based methods, however, fail handle such a large discrete action space problem thus become inefficient. The work that tries deal the by utilizing deep deterministic policy gradient framework suffers inconsistency between...
Importance Childhood myopia increased during the COVID-19 pandemic. Limited evidence exists about whether development was reversed or worsened after lockdown. Objective To determine prevalence of and its associated factors before, during, restrictions. Design, Setting, Participants This population-based, repeated cross-sectional study evaluated children aged 6 to 8 years from Hong Kong Children Eye Study between 2015 2021 in 3 cohorts: before (2015-2019), restrictions (2020), were lifted...
The increasing prevalence of myopia worldwide presents a significant public health challenge. A key strategy to combat is with early detection and prediction in children as such examination allows for effective intervention using readily accessible imaging technique. To this end, we introduced DeepMyopia, an artificial intelligence (AI)-enabled decision support system detect predict onset facilitate targeted interventions at risk routine retinal fundus images. Based on deep learning...
Several interventions exist for treating myopia progression in children. While these interventions' efficacy has been studied, their cost-effectiveness remains unknown and not compared.
To investigate the associations of lung function with glaucoma and related traits, explore interactions between genetic risk function, assess causal relationships using Mendelian randomization (MR). This cross-sectional study involved 85,369 participants measurements at baseline from UK Biobank. Associations parameters traits were tested by multivariable logistic linear regression. Two-sample MR analyses conducted summary statistics large datasets. Forced vital capacity (FVC), forced...
Abstract The denitrifying deep-bed filter, as an advanced treatment technology for upgrading wastewater plants (WWTPs), is widely employed in the secondary effluent of facilities. In this study, three shallow filters were developed to efficiently eliminate total nitrogen, ammonia nitrates, and suspended solids (SS) from municipal WWTPs’ effluent. Sodium acetate was utilized carbon source assess denitrification effects with different filter materials (quartz sand, polycaprolactone (PCL),...
Importance Secondhand smoke (SHS) exposure potentially threatens ocular health; however, its association with myopia is unknown. Objective To examine the between SHS and childhood myopia. Design, Setting, Participants Cross-sectional data from population-based Hong Kong Children Eye Study were used. Data collected March 5, 2015, to September 12, 2021, at The Chinese University of Center. included children aged 6 8 years. was evaluated using a validated questionnaire. All participants...
Aims To investigate the associations of genetic variants previously linked to axial length (AL) and spherical equivalent refraction (SE) in adults with refractive error related endophenotypes children, at baseline 3-year follow-up. Methods 15 candidate single-nucleotide polymorphisms (SNPs), selected from previous Genome-Wide Association Studies meta-analyses, were genotyped 2819 Chinese who had undergone follow-up cycloplegic refraction, ocular biometry health examinations. Linear...
Importance Parental astigmatism is a factor associated with risk for development of child astigmatism; however, the magnitude association has not been determined. Objective To determine between parental and astigmatism. Design, Setting, Participants This population-based, cross-sectional study included participants from familial trios, each comprising aged 6 to 8 years both parents, recruited Hong Kong Children Eye Study. No restriction criteria were set on children in terms refractive...