A5115053691- Graph Theory and Algorithms
- Corrosion Behavior and Inhibition
- Hydrogen embrittlement and corrosion behaviors in metals
- Inflammasome and immune disorders
- Recommender Systems and Techniques
- Erosion and Abrasive Machining
- Telomeres, Telomerase, and Senescence
- Atherosclerosis and Cardiovascular Diseases
- Single-cell and spatial transcriptomics
- Clusterin in disease pathology
- Cancer, Lipids, and Metabolism
- Advanced Image and Video Retrieval Techniques
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Neuroinflammation and Neurodegeneration Mechanisms
- Machine Learning in Healthcare
- Privacy-Preserving Technologies in Data
- Data Management and Algorithms
Capital Medical University
2024-2025
Huazhong University of Science and Technology
2013-2024
Purpose: Novel collagenase IV (ColIV) and clusterin (CLU)-modified polycaprolactone-polyethylene glycol (PCL-PEG) nanoparticles that load doxorubicin (DOX) were designed fully evaluated in vitro vivo. Methods: PCL-PEG-ColIV was synthesized by linking PCL-PEG ColIV through a carbodiimide method. DOX-loaded (DOX-PCL-PEG-ColIV) self-assembly prepared, followed noncovalently adsorbing CLU on the DOX-PCL-PEG-ColIV surface to obtain /CLU nanoparticles, which can penetrate tumor extracellular...
Due to the high complexity of constructing exact k -nearest neighbor graphs, approximate construction has become a popular research topic. The NN-Descent algorithm is one representative in-memory algorithms. To effectively handle large datasets, existing state-of-the-art solutions combine divide-and-conquer approach and algorithm, where datasets are divided into multiple partitions, subgraph constructed for each partition before all subgraphs merged, reducing memory pressure significantly....