A5100326763- Microgrid Control and Optimization
- Mining Techniques and Economics
- Belt Conveyor Systems Engineering
- Single-cell and spatial transcriptomics
- Mineral Processing and Grinding
- Genetics, Aging, and Longevity in Model Organisms
- Epigenetics and DNA Methylation
- Fault Detection and Control Systems
- Advanced Sensor and Control Systems
- Power Systems and Renewable Energy
- Adipose Tissue and Metabolism
- Extracellular vesicles in disease
- Optimal Power Flow Distribution
- Industrial Technology and Control Systems
- Telomeres, Telomerase, and Senescence
- Frequency Control in Power Systems
- Genomics and Chromatin Dynamics
- Dietary Effects on Health
- Immune cells in cancer
- Safety and Risk Management
- Microbial Inactivation Methods
- Industrial Engineering and Technologies
- Electricity Theft Detection Techniques
- Lightning and Electromagnetic Phenomena
- Fire Detection and Safety Systems
Ingenierie des Materiaux polymeres
2025
Sichuan University
2025
Beijing Institute of Genomics
2020-2024
Chinese Academy of Sciences
2018-2024
Shanghai Center For Bioinformation Technology
2022-2024
University of Chinese Academy of Sciences
2018-2024
Liaoning Technical University
2023-2024
University of Shanghai for Science and Technology
2024
Tsinghua University
2021-2024
Institute of Electrical Engineering
2022
Regenerative capacity declines throughout evolution and with age. In this study, we asked whether metabolic programs underlying regenerative capability might be conserved across species, if so, such drivers harnessed to promote tissue repair. To end, conducted metabolomic analyses in two vertebrate organ regeneration models: the axolotl limb blastema antler stem cells. further reveal why young individuals have higher than elderly, also constructed profiles for primate juvenile aged tissues,...
Epigenetic clocks are accurate predictors of human chronological age based on the analysis DNA methylation (DNAm) at specific CpG sites. However, a systematic comparison between data and other omics datasets has not yet been performed. Moreover, available DNAm with limited ethnic representation. To address these knowledge gaps, we generated analyzed from two independent Chinese cohorts, revealing age-related changes. Additionally, aging clock (iCAS-DNAmAge) group DNAm-based multi-modal for...
Aging is a major risk factor for many diseases, especially in highly prevalent cardiopulmonary comorbidities and infectious diseases including Coronavirus Disease 2019 (COVID-19). Resolving cellular molecular mechanisms associated with aging higher mammals therefore urgently needed. Here, we created young old non-human primate single-nucleus/cell transcriptomic atlases of lung, heart artery, the top tissues targeted by SARS-CoV-2. Analysis cell type-specific aging-associated transcriptional...
The primate frontal lobe (FL) is sensitive to aging-related neurocognitive decline. However, the aging-associated molecular mechanisms remain unclear. Here, using physiologically aged non-human primates (NHPs), we depicted a comprehensive landscape of FL aging with multidimensional profiling encompassing bulk and single-nucleus transcriptomes, quantitative proteome, DNA methylome. Conjoint analysis across these neuropathological layers underscores nuclear lamina heterochromatin erosion,...
Smart grids face more cyber threats than before with the integration of photovoltaic (PV) systems. Data-driven-based machine learning (ML) methods have been verified to be effective in detecting attacks power electronics devices. However, standard ML solution requires centralized data collection and processing, which is becoming infeasible applications due efficiency issues increasing privacy concerns. In this letter, we propose a novel decentralized framework for false injection (FDI) on...
Age-dependent loss of skeletal muscle mass and function is a feature sarcopenia, increases the risk many aging-related metabolic diseases. Here, we report phenotypic single-nucleus transcriptomic analyses non-human primate aging. A higher transcriptional fluctuation was observed in myonuclei relative to other interstitial cell types, indicating susceptibility fiber We found downregulation FOXO3 aged muscle, identified as hub transcription factor maintaining homeostasis. Through establishment...
As the proportion of renewable energy (RE) increases, inertia and primary frequency regulation (FR) capability power system decrease. Thus, ensuring security in scheduling model has become a new technical requirement systems with high share RE. Due to shortage conventional synchronous generators, support multi-source converters an indispensable part resources, especially variable-speed wind turbine generation (WTG) battery storage (BES). Quantitative expression FR is necessary construct...
Abstract Diverse individuals age at different rates and display variable susceptibilities to tissue aging, functional decline aging-related diseases. Centenarians, exemplifying extreme longevity, serve as models for healthy aging. The field of human aging longevity research is rapidly advancing, garnering significant attention accumulating substantial data in recent years. Omics technologies, encompassing phenomics, genomics, transcriptomics, proteomics, metabolomics microbiomics, have...
Battery energy storage systems (BESSs) can provide instantaneous support for frequency regulation (FR) because of their fast response characteristics. However, purely pursuing a better FR effect calls continually rapid cycles BESSs, which shortens lifetime and deteriorates the operational economy. To coordinate lifespan savings effect, this paper presents control strategy BESSs based on fuzzy logic hierarchical controllers. The controller improves by adjusting charging/discharging power BESS...
Reasonable production capacity is related to the economic benefits of an open-pit coal mine. This study analyzes relationship between working face length, annual advancing speed and capacity. It constructs a function model. Take Baorixile mine as example. The remaining unmined parts are divided into four regions, range in each region analyzed by established model determined respectively. On this basis, three mining district division plans proposed. By analyzing comparing stripping ratio,...
This paper investigates an integrated process for design of the control system a small quadrotor. A twelve degree freedom dynamic model oblique cross quadrotor is first established. Then, to cope with quadrotor's nonlinear and under-actuated characteristics, Active Disturbance Rejection Control (ADRC) systems are designed. Moreover, apply conveniently, ADRC simplified as linear systems, including state error feedback (LSEF) extended observer (LESO). Some simulations experiments carried out...
A dynamic optimization method was created to address the production schedule issue in an open-pit coal mine while taking into account characteristics of fuzzy structured element. The mining capacities all “geologically optimal push-back bodies” were then examined using moving cove method. One most crucial elements process scheduling is pricing. As a result, this work also presents technique for that incorporates prediction economic time series and generation indices. An appropriate model...
Machine failure modes are presenting a major burden to the operator, plant, and enterprise causing significant downtime, labor cost, reduced revenue. New technologies emerging over past years monitor machine’s performance, detect isolate incipient failures or faults, take appropriate actions mitigate such detrimental events. This paper addresses development application of novel Prognostics Health Management (PHM) prototype machining process (a screw-tightening machine). The enabling built...
The large number of distributed generations connected to the power grid brings problems reverse flow and voltage rise. Due existence "negative regulating effect", traditional on-load tap changer (OLTC) needs reactive compensation device make good regulation. In this paper, flexible OLTC with back-to-back source converter (BTB-VSC) technology can generate a certain without device, which achieve better regulation effect. Meanwhile, based on principle sensitivity partition, we propose...
The performance of Automatic Fault Detection and Diagnostics (AFDD) algorithms to identify faults in complex building Heating Ventilation Air-Conditioning (HVAC) systems depend on the appropriateness features. This paper proposes a knowledge-discovery approach for discovering characteristic features using Multi-Objective Clustering Rapid Centroid Estimation (MOC-RCE). proposed method has been tested experimental fault data from American Society Heating, Refrigerating Engineers (ASHRAE)...
Microgrid has attracted much attention in recent years thanks to the promise of mitigating voltage drop and reducing line loss grid from a combination distributed generations (DG). Detailed analyses Microgrid's radial network are carried out considering DG's effect on losses regulation. A combined graph-based GA (Genetic Algorithm) new method is proposed calculate optimal allocation sizing for DG Microgrid. This novel based large number equations analysis constraints including boundary...
With increasing number of cables adopted in 10kV distribution system, numbers OHL-cable hybrid lines occur networks. The power supply is interrupted frequently due to insulation breakdown caused by transient overvoltage Accordingly, characteristics behavior during line energization are investigated this paper. amplitude and frequency with different cable shares studied. In the meantime, 100 simulations performed considering randomness closing timings circuit breakers (CB). Statistical...