A5012941295- Magnolia and Illicium research
- Cancer, Lipids, and Metabolism
- Advanced NMR Techniques and Applications
- 14-3-3 protein interactions
- Hippo pathway signaling and YAP/TAZ
- Plant Physiology and Cultivation Studies
- Radiomics and Machine Learning in Medical Imaging
- Plant Molecular Biology Research
- Ferroptosis and cancer prognosis
- Cervical Cancer and HPV Research
- Molecular spectroscopy and chirality
- Atomic and Subatomic Physics Research
- Cancer Genomics and Diagnostics
- Plant Reproductive Biology
- Cancer Immunotherapy and Biomarkers
- Inflammatory Biomarkers in Disease Prognosis
Jiaxing University
2021-2024
Harbin Medical University
2024
Third Affiliated Hospital of Harbin Medical University
2024
Qingdao Agricultural University
2024
Fudan University Shanghai Cancer Center
2022
Abstract Background Ovarian cancer (OVCA) is prevalent in female reproductive organs. Despite recent advances, clinical outcomes remain poor, warranting fresh treatment avenues. Honokiol has an inhibitory effect on proliferation, invasion, and survival of cells vitro vivo. Therefore, this study intended to explore specific molecular mechanism by which honokiol affected OVCA progression. Methods Bioinformatics analyzed the drug that bound OTU deubiquitinase, ubiquitin aldehyde binding 2...
Summary Tree peony ( Paeonia suffruticosa ) undergoes bud endodormancy, and gibberellin (GA) pathway plays a crucial role in dormancy regulation. Recently, key DELLA protein PsRGL1 has been identified as negative regulator of release. However, the mechanism GA signal to break remains unknown. In this study, yeast two‐hybrid screened PsSOC1 interacting with through its MADS domain, interaction was using pull‐down luciferase complementation imaging assays Transformation tree hybrid poplar...
Abstract Background Ovarian cancer (OVCA) stands as one of the most fatal gynecological malignancies. Honokiol (HNK) has been substantiated by numerous studies for its anti‐tumor activity against malignancies including OVCA. Consequently, this work was designed to elucidate impact HNK‐mediated modulation YAP/TAZ pathway on biological functions OVCA cells. Methods cells were subjected treatment with varying concentrations (0, 25, 50, 75, and 100 μM) HNK, concomitant administration YAP agonist...
Unlike patients with lung adenocarcinoma, squamous cell carcinoma (LUSC) do not derive significant benefits from targeted therapy. In recent years, immunotherapy has revolutionized the treatment approach for LUSC. However, all this type of cancer respond to immunotherapy, necessitating identification effective biomarkers predict survival prognosis and evaluate efficacy PD-1 inhibitors.
Objective: This study aimed to compare the diagnostic value of R-way, 2011 International Federation for Cervical Pathology and Colposcopy (IFCPC), Reid colposcopy evaluation system high-grade squamous intraepithelial lesions cervical cancer (HSIL+). Methods: A total 987 cases were referred vaginal microscopic examination, using R-way system, IFCPC capabilities methods detecting HSIL+ compared. Results: Using biopsy or conization as gold standard, in 170 women (17.2%) had histologically...