A5039315244- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Neuroscience and Neural Engineering
- Cancer Cells and Metastasis
- Pelvic floor disorders treatments
- Urinary Bladder and Prostate Research
- Pharmacological Effects and Toxicity Studies
- Chronic Myeloid Leukemia Treatments
- Hippo pathway signaling and YAP/TAZ
- Cellular Mechanics and Interactions
- Chronic Lymphocytic Leukemia Research
- Sexual function and dysfunction studies
- Drug Transport and Resistance Mechanisms
- Nerve injury and regeneration
- Epilepsy research and treatment
- SARS-CoV-2 detection and testing
- Acute Myeloid Leukemia Research
- Axon Guidance and Neuronal Signaling
- COVID-19 and healthcare impacts
- Lung Cancer Treatments and Mutations
Huazhong University of Science and Technology
2016-2025
Wuhan Children's Hospital
2025
Tongji Hospital
2020-2024
Central Hospital of Wuhan
2020
Beijing Institute of Technology
2019
University of Bonn
2003
BackgroundPatients on dialysis were susceptible to coronavirus disease 2019 (COVID-19) and prone severe clinical characteristics after infection; acute kidney injury was related mortality in COVID-19 cases. Limited is known about the of patients with end-stage renal not requiring replacement therapy (RRT).
To analyze the molecular genetic spectrum of children with acute myeloid leukemia (AML), and explore its correlation clinical characteristics prognosis. The data 116 newly diagnosed AML in Wuhan Children's Hospital from September 2015 to August 2022 were retrospectively analyzed. Fisher's exact test was used gene mutations features, Kaplan-Meier curve influences on NRAS (22%), KRAS (14.9%), KIT (14.7%) most common abnormalities AML. Children KIT, CEBPA GATA2 showed a higher median onset-age...
Abstract Despite decades of significant progress in understanding the molecular mechanisms malignant tumorigenic cells, it remains elusive what these cells are and controls growth cells. Recently, we have mechanically selected grown highly tumor-repopulating (TRCs), a small sub-population cancer by culturing single soft fibrin matrices. However, is unclear regulates TRC besides Sox2. Here show that nuclear protein 1 (Nupr1), independent Sox2, downregulated TRCs melanoma, ovarian breast...
BackgroundSotorasib has been approved for the treatment of adult patients with KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer (NSCLC). Due to limitations clinical trials, potential adverse events (AEs) and long-term safety issues cannot be detected. The presented study aimed evaluate sotorasib-associated AEs using FDA Adverse Event Reporting System (FAERS) database.MethodsPost-marketing AE reports sotorasib in database were collected analysis. Disproportionality...
Abstract ‘Recurrence’ of coronavirus disease 2019 (COVID-19) has triggered numerous discussions scholars at home and abroad. A total 44 recurrent cases COVID-19 32 control admitted from 11 February to 29 March 2020 Guanggu Campus Tongji Hospital affiliated Medical College Huazhong University Science Technology were enrolled in this study. All the classified as mild moderate when patients for second time. The gender mean age both (recurrent control) similar. At least one concomitant was...
To mimic the nature stretch of axon, we developed a multiple channel device which can apply mechanical to neural axon. This with four cell culture chambers and adjustable speed, could be used screening speed parameters potential nutrition factors that facilitate regeneration neuron fibers in vitro. The current design range from 0.25um (min) 50um (max) for each step, covers physiological pathological speed. increased samples stepping ranges allow sophisticated experiments performed this new...
Objective: To analyze the clinical features and spinal lesions related to micturitionin of chronic prostatitis/chronic pelvic pain syndrome(CP/CPPS) patients. Methods: Patients with CP/CPPS were enrolled this study at outpatient department Tongji Hospital between January June 2019. The data was collected analyzed, including lower urinary tract symptoms(LUTS), bowel syndrome over different parts body, as well dysfunction, organ morphological changes demonstrated by MRI. potential role in...