A5101732073- Allergic Rhinitis and Sensitization
- Monoclonal and Polyclonal Antibodies Research
- Chemokine receptors and signaling
- Contact Dermatitis and Allergies
- Entomological Studies and Ecology
- Systemic Lupus Erythematosus Research
- Immune Response and Inflammation
- T-cell and B-cell Immunology
- Advanced Biosensing Techniques and Applications
- Adolescent and Pediatric Healthcare
- Knee injuries and reconstruction techniques
- Traumatic Brain Injury and Neurovascular Disturbances
- Immunotherapy and Immune Responses
- Intracerebral and Subarachnoid Hemorrhage Research
- Autoimmune and Inflammatory Disorders Research
- Osteoarthritis Treatment and Mechanisms
- Immunodeficiency and Autoimmune Disorders
- Metabolomics and Mass Spectrometry Studies
- Lower Extremity Biomechanics and Pathologies
- Protein purification and stability
- Family and Disability Support Research
University of Alberta
2023
University of North Carolina at Chapel Hill
2008-2009
Duke Medical Center
1999
Duke University Hospital
1999
Summary Recruitment of immune cells to infection sites is a critical component the host response pathogens. This process facilitated partly through interactions chemokines with cognate receptors. Here, we examine importance fractalkine (CX3CL1) receptor, CX3CR1, which regulates function and trafficking macrophages dendritic cells, in host's ability control respiratory infections Mycobacterium tuberculosis or Francisella tularensis. Following low-dose aerosol challenge M. tuberculosis,...
164 Acute renal allograft rejection is an intense cellular immune response marked by infiltration of circulating leukocytes into the inflamed graft. Leukocyte recruitment from circulation to sites inflammation involves a cascade molecular interactions which includes initial capture and rolling cells mediated selectins, followed integrin-mediated adhesion stable arrest. During this process, become activated through stimulation G-protein coupled chemokine receptors also act facilitate...