A5100451657- RNA modifications and cancer
- Lung Cancer Treatments and Mutations
- Cancer Genomics and Diagnostics
- Clusterin in disease pathology
- Functional Brain Connectivity Studies
- Suicide and Self-Harm Studies
- Autophagy in Disease and Therapy
- CAR-T cell therapy research
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Function and Risk Factors
- Child and Adolescent Psychosocial and Emotional Development
- Psychosomatic Disorders and Their Treatments
- Multiple Myeloma Research and Treatments
- Sperm and Testicular Function
- Cardiomyopathy and Myosin Studies
- Mental Health Research Topics
- Hepatitis C virus research
- Remote Sensing and Land Use
- Hepatitis B Virus Studies
- Ferroptosis and cancer prognosis
- Respiratory viral infections research
- Insect Resistance and Genetics
- Immune Response and Inflammation
- Advanced MRI Techniques and Applications
- Cardiac Imaging and Diagnostics
Shandong Mental Health Center
2022-2025
Sichuan University
2020-2025
West China Hospital of Sichuan University
2024-2025
Shandong University
2013-2025
Hainan General Hospital
2023-2025
Chinese PLA General Hospital
2023-2025
Zhejiang University
2021-2024
University of Michigan
2021-2024
Beijing University of Technology
2011-2024
Shanghai Changzheng Hospital
2022-2024
Abstract This study aimed to develop and validate a predictive model determine the risk of in-hospital mortality in patients with acute paraquat poisoning. retrospective observational cohort included 724 poisoning whose clinical data were collected within 24 h admission. The primary outcome was mortality. Patients randomly divided into training validation cohorts (7/3 ratio). In cohort, least absolute shrinkage selection operator regression models used for dimension reduction feature...
Objective This study focused on the relationship between achievement motivation and college students’ general self-efficacy, aimed to explore mechanism of action self-efficacy. Methods Through convenience sampling, 1,076 students were investigated from Anhui Province in China. Achievement motivation, perceived social support, sports participation evaluated using standard scales. For data analysis, Pearson’s correlation structural equation model test, bias-corrected percentile Bootstrap...
Abstract Background Changes in vascular function are closely associated with the development of cardiovascular disease (CVD). Pulse wave velocity (PWV) is a potential indicator dysfunction; it allows noninvasive assessment arterial stiffness. Currently, evidence for effects different classes antidiabetic drugs on stiffness remains limited. In this study, network meta‐analysis (NMA) was performed to explore associations between changes and first‐line by evaluating PWV patients metabolic...
Teratozoospermia is usually associated with defective spermiogenesis and a disorder considerable genetic heterogeneity. Although previous studies have identified several teratozoospermia-associated genes, the etiology remains unknown for majority of affected men. Here, we homozygous missense mutation compound heterozygous CCIN in patients suffering from teratozoospermia. encodes cytoskeletal protein Calicin that involved formation maintenance highly regular organization calyx mammalian...
Background: Living donor liver transplantation (LDLT) has become a widely accepted alternative to deceased (DDLT). Nevertheless, the available meta-analyses shed light on perplexing issue regarding which transplant is better. Therefore, we performed an umbrella review summarize and evaluate evidence from current meta-analyses. Methods: Two independent reviewers conducted search of PubMed, Embase, Web Science, Cochrane Database Systematic Reviews inception 1 June 2024. The methodological...
This study aimed to develop functional fruit wines using whole fruit, pulp, and peels from green bananas. The boiled banana homogenates were mixed with cane sugar before wine fermentation. Quality parameters, phenolic compounds, flavor components, antioxidative properties of the peel (GBPW), pulp (GBMW), (GBW) determined. High-performance liquid chromatography was used determine phytochemical compounds in three wines, components further analyzed headspace solid-phase microextraction combined...
Abstract Non-suicidal self-injury (NSSI) in adolescents is becoming a widespread health issue. Recent studies have suggested that repetitive NSSI crucial and can be conceptualized as an “addictive behavior.” The aim of this cross-sectional study was to explore the network relationships among child maltreatment, anxiety, addictive adolescents. In total, 542 (14.07 ± 2.15 years old, 18.6% males) with behavior completed related questionnaires. Two types psychometric approaches were used analyze...
Abstract Background Childhood trauma is a pivotal risk factor for adolescent depression. While the association between childhood and depression well-established, mediating role of self-concept has not been acknowledged. Specifically, limited attention paid to how maltreatment impacts through physical social self-concept, both in clinical community samples. This study aims investigate distinct cumulative affects depression, as well potential their relationships. Methods We recruited 227...
The goal of this study was to improve the solubility and oral bioavailability tamibarotene by complexing it with hydroxypropyl-β-cyclodextrin (HP-β-CD). inclusion complex (Am80-HP-β-CD) prepared through a freeze-drying method at mole ratio 1:1 (Am80: HP-β-CD). Fourier transform infrared spectroscopy (FT-IR) differential scanning calorimetry (DSC) indicated formation Am80-HP-β-CD. In vitro dissolution studies showed that percentage Am80-HP-β-CD improved substantially compared Am80. An...
Abstract Background Drug resistance poses a significant challenge in cancer treatment, particularly as leading cause of therapy failure. Cisplatin, the primary drug for lung adenocarcinoma (LUAD) chemotherapy, shows effective treatment outcomes. However, development against cisplatin is major obstacle. Therefore, identifying genes resistant to and adopting personalized could significantly improve patient Methods By examining transcriptome data cisplatin-resistant LUAD cells from GEO...
Background: Sleep problems are common during pregnancy.Few studies currently available regarding the determinants of sleep quality among pregnant women in China.The aim present study was to (a) calculate prevalence disorder pregnancy, (b) examine difference three trimesters, and (c) identify women.Methods: This designed as a cross-sectional survey.500 were recruited at outpatient department obstetrics gynecology two teaching hospitals central China.Five self-report questionnaires used for...
Epigenetics plays a crucial role in regulating gene expression during adolescent brain maturation. In adolescents with depression, microglia-mediated chronic neuroinflammation may contribute to the activation of cellular signaling cascades and cause central synapse loss. However, exact mechanisms underlying epigenetic regulation leading depression remain unclear. this study, we found that polycomb group 1 (PCGF1), an important regulator, was decreased both plasma major depressive disorder...
The vacuolar H+-translocating ATPase (V-ATPase) is the major proton pump for intra-organellar acidification. Therefore, integrity of V-ATPase closely associated with cellular homeostasis, and mutations in genes encoding components assembly factors have been reported certain types diseases. For instance, recurrent ATP6AP1, a gene accessory protein, cancers immunodeficiency. With aim studying V-ATPase-related using yeast model system, we report that Big1 another homolog ATP6AP1 cells,...
Bacterial infection is a major threat to global public health, and can cause serious diseases such as bacterial skin foodborne diseases. It essential develop new method rapidly diagnose clinical multiple infections monitor food microbial contamination in production sites real-time. In this work, we developed 4-mercaptophenylboronic acid gold nanoparticles (4-MPBA-AuNPs)-functionalized hydrogel microneedle (MPBA-H-MN) for bacteria detection interstitial fluid. MPBA-H-MN could conveniently...