A5100659217- Child and Adolescent Psychosocial and Emotional Development
- Animal Genetics and Reproduction
- Genetics and Neurodevelopmental Disorders
- Neuroendocrine regulation and behavior
- Maternal Mental Health During Pregnancy and Postpartum
- Early Childhood Education and Development
- CRISPR and Genetic Engineering
- Autism Spectrum Disorder Research
- Epigenetics and DNA Methylation
- Neural and Behavioral Psychology Studies
- Mental Health Research Topics
- Pluripotent Stem Cells Research
- Wnt/β-catenin signaling in development and cancer
- Muscle metabolism and nutrition
- Endoplasmic Reticulum Stress and Disease
- Stress Responses and Cortisol
- RNA Interference and Gene Delivery
- Advanced biosensing and bioanalysis techniques
- Hedgehog Signaling Pathway Studies
- Retinal Development and Disorders
- Multisensory perception and integration
- Aviation Industry Analysis and Trends
- Deception detection and forensic psychology
- Brain Tumor Detection and Classification
- Plant-derived Lignans Synthesis and Bioactivity
Shandong Normal University
2014-2025
Guizhou Normal University
2024-2025
Anhui Sanlian University
2024
Guangdong Medical College
2024
Second Affiliated Hospital of Nanjing Medical University
2018-2023
Huashan Hospital
2023
Fudan University
2023
Beihang University
2022
Hong Kong University of Science and Technology
2022
Zhongnan Hospital of Wuhan University
2022
Abstract Skeletal muscle stem cells, also called Satellite Cells (SCs), are actively maintained in quiescence but can activate quickly upon extrinsic stimuli. However, the mechanisms of how quiescent SCs (QSCs) swiftly remain elusive. Here, using a whole mouse perfusion fixation approach to obtain bona fide QSCs, we identify massive proteomic changes during quiescence-to-activation transition pathways such as chromatin maintenance, metabolism, transcription, and translation. Discordant...
Cardiovascular disease (CVD) is a major complication of type 2 diabetes mellitus (T2DM). In addition to traditional risk factors, psychological determinants play an important role in CVD risk. This study applied Deep Neural Network (DNN) develop prediction model and explored the bio-psycho-social contributors among patients with T2DM. From 2017 2020, 834 T2DM were recruited from Department Endocrinology, Affiliated Hospital Harbin Medical University, China. this cross-sectional study,...
Receptor-interacting protein kinase 1 (RIPK1) mediates necroptosis and inflammation in various pathophysiologies, emerging as a pharmacological target for neurodegenerative inflammatory indications. This phase I, first-in-human, placebo-controlled study evaluated the safety, pharmacokinetics (PKs), pharmacodynamics (PDs) of GFH312, an RIPK1 inhibitor, healthy adults. Subjects received GFH312 single ascending dose up to 500 mg (part I) or once-daily repeated doses 200 14 days II). PKs were...
Abstract This paper presents robustness analysis for a kind of switched cyber‐physical systems in view input‐output dynamical stability. At first, the underly definitions and input–output stability are proposed. Secondly, an algorithm, which is aimed to transform given finite into logical networks, constructed between them analyzed. Thirdly, with help approximate simulation relation, infinite approximated as systems, also Then, analyzed via aforementioned results. Finally, illustrative...
Regulation of the immune response in asthma is complex. MicroRNA-126 (miR-126) expression has been implicated this response, so we sought to determine clinical significance miR-126 measured peripheral blood. A total 80 children with acute were selected participate study and compared healthy children. The relative circulating levels, interleukin (IL)-4 Th17 cell percentage blood case group significantly higher than those control group, while interferon (IFN)-γ levels CD4 + CD25 Treg lower...
Major depressive disorder (MDD) is a leading cause of disability worldwide. Adolescence crucial period for the occurrence and development depression. There are essential distinctions between adolescent adult depression patients, etiology unclear. The interactions multiple genes in co-expression network likely to be involved physiopathology MDD. In present study, RNA-Seq data mRNA were acquired from peripheral blood MDD adolescents healthy control (HC) subjects. Co-expression modules...
<p id=p00005>Prosocial behaviour, that is, behaviour intended to benefit others, has been linked a variety of desirable traits, including positive relationships, better academic performance and lower levels antisocial behaviours. As such, the origins mechanisms underlying remarkable individual differences in prosocial are focus an increasing number studies, with numerous research consistently documenting important role parenting empathy. Notably, differentiating between cognitive emotional...
Objectives: Accelerating wound healing using continuous exogenous electrical stimulation is limited due to some serious side effects, including thermal damage. Many previous studies based on direct current contact may cause chemical burns or blisters, thereby increasing patients suffering. The aim of this study was develop a safer and more convenient pulse capacitive coupling field (PCCEF) accelerate healing. Approach: A PCCEF-generating platform self-designed facilitate promoting effects...
Numerous studies have demonstrated that both catechol-O-methyltransferase (COMT) gene and monoamine oxidase A (MAOA) been involved in aggressive behavior, as stressful life events (SLEs). However, most of available evidence was based upon single or gene-environment design, which is limited accounting for the variance a complex phenotype. This study examined possible × environment interactions between SLE (interpersonal problems academic pressure) two genetic polymorphisms (MAOA T941G COMT...
In this study, a pot experiment was carried out in greenhouse to investigate the potentials of Xerocomus badius and Serendipita indica penetrate colonize roots ryegrass (Lolium multiflorum Lam.) induce beneficial effects on seed germination seedling growth. The results showed that X. S. successfully colonized root system L. seedlings colonization rate 72.65% 88.42%, respectively. By microscopy, hyphae, chlamydospores spores produced by were observed cortex seedlings. comparison with...
The impact of high-speed rail (HSR) on urban spatial structure has attracted much attention since the 1970s. It mainly realizes change by affecting distribution population and economy. Based industry data 29 cities in Central Plains Urban Agglomeration (CPUA) located central China during 2005–2017, this paper difference-in-difference (DID) models are utilized to explore influence HSR prefecture-level at single/multicenter levels according dimensions polycentricity dispersion. main...
Introduction: Investigations of gene-environment (G×E) interactions in major depressive disorder (MDD) have been limited to hypothesis testing candidate genes while poly-gene-environmental causation has not adequately address. To this end, the present study analyzed association between three genes, two environmental factors, and MDD using a hypothesis-free approach. Methods: A logistic regression model was used analyze interaction effects; hierarchical evaluate effects different genotypes...
Continuous in-depth language research and the rapid development of teaching deepen people's understanding nature language. The focus for workers is from how to teach learn, learning result process; emphasis on teachers methods, study gradually tends learners, strategies emotions. However, in daily process, college students have serious anxiety oral learning. This based Krashen's comprehensible input hypothesis alleviate English majors. By means questionnaire, this article gave pre-designed...