A5033000269- Blood groups and transfusion
- Erythrocyte Function and Pathophysiology
- Hemoglobinopathies and Related Disorders
- Antibiotic Use and Resistance
- Blood disorders and treatments
- Ophthalmology and Visual Health Research
- Public Policy and Governance
- Genetic Associations and Epidemiology
- Public Health in Brazil
- Psychology Research and Bibliometrics
- Innovations in Medical Education
- Education Pedagogy and Practices
- Parvovirus B19 Infection Studies
- Platelet Disorders and Treatments
- Psychological Treatments and Disorders
- Patient Satisfaction in Healthcare
- Developmental and Educational Neuropsychology
- Genomics and Rare Diseases
- Cultural, Media, and Literary Studies
- Patient Safety and Medication Errors
- Urban and sociocultural dynamics
National Institutes of Health Clinical Center
2016-2024
National Institutes of Health
2020
Universidade de Santa Cruz do Sul
2011
Among 710 RHD alleles, 3 alleles have been shown to express CcEe antigens and, among 67 hybrid of the gene, 2 evolved include RHCE exons 4-9. No breakpoint region had described for such RHD-CE(4-9)-D alleles. In Kidd blood group system, JK*02N.01 null allele is found with high prevalence in Polynesian population. We investigated a self-identified Pacific Islander discrepant serologic and molecular results his C Jk
The 1000 Genomes Project provides a database of genomic variants from whole genome sequencing 2504 individuals across five continental superpopulations. This can enrich our background knowledge worldwide blood group variant geographic distribution and identify novel potential clinical significance.The was analyzed to 1) expand about distributions known variants, 2) with antigenic their association, 3) establish baseline scaffold chromosomal coordinates translate next-generation output files...
Os antimicrobianos são utilizados de forma indiscriminada na prática médica, contribuindo com a emergência cepas microbianas resistentes. Este estudo descreve auditoria realizada por análise prospectiva 846 prontuários pacientes internados no Hospital Santa Cruz, em Cruz do Sul - Rio Grande Brasil. Do total dos analisados, 134 (15,8%) receberam antimicrobianos. A foi modo interativo, intervenção e discussão o médico prescritor. Considerando-se diagnóstico presumido droga prescrita,...
Abstract Background and objectives Next generation sequencing (NGS) has promising applications in transfusion medicine. Exome (ES) is increasingly used the clinical setting, blood group interpretation an additional value that could be extracted from existing data sets. We provide first release of open‐source software tailored for this purpose describe its validation with three systems. Materials methods The DTM‐Tools algorithm was designed to analyse 1018 ES NGS files ClinSeq ® cohort....
Antimicrobials are used interchangeably in medical practice, contributing to the emergence of resistant microbial strains.This study describes antimicrobial audit performed by forecasting analysis records 846 patients at Hospital Santa Cruz, Cruz do Sul - Rio Grande Brazil.Of studied, 134 (15.8%) received antimicrobials. The was conducted interactively, with intervention and discussion prescriber. Considering presumptive diagnosis prescribed drug, it verified that 74.6% on antimicrobials...
The Scianna (SC) blood group system comprises seven antigens. They reside on the erythroblast membrane-associated glycoprotein (ERMAP). ERMAP and RHCE genes are juxtaposed to each other chromosome 1. We report a novel SC antigen.Blood samples came from patient his two sisters in Saudi Arabia. To investigate antibody specificity we used column agglutination technique soluble recombinant protein. significance of anti-SCAR was evaluated by transfusion history monocyte monolayer assay....
Abstract Background An original methodology for determining the D antigen density on red cells was published in 2000 and has been applied many publications since. This flow cytometry‐based assay remained largely unrevised utilizing monoclonal anti‐Ds that are not readily available anymore. We updated to quantify erythrocyte sites using microspheres commercially today. Methods The absolute of a frozen standard CcDEe cell, drawn 2003, fresh blood donation from same individual, 2022, an...
According to recent work group recommendations, individuals with the serologic weak D phenotypes should be RHD genotyped and molecular types 1, 2, 3, 4.0, or 4.1 treated as D+. We report an African American woman a long-standing history of metrorrhagia, who presented for infertility evaluation. Blood grouping showed AB possible subgroup A, based on mixed-field agglutination, phenotype. Results from routine red cell genotyping gene was incongruent RhCE For surgical procedure, patient hence...
Esse texto é parte do projeto de tese doutorado cuja proposta visa tomar o espaço vivo da escola como objeto análise, buscando perceber têm se constituído as relações cotidianas, que vazios podem ser apreendidos em torno dos acontecimentos ali produzem e quê promovem os documentos referentes a estas mesmas práticas. O presente pretende lançar um convite para leitores possam penetrar nas “cenas” foram dando vida ao tese.