A5022131590- Advanced Radiotherapy Techniques
- Radiation Therapy and Dosimetry
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Radiation Dose and Imaging
- Lung Cancer Diagnosis and Treatment
- Radiation Effects and Dosimetry
- Advanced X-ray and CT Imaging
- Prostate Cancer Diagnosis and Treatment
- Advances in Oncology and Radiotherapy
- Digital Radiography and Breast Imaging
- Nuclear Physics and Applications
- MRI in cancer diagnosis
- Radiation Detection and Scintillator Technologies
- Brain Metastases and Treatment
- Radiopharmaceutical Chemistry and Applications
- Glioma Diagnosis and Treatment
- Boron Compounds in Chemistry
- Advanced MRI Techniques and Applications
- Management of metastatic bone disease
- Endometrial and Cervical Cancer Treatments
- Efficiency Analysis Using DEA
- Breast Cancer Treatment Studies
- Integrated Circuits and Semiconductor Failure Analysis
- Head and Neck Cancer Studies
The General Hospital of Heraklion "Venizeleio-Pananio"
2024
The University of Texas Health Science Center at San Antonio
2010-2020
The University of Texas at San Antonio
2010-2016
University of North Carolina at Chapel Hill
2015
University of Patras
2015
The University of Texas Health Science Center at Houston
2009-2013
Radiation Oncology Associates
2009-2013
Karolinska Institutet
2011-2012
Stockholm University
2012
Nike (United States)
2011
The high dose per fraction delivered to lung lesions in stereotactic body radiation therapy (SBRT) demands calculation and delivery accuracy. inhomogeneous density the thoracic region along with small fields used typically intensity-modulated (IMRT) treatments poses a challenge accuracy of calculation. In this study we dosimetrically evaluated pre-release version Monte Carlo planning system (PEREGRINE 1.6b, NOMOS Corp., Cranberry Township, PA), which incorporates modeling serial tomotherapy...
The purpose of this study is to evaluate 3D dose reconstruction pretreatment verification plans using multiple 2D planes acquired from the OCTAVIUS phantom and Seven29 detector array. Eight VMAT patient treatment different sites were delivered onto phantom. span a variety tumor site locations low high plan complexity. A specific quality assurance (QA) was created for each 8 patients in which array placed. Each four times by rotating 45° increments along its longitudinal axis. Novalis Tx with...
Purpose: To validate a 3D dose calculation methodology used by the Delta4™ phantom. Method and materials: Measurements were performed using TomoTherapy™ HiArt™ Varian 2300C/D™. A pinpoint PTW N31006 chamber with sensitive volume of 0.016cc was use for point measurements. The phantom (ScandiDos AB, Uppsala, Sweden) modified to accept ion chamber. Eight (n=8) quality assurance plans created in both planning systems. Plans covered range doses from 20% 160% (20% steps) prescribed Pinnacle 3 TPS....
Background . Lemierre syndrome (LS) is a rare complication of upper aerodigestive tract infections characterized by proximal and distal septic emboli, commonly including internal jugular vein (IJV) thrombosis. Diagnosis can be challenging, treatment delays result in increased patient morbidity mortality. We present case LS with extensive thrombosis multiple sites infection narrative review the literature. Case Presentation A 52‐year‐old Caucasian male was transferred to emergency department...
The purpose of this study was to commission a first-of-its-kind dual-layer micro multileaf collimator (mMLC) system by using Monte Carlo dose calculations. mMLC is attached on Varian 600C linac. Having lower and an upper layer MLC leaves, allows for field shaping in two orthogonal directions. commissioning the performed steps: without with treatment head modeled BEAMnrc (MC) code. scoring planes phase space files were specified below linac's secondary collimators (jaws) above mMLC. With...
We developed a dosimeter that measures biological damage following delivery of therapeutic beams in the form double-strand breaks (DSBs) to DNA. The contains DNA strands are labeled on one end with biotin and other fluorescein attached magnetic microbeads. Following irradiation, magnet is used separate broken from unbroken strands. Then, fluorescence utilized measure relative amount determine probability for DSB. long-term goal this research evaluate whether type biologically based holds any...
Purpose: To develop a software tool for processing the dose matrix from Hi Art Tomotherapy unit trial plan comparison and summation of doses between plans. Method Materials: A Visual C++ was developed in order to manipulate generated by planning station. The reads tomotherapy which is then exported into Pinnacle3 Two different trials can be compared dosimetrically or composite computed summing together multiple trials. script written out allows Pinnacle station setup appropriate parameters...
Purpose: The Monaco treatment planning system (TPS) uses a Monte‐Carlo algorithm based dose computation engine to model the photon beams of linear accelerator. aim is perform verification TPS beam modeling Elekta VersaHD linac with 6MV, 6MV FFF, 10 MV, 10MV 18MV and 160 multileaf collimators (MLC) projected width 5‐mm at isocenter. Methods: A series dosimetric tests were performed validate calculated including point measurement in water without heterogeneity 2‐dimensional distributions on...
Purpose: To model GTV's center of mass (COM) motion planes based on 4DCT lung data sets and establish possible correlation with the size and/or location as an aid in defining adequate GTV margins most prominent amplitude 3D space. Methods: For modeling COM throughout respiratory phases, eleven cancer patients were used least square fitting was applied. The generally involves either smoothening or apparent trend identification. Quadratic minimization, singular value decomposition, orthogonal...
Purpose: To calculate the daily fraction dose for a CBCT recalculation based on rigid registration and compare it to planned CT dose. Methods: For this study, 30 patients that were previously treated (10 SBRT lung, 10 prostate abdomen) considered. The images imported into Pinnacle treatment planning system from Mosaic. prescribing physician contoured regions of interest (ROI) each then was computed CBCT. Each distribution compared against plan. evaluation isodose line comparison Dose Volume...
Purpose: To estimate the dose distributions delivered to patient in each treatment fraction using deformable image registration (DIR) and assess radiobiological impact of inter‐fraction variations due deformation setup. Methods: The work is based on cone beam CT (CBCT) images plans two lung cancer patients. Both patients were treated with intensity modulated radiation therapy (IMRT) 66Gy 2Gy/fraction. exported from planning system (TPS) Velocity AI where DIR was performed same matrix used...
Purpose: Stereotactic radiosurgery (SRS) outcomes are related to the delivered dose target and surrounding tissue. We have commissioned a Monte Carlo based calculation algorithm recalculated planned using pencil beam engine. Methods: Twenty consecutive previously treated patients been selected for this study. All plans were generated iPlan treatment planning system (TPS) calculated algorithm. Each patient plan consisted of 1 3 targets dynamically conformal arcs or intensity modulated beams....
Purpose: A DNA double-strand break (DSB) dosimeter was developed to measure the biological effect of radiation. The goal here is refine fabrication method this reproducibly create a low coefficient variation (CoV) and reduce cost for dosimeter. Methods: Our consists 4 kilo-base pair strands (labeled on one end with biotin other fluorescein) attached streptavidin magnetic beads. final step suspend these beads in phosphate-buffered saline (PBS). amount PBS used relative volume both affect CoV...