Audrey M. Cordova

ORCID: 0009-0004-7444-7419
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About
Contact & Profiles
Research Areas
  • Single-cell and spatial transcriptomics
  • Renal Diseases and Glomerulopathies
  • Renal and related cancers
  • Genetic and Kidney Cyst Diseases
  • Complement system in diseases
  • Immune cells in cancer

University of Oklahoma Health Sciences Center
2023-2024

Kidney macrophages are comprised of both monocyte-derived and tissue resident populations; however, the heterogeneity kidney factors that regulate their poorly understood. Herein, we performed single cell RNA sequencing (scRNAseq), fate mapping, parabiosis to define cellular in healthy mice. Our data indicate mouse kidneys contain four major subsets monocytes two (KRM) including a population with enriched Ccr2 expression, suggesting monocyte origin. Surprisingly, mapping using newly...

10.3389/fimmu.2023.1082078 article EN cc-by Frontiers in Immunology 2023-05-15
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