A5041810167- Developmental Biology and Gene Regulation
- Hippo pathway signaling and YAP/TAZ
- Cellular Mechanics and Interactions
- Zebrafish Biomedical Research Applications
- Animal Behavior and Reproduction
- Genetics, Aging, and Longevity in Model Organisms
- Neurobiology and Insect Physiology Research
- Genetic diversity and population structure
Universidad Pablo de Olavide
2023-2024
Centro Andaluz de Biología del Desarrollo
2022-2023
Biological processes are intrinsically noisy, and yet, the result of development-like species-specific size shape organs-is usually remarkably precise. This precision suggests existence mechanisms feedback control that ensure deviations from a target minimized. Still, we have very limited understanding how these operate. Here, investigate problem organ using Drosophila eye. The adult eye depends on rates at which progenitor cells grow differentiate. We first find net growth rate results...
Abstract The assembly of the embryo’s primary axis is a fundamental landmark for establishment vertebrate body plan. Although morphogenetic movements directing cell convergence towards midline have been described extensively, little known on how gastrulating cells interpret mechanical cues. Yap proteins are well-known transcriptional mechanotransducers, yet their role in gastrulation remains elusive. Here we show that double knockout yap and its paralog yap1b medaka results an failure, due...
SUMMARY Biological processes are intrinsically noisy and yet, the result of development –like species-specific size shape organs– is usually remarkably precise. This precision suggests existence mechanisms feedback control that ensure deviations from a target minimized. Still, we have very limited understanding how these operate. Here, investigate problem organ using Drosophila eye. The adult eye depends on rates at which progenitor cells grow differentiate. We first find net growth rate...
ABSTRACT The condensation of the embryo primary axis is a fundamental landmark in establishment vertebrate body plan. Although complex morphogenetic movements directing cell convergence towards midline have been described extensively, little known on how gastrulating cells interpret mechanical cues. Yap proteins are among best characterized transcriptional mechanotransducers, yet their role gastrulation has remained elusive. Here we show that double knockout yap and its paralog yap1b medaka...