A5008414432- Toxoplasma gondii Research Studies
- Parasitic Infections and Diagnostics
- Parasite Biology and Host Interactions
- Helminth infection and control
- Animal Disease Management and Epidemiology
- Vector-borne infectious diseases
- Vector-Borne Animal Diseases
- Parasitic Diseases Research and Treatment
- Insect and Pesticide Research
- Viral Infections and Vectors
- Parasites and Host Interactions
- Insect Pest Control Strategies
- Coccidia and coccidiosis research
- Herpesvirus Infections and Treatments
- Parasitic infections in humans and animals
- Microbial infections and disease research
- Entomological Studies and Ecology
- Congenital Anomalies and Fetal Surgery
- Toxin Mechanisms and Immunotoxins
- T-cell and Retrovirus Studies
- Immune Response and Inflammation
- Mycobacterium research and diagnosis
- Ecology and biodiversity studies
- Viral gastroenteritis research and epidemiology
- Insects and Parasite Interactions
Département Santé Animale
2014-2022
Elanco (United States)
2021-2022
Novartis (Switzerland)
2008-2015
University of Bern
1998-2010
Institute of Parasitology
2005-2008
Institute of Virology of the Slovak Academy of Sciences
1997
The prevalences of Cryptosporidium parvum, rotavirus, bovine coronavirus (BCV), and enterotoxigenic Escherichia coli (E K99) were determined in diarrhoeic dairy calves aged one to 21 days on 71 farms western Switzerland during the winter 2005 2006. Faecal samples from 147 untreated suffering acute diarrhoea analysed by standardised diagnostic methods, immunoglobulin status each calf was evaluated. C BCV E k99 55.0 per cent, 58.7 7.8 cent 5.5 respectively. proportions herds positive for...
Two cats with Leishmania species infections were investigated. The first had been imported from Spain a non‐healing, ulcerated nodule on hindleg. presence of was detected by histopathology and PCR samples skin. lesion unresponsive to treatment allopurinol for three months but the cat treated successfully removing surgically. second lived in both Switzerland, history recurrent skin lesions its head neck. A diagnosis pemphigus foliaceus made basis histopathology, serology ( ELISA ) positive,...
Drug resistance has become a global phenomenon in gastrointestinal nematodes of sheep, particularly to macrocyclic lactones. New anthelmintics are urgently needed for both the control infections with multi-resistant areas where classical no longer effective, and prevention spread problem is not as severe. Recently, two new active ingredients became commercially available treatment nematode monepantel (Zolvix®) derquantel, latter used only formulated combination lactone, abamectin...
Resistance to synthetic pyrethroids (SP) in the cattle tick Rhipicephalus (Boophilus) microplus is widespread throughout its distribution area. Three single nucleotide substitutions identified Domains II and III of sodium channel gene R. (B.) are known be associated with target site pyrethroid resistance. We developed a multiplex PCR using allele-specific primers amplify wild type or mutated genotypes three mutations simultaneously. This assay was used screen samples originating from Brazil,...
Infestations with ticks have an important economic impact on the cattle industry worldwide and resistance to acaricides has become a widespread phenomenon. To optimize their treatment strategy, farmers need know if against which classes potential acaricide-resistance does occur. Bioassays are used assess level pattern of Rhipicephalus (Boophilus) microplus populations. The objective current study was susceptibility field populations originating from Argentina (8), South Africa (3), Australia...
The isoxazolines are a novel class of parasiticides that potent inhibitors γ-aminobutyric acid (GABA)-gated chloride channels (GABACls) and, to lesser extent, inhibitory glutamate-gated (GluCls). Lotilaner (Credelio™), representative this chemical class, is currently evaluated for its excellent ectoparasiticide properties.In study, we investigated the molecular mode action and pharmacology lotilaner. We report successful gene identification, cDNA cloning functional expression in Xenopus...
Neospora caninum is an important cause of infectious abortion and stillbirth in cattle world-wide. Infection common may frequently be passed from mother to calf (vertical transmission) with no signs disease. Based on our previous observation that N. caninum-infection can efficiently controlled toltrazuril-sulfone (ponazuril) experimentally infected mice, we addressed the question if efficacy could also obtained calves.The study included 19 calves represents initial explorative approach...
Intestinal cestodes are infecting millions of people and livestock worldwide, but treatment is mainly based on one drug: praziquantel. The identification new anti-cestodal compounds hampered by the lack suitable screening assays. It difficult, or even impossible, to evaluate drugs against adult in vitro due fact that these parasites cannot be cultured microwell plates, larval stages most cases represent different organisms terms size, morphology, metabolic requirements. We here present an...
Abstract Theileria annulata is a tick-transmitted protozoan parasite of cattle, which transforms cells macrophage (Mɸ) or B cell lineage. Bone marrow cells, bone cell-derived, and monocyte-derived Mɸ were infected with T. sporozoites, the resulting lines assessed for surface marker expression function. Transformed expressed histocompatibility complex (MHC) class-I II, CD44, CD45, myeloid DH598-surface markers CD14, CD11b, M-M7, TH57A, to lesser extent CD11a/CD18, CD11c, ACT(B),...