A5090307071- Bladder and Urothelial Cancer Treatments
- Advanced X-ray and CT Imaging
- Cardiac Imaging and Diagnostics
- Radiation Dose and Imaging
- RNA modifications and cancer
- Renal cell carcinoma treatment
- Hippo pathway signaling and YAP/TAZ
- Psychopathy, Forensic Psychiatry, Sexual Offending
- Pediatric Urology and Nephrology Studies
- Immune cells in cancer
- Lung Cancer Treatments and Mutations
- RNA regulation and disease
- Virus-based gene therapy research
- Cancer Immunotherapy and Biomarkers
- MRI in cancer diagnosis
- Hydrogen's biological and therapeutic effects
- Atherosclerosis and Cardiovascular Diseases
- Reproductive System and Pregnancy
- Crime Patterns and Interventions
- Kruppel-like factors research
- Cardiovascular Disease and Adiposity
- Adrenal and Paraganglionic Tumors
- Pain Management and Treatment
- Lung Cancer Research Studies
- Wnt/β-catenin signaling in development and cancer
China National Pharmaceutical Group Corporation (China)
2025
Shenzhen Institutes of Advanced Technology
2024
Chinese Academy of Sciences
2024
Affiliated Hospital of North Sichuan Medical College
2024
Obstetrics and Gynecology Hospital of Fudan University
2022
West China Medical Center of Sichuan University
2020
Neusoft (China)
2019
Sichuan University
2019
Harbin Medical University
2016
Second Affiliated Hospital of Harbin Medical University
2016
Trifolin exhibits anti-tumor activities; however, its effect on hypertension remains unknown. This study was performed to investigate trifolin's potential therapeutic effects and underlying mechanisms of action angiotensin II (Ang II)-induced in mice Ang stimulated A7R5 cells. Mice were randomly allocated into six groups: control, II, + (0.1 mg/kg), (1 (10 Valsartan mg/kg). The hypertensive mouse model constructed by infusing via a micro-osmotic pump (500 ng/kg/min), trifolin, valsartan, or...
Abstract Intracerebral hemorrhage (ICH) is a severe stroke subtype with high mortality and limited therapeutic options. The blood-brain barrier (BBB) breakdown post-ICH exacerbates secondary brain injury, highlighting the need for targeted therapies to preserve BBB integrity. We aim investigate role of Sphk1/S1P pathway in following ICH evaluate potential Sphk1 inhibition mitigating this breakdown. Using combination human patient samples, mouse models ICH, vitro cellular assays, we assessed...
The purpose of this study was to evaluate the impact artificial intelligence (AI)-based noise reduction algorithm on aorta computed tomography angiography (CTA) image quality (IQ) at 80 kVp tube voltage and 40 mL contrast medium (CM).After obtaining institutional review board approval 8 written informed consents, 60 patients (35 men, 25 women; age range: 18 85 y) referred for CTA examination were assigned 2 groups random. Group A underwent an protocol with CM (320 mg I/mL). reconstructed...
Abstract Hormone therapy resistance and the ensuing aggressive progression of tumors present a significant clinical challenge. However, mechanisms underlying induction tumor malignancy by hormone inhibition remain poorly understood. Here we show that Drosophila malignant epithelial exhibit comparable decrease in ecdysone signaling, primary steroid pathway . Furthermore, find ectopic expression nuclear receptor E75 partially mimics signaling inhibition, specifically promoting transformation...
The aim of the study was to evaluate image quality coronary computed tomography (CT) angiography (CCTA) in obese patients by using deep learning reconstruction (DLIR) comparison with adaptive statistical iterative Veo (ASiR-V).We prospectively evaluated 60 (body mass index [BMI] ≥ 30 kg/m2) who underwent CT a single center. All scans were performed GE Revolution 256-row at 120 kV (group A; 20 men, 10 women; mean age = 54.3 years; BMI 33.4 or 100 B; 18 men; 12 56.8 32.9 kg/m2). Images group A...
Embryo implantation, a critical step during the mammalian reproductive process, requires normal developing blastocysts and receptive endometrium. Endometriosis, common pathologically benign gynecological condition, is associated with decreased fertility reduced endometrial receptivity. The oncoprotein, Gankyrin, has been endometriosis cancer. Here, we examined role of Gankyrin process embryo implantation found that expression levels were significantly increased mid-secretory phase, but...
Objective: To evaluate the diagnostic efficacy of CT in differentiating adrenal adenomas from malignant tumors. Methods: 124 patients with 147 and tumors were analyzed. Tumor size, margin, internal structure relation tumor to gland investigated CT. Both precontrast postcontrast attenuation values measured enhanced degree was calculated respectively. pixel mapping done 20 patients. Results analyzed by using ROC curve. Results: The area under curve for (0.91±0.05) significantly larger than...
A 77-year-old woman was presented to our department after suffering from 20 days of dizziness and fatigue.She had a history hypertension for 40 years type 2 diabetes mellitus ten years.On examination, blood pressure 172/67 mm Hg (right upper extremity), 170/70 (left 85/57 lower extremity) 98/60 extremity).Computed tomography angiography aorta showed stenosis left subclavian artery (Fig. 1A) severe descending aortic (Figs.1B,C), with extensive collateralisation between arteria iliaca...
Objective To explore the characteristics of individuals with mental disorders suspected road traffic offences and to find their differences from normal offenders, in order regulate disorder patients' driving activities prevent offences. Methods One hundred twenty-three cases forensic psychiatry testimony between 2014 2019 West China Forensic Center Sichuan Province were collected. Fisher exact probability test was used compare offenders without terms demographic characteristics,...