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Drake J. Thompson

ORCID: 0009-0004-8143-0842
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About
Contact & Profiles
A5101469978
Research Areas
  • Molecular Biology Techniques and Applications
  • Cancer Genomics and Diagnostics
  • Single-cell and spatial transcriptomics

National Institute on Drug Abuse
 2023

 MultipleXed Population Selection and Enrichment single nucleus RNA sequencing (XPoSE-seq) enables sample identity retention during transcriptional profiling of rare populations
OPENALEX - Publications 
Katherine E. Savell Rajtarun Madangopal Padmashri Saravanan Ryan G. Palaganas Kareem D. Woods and 12 more Drake J. Thompson Olivia R. Drake Megan B. Brenner Sophia J. Weber Elise Van Leer J.H. Howard Choi Toni L. Martin Jody Martin Mia Steinberg James W. Austin Chloé I. Charendoff Bruce T. Hope

Abstract Single nucleus RNA-sequencing is critical in deciphering tissue heterogeneity and identifying rare populations. However, current high throughput techniques are not optimized for target populations require tradeoffs design due to feasibility. We provide a novel snRNA pipeline, Muliple X ed Po pulation S election E nrichment snRNA-sequencing ( XPoSE-seq ), enable targeted snRNA-seq experiments in-depth transcriptomic characterization of while retaining individual sample identity.

10.1101/2023.09.27.559834 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2023-09-29
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