- Organ Transplantation Techniques and Outcomes
- Transplantation: Methods and Outcomes
- Xenotransplantation and immune response
- Pediatric Hepatobiliary Diseases and Treatments
- Hepatitis C virus research
- Gallbladder and Bile Duct Disorders
- Liver Disease Diagnosis and Treatment
- Clinical Nutrition and Gastroenterology
- Pluripotent Stem Cells Research
- Drug Transport and Resistance Mechanisms
- Receptor Mechanisms and Signaling
- RNA Research and Splicing
- Developmental Biology and Gene Regulation
- Frailty in Older Adults
- CRISPR and Genetic Engineering
- Peroxisome Proliferator-Activated Receptors
- Gastroesophageal reflux and treatments
- Microtubule and mitosis dynamics
- Cancer-related molecular mechanisms research
- Immunodeficiency and Autoimmune Disorders
- Diet and metabolism studies
- Tissue Engineering and Regenerative Medicine
- Influenza Virus Research Studies
- Hematological disorders and diagnostics
- Immune Response and Inflammation
Shanghai East Hospital
2024
First Affiliated Hospital of Soochow University
2024
State Key Laboratory of Cardiovascular Disease
2024
Tongji University
2009-2024
Shuguang Hospital
2024
Shanghai University of Traditional Chinese Medicine
2024
Soochow University
2024
Jinhua Central Hospital
2017
University of Chicago
2007
Toronto General Hospital
1998
Male Sprague-Dawley rats were randomly divided into five groups in which group 1 received a sham operation (controls), 2-5 underwent common bile duct ligation and transection 14 days before the experiments. Two prior to studies, animals 2 saline orally, while 3–5 an oral administration of either cholic acid, deoxycholic acid or whole bile. Specimens taken for bacterial culture, blood was collected endotoxin assay. The rate positive cultures from mesenteric lymph nodes jaundiced salinetreated...
ABSTRACT The strain-specific spectrum of liver disease following murine hepatitis virus type 3 (MHV-3) infection is dependent on inflammatory mediators released by macrophages. Production nitric oxide (NO) macrophages has been implicated in resistance to a number viruses, including ectromelia virus, vaccinia and herpes simplex 1. This study was undertaken define the role NO MHV-3 infection. Gamma interferon-induced production inhibited growth macrophage cell line (RAW 264.7). Viral...
Anti-graft antibodies are often associated with graft rejection. Under special conditions, grafts continue to function normally even in the presence of anti-graft and complement. This condition is termed accommodation. We developed a xenograft accommodation model which baby Lewis rat hearts transplanted into Rag/GT-deficient mice, induced by repeated i.v. injections low-dose anti-α-Gal IgG<sub>1</sub>. The accommodated survived bolus dose IgG<sub>1</sub>, while freshly second were rejected....
Abstract The recovery of reticuloendothelial system (RES) function following decompression obstructive jaundice was studied using a rat model with bile duct ligation and side-to-side choledochoduodenostomy. Histopathological changes in the liver were still present 5 weeks after relief jaundice, while results tests had returned to normal. RES evaluated by blood clearance organ uptake radiolabelled Escherichia coli corrected phagocytic index gradually normal biliary decompression. severely...
ObjectivesTo investigate the effectiveness of 10-day bismuth-containing quadruple (B-quadruple) treatment as first-line therapy in patients with Helicobacter pylori–related chronic gastritis.MethodsA randomized controlled trial was conducted from October 2011 to December 2013 Zhejiang, China, including H. gastritis who were randomly provided either omeprazole-based triple (OM-triple; omeprazole 20 mg twice daily, clarithromycin 500 daily and amoxicillin 1 g daily) or B-quadruple (OM-triple +...
Chronic obstructive pulmonary disease (COPD) has become one of the major death-related causes. heart (CPHD) is an adverse complication COPD causing poor prognosis patients. This study evaluated role lncRNA XIST in and CPHD aiming to identify a potential biomarker for screening prediction COPD.
Rats with 2 weeks of biliary obstruction, and without 1 week concomitant decompression relieving the jaundice, were treated physiologic saline, free muramyl dipeptide (MDP), placebo liposomes, or liposome-encapsulated MDP. Reticuloendothelial system (RES) function was evaluated by blood clearance intravenously injected 125I-labelled Escherichia coli. The corrected phagocytic index (α) after returned to normal levels in animals MDP whereas RES impaired (P < 0.05) all other jaundiced...
Abstract Kupffer cells are important for host defence against both foreign invaders and neoplasia. Several studies have demonstrated that ischaemia reperfusion activates cells. The effect of hepatic arterial on cell function was assessed using blood clearance organ uptake radiolabelled Escherichia coli. Transient 1 h did not alter in comparison with sham operation. However, prolonging 2 stimulated function; the phagocytic index liver E. coli increased significantly (P &lt; 0.01)....
Cell fate determination and transition are of paramount importance in biology medicine. Naive pluripotency could be achieved by reprogramming differentiated cells. However, the mechanism is less clear. Osmolarity an essential physical factor that acts on living cells, especially for pluripotent but its significance cell remains unexplored. To investigate role osmolarity underlying mechanism. Flow cytometry, quantitative real-time PCR, teratoma chimeric mice assays were performed to assess...