A5101919461- Pharmaceutical Practices and Patient Outcomes
- Pharmacovigilance and Adverse Drug Reactions
- Schizophrenia research and treatment
- SARS-CoV-2 and COVID-19 Research
- Health Systems, Economic Evaluations, Quality of Life
- Vaccine Coverage and Hesitancy
- Heparin-Induced Thrombocytopenia and Thrombosis
- Atrial Fibrillation Management and Outcomes
- Simulation-Based Education in Healthcare
- Protease and Inhibitor Mechanisms
- Per- and polyfluoroalkyl substances research
- Clinical Reasoning and Diagnostic Skills
- Interprofessional Education and Collaboration
- Proteoglycans and glycosaminoglycans research
- Platelet Disorders and Treatments
- Patient Safety and Medication Errors
- Innovations in Medical Education
- Influenza Virus Research Studies
- Clinical practice guidelines implementation
- Blood Coagulation and Thrombosis Mechanisms
- Venomous Animal Envenomation and Studies
- Virus-based gene therapy research
University of Copenhagen
2020-2024
Loyola University Medical Center
1981
In 2021, thrombosis with thrombocytopenia syndrome (TTS) was confirmed by the European Medicines Agency (EMA) as a rare side effect of COVID-19 adenovirus vector vaccines Vaxzevria® and Jcovden®. This study aimed to describe public's knowledge TTS how it affected willingness be vaccinated other in six countries. From June October 2022, multi-country cross-sectional online survey conducted Denmark, Greece, Latvia, Netherlands, Portugal, Slovenia. The minimum target participants recruited...
Risk minimisation measures (RMMs) aim to ensure safe use of medicines, but their implementation in clinical practice is complicated by the diversity stakeholders whose decision making they seek inform. Clinical guidelines (CPGs) are considered integral making. To determine extent which RMMs included relevant CPGs and describe factors that RMM inclusion. A multi-case study design using quantitative document analysis combined with qualitative interviews informants from organisations issue...
Background: Drug-related problems (DRPs) affect many patients. Many activities in general practice, hospitals, and community pharmacies have been initiated to tackle DRPs. However, recent studies exploring what DRP patients are still facing their daily lives scarce. Methods: Danish pharmacy staff registered DRPs prescription encounters understand experiencing life. They noted short descriptions of happened the encounter that qualified incident as a DRP. The were subjected an inductive...
Pharmacists need more insight into patients' perspectives on medicine to target their counseling and improve patient outcomes. Patient simulation exercises, where pharmacy students are asked consume medicine-like products, have been shown foster such understandings, although the specifics of how this occurs, in particularly, turn first-person toward generalizations about real lives with medicines, not well documented. The aim was identify central aspects learning process by introducing...
Abstract Objectives The role of Danish clinical practice guidelines in making the health care sector aware and act accordance with medicines safety information from regulators, has not been extensively studied. objectives this study were 1) to describe extent which additional risk minimization measures is included 2) explore guideline developers’ attitudes towards including guidelines. Methods focused on five therapeutic areas combined quantitative document analyses 91 qualitative...
Ultra low molecular weight saccharide fragments (ULMFs) have been obtained from porcine mucosal heparin (PMH) by extraction (e-ULMF) and bacterial heparinase depolymerization (h-ULMF-8) processes. Both showed a strong anti Xa activity (>2000 u/mg units, Yin Wessler, J. Lab. Clin. Med. 81, 298, 1973) possess relatively weak potencies in the US Pharmacoepial (<40 USP u/mg) other conventional coagulant assays (activated non activated partial thromboplastin time, thrombin time whole blood...
Since its introduction the Wessler stasis rabbit model (Wessler, et al. J. Appl. Physiol. 14:(6), 943, 1959) has been widely used in evaluation of thrombogenic properties prothrombin complex concentrates (activated and non-activated) antithrombotic effects various drugs. In order to study actions low molecular weight fractions oligosaccharide fragments we a modified (rabbit) with stimuli which produced marked increase circulating factor Xa levels. Male New Zealand rabbits ranging from 23 kg...
Background: Immunotoxicity has been selected as the critical effect of early-life exposures to perfluorinated alkylate substances (PFASs) in a 2020 draft opinion by European Food Safety Authority. However, uncertainty prevails regard most vulnerable age at exposure.Methods: A birth cohort 490 children was recruited Faroe Islands 2007-2009 and followed up with blood samples ages 18 months, 5 9 years. PFAS concentrations were quantified umbilical cord collected postnatal examinations....