A5022365660- Stress Responses and Cortisol
- Acute Myeloid Leukemia Research
- Animal Vocal Communication and Behavior
- Tryptophan and brain disorders
- Primate Behavior and Ecology
- Neurotransmitter Receptor Influence on Behavior
- Neuroendocrine regulation and behavior
- Marine animal studies overview
- Adrenal Hormones and Disorders
- Hematological disorders and diagnostics
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Eosinophilic Disorders and Syndromes
- Immune Cell Function and Interaction
- Mast cells and histamine
- Animal Behavior and Reproduction
- Clinical Nutrition and Gastroenterology
- Peptidase Inhibition and Analysis
- Tuberculosis Research and Epidemiology
- Adipose Tissue and Metabolism
- Neutropenia and Cancer Infections
- Acute Lymphoblastic Leukemia research
- Digestive system and related health
- Alcohol Consumption and Health Effects
- Protein Degradation and Inhibitors
- Retinoids in leukemia and cellular processes
Icahn School of Medicine at Mount Sinai
2023-2024
Tisch Cancer Institute
2024
Mount Sinai Hospital
2023
National Institutes of Health
2004-2012
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2012
National Institute on Alcohol Abuse and Alcoholism
2003-2004
University of Memphis
1999-2003
University of Göttingen
1939-1987
Background: Decreased sensitivity to alcohol has been demonstrated be a predictor of alcoholism in humans, and variation the gene‐linked polymorphic region serotonin transporter (5‐HTTLPR) is associated with response motor‐impairing effects alcohol. In nonhuman primate model excessive intake, we have shown that decreased turnover both lower initial higher prospective consumption using rhesus macaques. addition, macaques separated from their mothers reared peer‐only groups are more likely...
Although relatively rare, acute myeloid leukemia (AML) is the most common type of in adults. AML associated with poor 5-year overall survival and prompt treatment critical. Classifying based on World Health Organization criteria important for determining prognosis applying a risk-adapted approach. Throughout therapy, patients require comprehensive supportive care measures blood product transfusions, antimicrobial treatment, frequent monitoring chemotherapy-related complications. This article...
<h3>Context</h3> Both highly stress-reactive and novelty-seeking individuals are susceptible to alcohol use disorders. Variation in stress reactivity, exploration, response novelty have been attributed differences corticotropin-releasing hormone (CRH) system function. As such,<i>CRH</i>gene variation may influence risk for dependence. <h3>Objective</h3> To determine whether<i>CRH</i>variation influences relevant intermediate phenotypes, behavior, consumption rhesus macaques. <h3>Design</h3>...
We report the first case of pacritinib-withdrawal syndrome with in vitro elucidation underlying mechanisms.
Background: Studies in rodents demonstrate sex differences neuroendocrine stress axis activity after treatment with alcohol. In abstinent alcoholics, atypical depressives, and individuals posttraumatic disorder, limbic‐hypothalamic‐pituitary‐adrenal (LHPA)‐axis is often blunted; among females these patient populations, however, resistance to glucocorticoid feedback increased pituitary reactivity observed. Early parental loss a major life stressor risk factor for both affective disturbances...
AbstractWe evaluated outcomes of AML patients with central nervous system (CNS) involvement at two academic institutions. Fifty-two adult were identified. Neurologic symptoms reported in 69% patients, headache the most common (33%). 84% (n = 42) cleared their cerebrospinal fluid (CSF), a median number one dose intrathecal (IT) chemotherapy. Of these 21% 9) had CSF relapse, 67% 6) those experiencing relapse also having concurrent bone marrow relapse. 36 baseline neurologic symptoms,...
Zusammenfassung Eine beträchtliche Steigerung des Blutzuckers beim Huhn wurde nach der Zufuhr von Glukose und Galaktose gefunden; Lävu‐losegaben war sie selten dann sehr gering, desgleichen Rohrzucker. Der Milchzucker rief nie eine Blutzuckererhöhung hervor. Aus dem wird Glykogen entweder gar nicht oder nur in ganz unbedeutender Menge gebildet. Bis über 50 % aufgenommenen Milchzuckers unverändert ausgeschieden. ausgeschiedene verfällt einer gesteigerten Darmgärung unter vorwiegender...
Abstract A relationship between alcohol intake and aggressive behavior has been demonstrated in both associational laboratory studies. Among the factors that contribute to aggression during intoxication are a history of violence level alcohol‐induced stimulation. In humans, excessive alcoholism predicted by decreased sensitivity, or low response (LOR), alcohol. addition, behavior, LOR, have attributed CNS serotonergic dysfunction. Given they related diminished serotonin, this study we wanted...
Garnett’s greater bushbaby infants vocalize in apparent response to their mother’s contact calls. However, it remains unclear whether specific vocal or behavioral patterns by a mother elicit this response. We video-recorded the behaviors and vocalizations of 4 individual mother-infant groups (mother with twins), analyzed via spectrography documented mothers infants. Initial analyses all revealed that short growls growl bouts (or chains), but not long growls, emitted mothers, were followed...