A5010309184- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Acute Myeloid Leukemia Research
- Neutropenia and Cancer Infections
- Chronic Myeloid Leukemia Treatments
- Colorectal and Anal Carcinomas
- Venous Thromboembolism Diagnosis and Management
- CAR-T cell therapy research
- Palliative Care and End-of-Life Issues
- Hemoglobinopathies and Related Disorders
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer survivorship and care
- Liver Disease and Transplantation
- Platelet Disorders and Treatments
- Cancer Immunotherapy and Biomarkers
- Economic and Financial Impacts of Cancer
- Pharmacological Effects and Toxicity Studies
- Otolaryngology and Infectious Diseases
- Hidradenitis Suppurativa and Treatments
- Wnt/β-catenin signaling in development and cancer
- Cerebral Venous Sinus Thrombosis
- Acute Lymphoblastic Leukemia research
- Chemotherapy-induced cardiotoxicity and mitigation
- Inflammatory Myopathies and Dermatomyositis
- Chronic Lymphocytic Leukemia Research
The Ohio State University Wexner Medical Center
2024
Icahn School of Medicine at Mount Sinai
2020-2024
The Ohio State University
2024
St. Luke's-Roosevelt Hospital Center
2019
Nano-liposomal irinotecan (nal-IRI) plus 5-fluorouracil/leucovorin (5-FU/LV) is the regimen of choice in 2nd line setting for advanced pancreatic adenocarcinoma (PAC). However, real-world data limited. Our objectives were to elicit real-word effectiveness and safety this combination as an therapy cancer patients analyze impact prior lines on survival outcomes with regimen.We conducted a retrospective cohort study 58 locally unresectable or metastatic PAC, who treated at least one dose...
We report the first case of pacritinib-withdrawal syndrome with in vitro elucidation underlying mechanisms.
Abstract Factor XI (FXI) deficiency is an autosomal inherited, milder bleeding disorder that may predispose to a potential risk of life-threatening during childbirth or surgery. Unfortunately, data regarding obstetric and perioperative management this condition are scarce, with limited cases reviewed in the last decade. Therefore, present study aimed expand database identify factors associated increased risk. We performed retrospective chart review patients FXI who underwent other surgical...
Objective: To evaluate the effectiveness of noradrenaline for treatment hepatorenal syndrome (HRS). Background: HRS represents development renal failure in cirrhotic patients. The standard is terlipressin, which, as opposed to noradrenaline, more expensive and less accessible most tertiary care centers. Patients methods: Thirty consecutive patients with type 1 received (1–4.0 mg/hour) albumin 14 days. parameters recorded were: serum creatinine levels, clearance, mean arterial pressure (MAP),...
Although multiple genetic events are thought to play a role in promoting progression of the myeloproliferative neoplasms (MPN), individual that associated with development more aggressive disease phenotypes remain poorly defined. Here, we report novel genomic deletions at chromosome 12q14.3, as detected by high-resolution array comparative hybridization plus single nucleotide polymorphisms platform, occur 11% MPN patients myelofibrosis (MF) and MPN-accelerated/blast phase (AP/BP) but was not...
Irritable bowel syndrome is classified as a functional gastrointestinal disorder with the primary symptom of abdominal pain in conjunction bloating and movement disorder. It affects up to 15% world's population. Among its subtypes, most common diarrhoea predominant. However, current treatment options for diarrhoea-predominant irritable have had not very promising results; most, such antispasmodics, only provide partial symptomatic relief. Treatment antidepressants alosetron (a 5HT3...
Gastrointestinal cancers have a strong association with splanchnic vein thrombosis (SVT), yet the hospitalization data is unknown.We analyzed around 78 million discharges from 2007-2017 Nationwide Inpatient Sample an inclusion criterion of adult patients admitted for portal or hepatic as primary diagnosis gastrointestinal hepatobiliary malignancy secondary diagnosis. The outcomes were in-hospital mortality, complication rates, and resource utilization. Odds ratios (OR) means adjusted...
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Stroke in a migraine with aura has been documented several cases, even deserving the merit of classification as complicated migraine. Herein, we present rare case migrainous infarct without aura. The diagnosis was challenging due to lack risk factors. patient unique not having any other comorbidities.The is 21-year-old female presenting right-sided hemiplegia and facial drooping. She had an index presentation throbbing headaches for past 2 years, typical but preceded by symptoms. However,...