Joyce Kwan

ORCID: 0009-0005-0254-4751
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About
Contact & Profiles
Research Areas
  • Cold Atom Physics and Bose-Einstein Condensates
  • Advanced Thermodynamics and Statistical Mechanics
  • Quantum Information and Cryptography
  • Quantum and electron transport phenomena
  • Quantum many-body systems
  • CAR-T cell therapy research
  • Cancer Immunotherapy and Biomarkers
  • Theoretical and Computational Physics
  • Statistical Mechanics and Entropy
  • Physics of Superconductivity and Magnetism
  • Protein Structure and Dynamics
  • Nicotinic Acetylcholine Receptors Study
  • Computational Fluid Dynamics and Aerodynamics
  • Monoclonal and Polyclonal Antibodies Research
  • Cancer Research and Treatments
  • Quantum Computing Algorithms and Architecture
  • Ionosphere and magnetosphere dynamics
  • Immunotherapy and Immune Responses
  • Surface and Thin Film Phenomena
  • Spectroscopy and Laser Applications
  • Creativity in Education and Neuroscience
  • Magnetic confinement fusion research
  • Chemical Synthesis and Analysis
  • Mass Spectrometry Techniques and Applications
  • Forecasting Techniques and Applications

Harvard University
2020-2024

Low-dimensional quantum systems can host anyons, particles with exchange statistics that are neither bosonic nor fermionic. However, the physics of anyons in one dimension remains largely unexplored. In this work, we realize Abelian arbitrary using ultracold atoms an optical lattice, where engineer statistical phase through a density-dependent Peierls phase. We explore dynamical behavior two undergoing walks and observe anyonic Hanbury Brown–Twiss effect as well formation bound states...

10.1126/science.adi3252 article EN Science 2024-11-28

Antibody-Drug Conjugates (ADCs) are targeted cancer therapies delivering cytotoxic agents selectively to cells. Despite clinical success across various malignancies, resistance ADC therapy limits long-term efficacy. A key mechanism is inducing immunogenic cell death (ICD), releasing damage-associated molecular patterns (DAMPs) and tumor antigens stimulate an immune response. This provides a rationale for combining ADCs with immunotherapies overcome improve survival rates.AWT020 novel fusion...

10.1158/1538-7445.am2025-4774 article EN Cancer Research 2025-04-21

Low-dimensional quantum systems can host anyons, particles with exchange statistics that are neither bosonic nor fermionic. Despite indications of a wealth exotic phenomena, the physics anyons in one dimension (1D) remains largely unexplored. Here, we realize Abelian 1D arbitrary using ultracold atoms an optical lattice, where engineer statistical phase via density-dependent Peierls phase. We explore dynamical behavior two undergoing walks, and observe anyonic Hanbury Brown-Twiss effect, as...

10.48550/arxiv.2306.01737 preprint EN other-oa arXiv (Cornell University) 2023-01-01

Strongly correlated systems can exhibit surprising phenomena when brought in a state far from equilibrium. A spectacular example are quantum avalanches, that have been predicted to run through many-body--localized system and delocalize it. Quantum avalanches occur the is locally coupled small thermal inclusion acts as bath. Here we realize an interface between of variable size, study its dynamics. We find evidence for accelerated transport into localized region, signature avalanche. By...

10.48550/arxiv.2012.15270 preprint EN cc-by arXiv (Cornell University) 2020-01-01

New generations of ultracold-atom experiments are continually raising the demand for efficient solutions to optimal control problems. Here, we apply Bayesian optimization improve a state-preparation protocol recently implemented in an system realize two-particle fractional quantum Hall state. Compared manual ramp design, demonstrate superior performance our approach numerical simulation – resulting that is 10x faster at same fidelity, even when taking into account experimentally realistic...

10.22331/q-2024-06-27-1388 article EN cc-by Quantum 2024-06-27

We report on adiabatic state preparation in the one-dimensional quantum Ising model using ultracold bosons a tilted optical lattice. prepare many-body ground states of controllable system sizes and observe enhanced fluctuations around transition between paramagnetic antiferromagnetic states, marking precursor critical behavior. Furthermore, we find evidence for superpositions domain walls study their effect by measuring populations each spin configuration across transition. These results...

10.48550/arxiv.2404.07481 preprint EN arXiv (Cornell University) 2024-04-11

Understanding the mechanism of high-temperature superconductivity is among most important problems in physics, for which quantum simulation can provide new insights. However, it remains challenging to characterize existing cold-atom platforms. Here, we introduce a protocol measuring broad class observables fermionic gas microscopes, including long-range superconducting pairing correlations (after repulsive-to-attractive mapping). The only requires global controls followed by site-resolved...

10.48550/arxiv.2412.13186 preprint EN arXiv (Cornell University) 2024-12-17

Strongly interacting topological matter exhibits fundamentally new phenomena with potential applications in quantum information technology. Emblematic instances are fractional Hall states, where the interplay of magnetic fields and strong interactions gives rise to fractionally charged quasi-particles, long-ranged entanglement, anyonic exchange statistics. Progress engineering synthetic has raised hope create these exotic states controlled systems. However, except for a recent Laughlin state...

10.48550/arxiv.2210.10919 preprint EN cc-by arXiv (Cornell University) 2022-01-01

Abstract The tumor microenvironment (TME) has been identified as a significant obstacle to the success of immunotherapy, including anti-PD-1 therapy. TME comprises several factors that limit response rate immunosuppressive cells such regulatory T (Tregs), which directly or indirectly interact with effector and undermine recognition, activation, proliferation, survival cells, thereby promoting growth. To overcome suppressive TME, we designed AWT030, first-in-class bi-functional IL-21 fusion...

10.1158/1538-7445.am2023-lb029 article EN Cancer Research 2023-04-14

The study of fractional Chern insulators and their exotic anyonic excitations poses a major challenge in current experimental theoretical research. Quantum simulators, particular ultracold atoms optical lattices, provide promising platform to realize, manipulate, understand such systems with high degree controllability. Recently, an atomic $\nu=1/2$ Laughlin state has been realized experimentally for small system two particles on 4 by sites. next concerns the preparation states extended...

10.48550/arxiv.2309.17402 preprint EN other-oa arXiv (Cornell University) 2023-01-01

New generations of ultracold-atom experiments are continually raising the demand for efficient solutions to optimal control problems. Here, we apply Bayesian optimization improve a state-preparation protocol recently implemented in an system realize two-particle fractional quantum Hall state. Compared manual ramp design, demonstrate superior performance our approach numerical simulation - resulting that is 10x faster at same fidelity, even when taking into account experimentally realistic...

10.48550/arxiv.2312.09253 preprint EN other-oa arXiv (Cornell University) 2023-01-01

The 53rd Annual Meeting of the APS Division Atomic, Molecular and Optical Physics will take place from May 30 – June 3, 2022 in Orlando, Fl, USA. <a href="https://morressier.zoom.us/j/89880865272?pwd=SWxTRGhra1ZOSDBrSkhVZDBzVDR6UT09/">Virtual Presenter Help Desk</a>

10.26226/m.6275705e66d5dcf63a3116d6 preprint EN 2022-05-25
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