A5101987475- Plant Genetic and Mutation Studies
- Plant and Fungal Interactions Research
- Magnetic and Electromagnetic Effects
- Silicon Effects in Agriculture
- Genomics and Phylogenetic Studies
- Nuts composition and effects
- Plant Pathogens and Fungal Diseases
- Microbial Metabolites in Food Biotechnology
- Plant Gene Expression Analysis
- Horticultural and Viticultural Research
- Genetic diversity and population structure
- Acupuncture Treatment Research Studies
- Cancer Immunotherapy and Biomarkers
- CAR-T cell therapy research
- Lung Cancer Diagnosis and Treatment
- Food Quality and Safety Studies
- Wnt/β-catenin signaling in development and cancer
- Natural product bioactivities and synthesis
- Rock Mechanics and Modeling
- Food composition and properties
- Infectious Diseases and Tuberculosis
- Pleural and Pulmonary Diseases
- Pain Mechanisms and Treatments
- Breast Lesions and Carcinomas
- Breast Cancer Treatment Studies
Sir Run Run Shaw Hospital
2025
Zhejiang University
2025
Jiangnan University
2024
Shanghai Institute of Hematology
2022-2023
Ruijin Hospital
2022-2023
Shanghai Jiao Tong University
2022-2023
Guiyang University
2022-2023
Beijing Jishuitan Hospital
2022
Peking University
2022
Yulin Normal University
2022
The transcription factor FoxN1 is essential for differentiation of thymic epithelial cell (TEC) progenitors during organogenesis. However, limited information available on the postnatal contribution to maintenance. To address this question, we generated a loxP-floxed (fx) mouse with three different promoter-driven inducible CreER(T) transgenes. Postnatal ubiquitous deletion caused dramatic atrophy in 5 days and more severe deterioration medullary TECs (mTECs) than cortical (cTECs). Induction...
Summary It has been speculated that aging lymphohematopoietic progenitor cells (LPC) including hematopoietic stem (HSC) and early T‐cell progenitors (ETP) have intrinsic defects trigger age‐related thymic involution. However, using a different approach, we suggest is not the case. We provided young microenvironment to aged mice by transplanting fetal thymus into kidney capsule of animals, demonstrated old mouse‐derived LPCs could re‐establish normal lymphopoiesis all thymocyte...
To explore the effect of multi-disciplinary cooperative mobile device-assisted drug education on satisfaction inpatients education. Mobile nursing vehicle, IPAD, and phone were used to scan QR code play propaganda videos distribute materials. Doctors, nurses pharmacists cooperated complete for inpatients. The was collected through a third-party survey. Before implementation, four satisfactions communicating about drug, understanding purpose informing role side 83.9%, 80.4%, 83.8%...
To investigate the release profile of met-enkephalin, β -endorphin, and dynorphin-A in ruminants’ CNS, goats were stimulated by electroacupuncture 0, 2, 40, 60, 80, or 100 Hz for 30 min. The pain threshold was measured using potassium iontophoresis. peptide levels determined with SABC immunohistochemisty. results showed that 60 increased 91%; its increasing rate higher (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...
Ophthalmic manifestations have recently been observed in acute and post-acute complications of COVID-19 caused by SARS-CoV-2 infection. Our precious study has shown that host RNA editing is linked to viral infection, yet ocular adenosine inosine (A-to-I) during infection remains uninvestigated COVID-19. Herein we used an epitranscriptomic pipeline analyze 37 samples investigate A-to-I associated with five tissue types including the conjunctiva, limbus, cornea, sclera, retinal organoids....
Abstract Alpha-B crystallin (CRYAB), as a small heat shock protein, has been found to be highly expressed in various human cancers and significantly associated with the unfavorable prognosis of these tumor. Nevertheless, clinical significance CRYAB gastric cancer (GC) angiogenesis remains elucidated. In this study, we evaluated expression CD34 GC tissues corresponding normal specimens explore whether high level is related poor GC. were detected by immunohistochemical (IHC) technique....
A lightweight foam phosphogypsum material (LFPM) was prepared by multi-factor orthogonal and optimization experiments. The effects of foam, quicklime, silica fume cement on the mechanical physical properties this LFPM were studied. experimental results showed that content exhibited most significant effect strength material, obvious influence softening coefficient. comprehensive index analysis indicated with 8% 3.5% 3% 15% selected as optimal proportion. 28 d compressive flexural 3.15 0.97...
Coryloideae is a subfamily in the family Betulaceae consisting of four extant genera: Carpinus, Corylus, Ostrya, and Ostryopsis. We sequenced plastomes six species Corylus one Ostryopsis for comparative phylogenetic analyses. The are 159–160 kb long possess typical quadripartite cp architecture. show moderate divergence conserved arrangement. Five mutational hotspots were identified by comparing seven Coryloideae: trnG-atpA, trnF-ndhJ, accD-psaI, ndhF-ccsA, ycf1. assembled most complete...
In order to investigate the dynamic processes of mRNA levels proenkephalin, proopiomelanocortin, prodynorphin, and opioid receptors (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mrow><mml:mi>δ</mml:mi></mml:mrow></mml:math>-,<mml:math id="M2"><mml:mrow><mml:mi>μ</mml:mi></mml:mrow></mml:math>-, and<mml:math id="M3"><mml:mrow><mml:mi>κ</mml:mi></mml:mrow></mml:math>-receptor) induced by electroacupuncture (EA) in central nerve system, goats were stimulated EA 60 Hz...
There are few reports regarding video-assisted thoracoscopic therapeutic resection for medically failed pulmonary tuberculosis (TB). We reviewed our surgical results of surgery (VATS) TB with medical failure, and its correlation image characteristics on chest computed tomography (CT) scan. Between January 2007 December 2012, among the 203 patients who had TB, records 89 undergoing were reviewed. Clinical information CT scan investigated analyzed. Forty-six successful VATS significantly lower...
The thermoresponsive Zinc TetraPhenylPorphyrin photosensitizer/Dextran poly (N-isopropylacrylamide) graft copolymer/Au Nanoparticles (ZnTPP/D-g-PNIPAM/AuNPs) triple hybrid nanosystem was synthesized in aqueous solution as a nanodrug for potential use thermally driven and controlled photodynamic therapy applications. of the has demonstrated excellent stability terms aggregation sedimentation several days after preparation. Optimal concentrations components providing lowest level highest...
Abstract Explosion puffing drying was investigated as potential means for winter jujube. The sample dried by hot air to dehydrate some amount of internal free water prior explosion final moisture less than 7% (wet bases). Physical properties (shrinkage, color, porosity, density, texture, and rehydration ratio) crispy jujube this method were evaluated compared with those convectional alone, freeze-drying combination freezing drying, respectively. comparison showed that exhibited very close...
Lymphoma cells expressing CD5 (CD5+) confer inferior outcome of diffuse large B-cell lymphoma (DLBCL), especially in non-MYC/BCL2 double expressor (non-DE) patients. In tumor microenvironment, CD5+ non-DE revealed increased proportion immunosuppressive M2 macrophages and enhanced pathways related to macrophage activation migration. accordance activation, lipid metabolism was upregulated, including fatty acid uptake oxidation, which supplied energy for polarization activation. Meanwhile, CD36...
Mast cell leukemia is a rare and aggressive disease, predominantly with KIT D816V mutation. With poor response to conventional poly-chemotherapy, mast responded the midostaurin treatment 50% overall rate (ORR), but complete remission approximately 0%. Therefore, potential mechanisms of resistance exact impacts on both gene expression profile microenvironment in vivo are essential for design tailored combination therapy targeting tumor cells microenvironment. Here we report 59-year-old male...