A5059531601- RNA Interference and Gene Delivery
- Nanoparticle-Based Drug Delivery
- Genomics and Phylogenetic Studies
- Monetary Policy and Economic Impact
- Chromosomal and Genetic Variations
- Market Dynamics and Volatility
- Supramolecular Self-Assembly in Materials
- Remote Sensing and Land Use
- Pharmacological Effects of Natural Compounds
- Genetic diversity and population structure
- Photosynthetic Processes and Mechanisms
- Advanced Drug Delivery Systems
- Energy, Environment, and Transportation Policies
- Complex Systems and Time Series Analysis
- Plant biochemistry and biosynthesis
- Advanced biosensing and bioanalysis techniques
- Photoacoustic and Ultrasonic Imaging
- Antioxidant Activity and Oxidative Stress
- Hydrocarbon exploration and reservoir analysis
- Infant Nutrition and Health
- Medicinal Plant Pharmacodynamics Research
- Ultrasound Imaging and Elastography
- CRISPR and Genetic Engineering
- Financial Markets and Investment Strategies
- Bioenergy crop production and management
Fudan University
2013-2024
TianjinSino-German University of Applied Sciences
2023
Satellite Application Center for Ecology and Environment
2023
Beijing Forestry University
2020-2022
Shandong University of Finance and Economics
2022
Shandong Academy of Forestry
2021
Shandong University of Traditional Chinese Medicine
2012-2013
Tianjin University of Traditional Chinese Medicine
2010
Tongji University
2004
Geological Institute
1996
The blood-brain barrier (BBB), which is formed by the brain capillary wall, greatly hinders development of new drugs for brain. Over past decades, among various receptor-mediated endogenous BBB transport systems, strategy using transferrin or anti-transferrin receptor antibodies to facilitate drug delivery system particular interest. However, application large proteins still suffers from drawbacks including synthesis procedure, stability, and immunological response. Here, we explored a B6...
Chemotherapy is an indispensable auxiliary treatment for glioma but highly limited by the existence of both blood-brain barrier (BBB) and tumor (BBTB). The dysfunctional brain blood vessels high interstitial pressure in also greatly hindered accumulation deep penetration chemotherapeutics into glioma. Lactoferrin (Lf), with its receptor overexpressed on endothelial cells cells, was here functionalized to surface poly(ethylene glycol)-poly(lactic acid) nanoparticles mediate BBB/BBTB cell dual...
Populus has a wide ecogeographical range spanning the Northern Hemisphere, and interspecific hybrids are common. tomentosa Carr. is widely distributed cultivated in eastern region of Asia, where it plays multiple important roles forestry, agriculture, conservation, urban horticulture. Reference genomes available for several species, however, our goals were to produce very high quality de novo chromosome-level genome assembly P. that could serve as reference evolutionary ecological studies...
Based on the powerful cell-penetrating ability of low molecular weight protamine (LMWP) and overexpression matrix metalloproteinases in tumor sites, we constructed an activatable (ALMWP) modified it onto surface poly(ethylene glycol)-poly(lactic acid) nanoparticles to develop a "smart" drug delivery system with enhanced permeability for facilitating site-specific targeting anticancer drug. The obtained ALMWP-functionalized (ALMWP-NP) particle size 134.0 ± 4.59 nm zeta potential -34.4 2.7 mV,...
With the outbreak of COVID-19, a large number medical staffs have invested in front line anti-epidemic. Medical protective clothing (MPC) can provide safe environment for wearers to block bacteria and viruses. However, nowadays, thermal performance MPC on market is very poor, resulting extremely low comfort wearer. Some improved MPCs were made materials, which not easy obtain with high cost. lack experimental data based real human body. Therefore, this paper proposed novel reusable PCM...
Flowering is an important link in the life process of angiosperms, and it also sign transformation plants from vegetative to reproductive growth. Although flowering regulation network Arabidopsis well-understood, there has been little research on molecular mechanisms perennial woody plant flower development regulation. Populus tomentosa a unique Chinese poplar species with fast growth, strong ecological adaptability, long lifecycle. However, juvenile phase, which seriously affects its...
Cellulose synthesis is a complex process in plant cells that important for wood processing, pulping, and papermaking. begins with the glycosylation of sitosterol by glycosyltransferase (SGT) to produce sitosterol-glucoside (SG), which acts as guiding primer cellulose production. However, biological functions SGTs Populus tomentosa(P. tomentosa) remain largely unknown. Two full-length PtSGT genes (PtSGT1 PtSGT4) were previously isolated from P. tomentosa characterized. In present study,...
Abstract Forecasting international stock market volatility using the oil risk premium (OVRP) is important for asset allocation and financial management. In previous literature, issue of biased OVRP has not been well addressed. The defined as difference between ex ante risk‐neutral expectation return variation realized variance. This a estimator argued by studies. this paper, we propose new measure OVRP, namely, uncertainty‐driven (UOVRP), in which expected conditional variance futures...
Abstract Populus tomentosa is widely distributed and cultivated in the Northern Central China, where it of great economic ecological importance. However, origin P. remains controversial. Here, we used a PacBio+Hi-C+Illumina strategy to sequence assemble its 740.2 Mb (2n) genome. The assembly accounts for greater than 92.1% 800-megabase genome, comprises 38 chromosomes, contains 59,124 annotated protein-coding genes. Phylogenomic analyses elucidated dynamic genome evolution events among...
Accurate classification of wetland vegetation types is the basis for monitoring and management ecosystems. At present, recognition accuracy based on UAV remote sensing images not high. In this paper, to address problem, 17 feature variables contained in spectrum, spatial geometry texture were firstly selected; then improved JM-Relief F algorithm was used rank, judge select weights constructed variables, remove redundant variables; finally, preferred 8 classified by random forest, support...
We examine seasonality in commodity futures markets using monthly returns for 26 commodities from 1970 through 2022. There are only a few the early years that show half-month and seasonalities. The same-month trading strategy proposed by Keloharju, Linnainmaa, Nyberg (2016) outperformed other-month subperiod of 1990–1999, showing findings Keloharju et al. not robust to different sample periods. then conduct back-testing momentum compare its performance with approach. find significant most...