Jun Chen

ORCID: 0000-0001-8732-6107
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About
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Research Areas
  • Hydrogels: synthesis, properties, applications
  • Advanced Drug Delivery Systems
  • Quantum Dots Synthesis And Properties
  • 3D Printing in Biomedical Research
  • Electrospun Nanofibers in Biomedical Applications
  • Wound Healing and Treatments
  • Advanced biosensing and bioanalysis techniques
  • Electrochemical sensors and biosensors
  • Advanced Chemical Sensor Technologies
  • Nanoplatforms for cancer theranostics
  • Advanced Sensor and Energy Harvesting Materials
  • Advanced Polymer Synthesis and Characterization
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Supramolecular Self-Assembly in Materials
  • Extracellular vesicles in disease
  • Biosensors and Analytical Detection
  • Nanoparticle-Based Drug Delivery
  • Diabetic Foot Ulcer Assessment and Management
  • Tissue Engineering and Regenerative Medicine
  • Advanced Materials and Mechanics
  • Enzyme Production and Characterization
  • Chalcogenide Semiconductor Thin Films
  • Photonic and Optical Devices
  • Conducting polymers and applications
  • Copper-based nanomaterials and applications

Southern Medical University
2013-2025

Nankai University
2006-2025

Janssen (United States)
2025

Guangzhou Institutes of Biomedicine and Health
2023-2025

Shijia Photons (China)
2023-2025

Xianning Central Hospital
2025

Hubei University of Science and Technology
2025

Nanfang Hospital
2025

Chinese University of Hong Kong
2025

Hubei University of Arts and Science
2025

The ability to engineer surface properties of nanocrystals (NCs) is important for various applications, as many the physical and chemical nanoscale materials are strongly affected by chemistry. Here, we report a facile ligand-exchange approach, which enables sequential functionalization phase transfer colloidal NCs while preserving NC size shape. Nitrosonium tetrafluoroborate (NOBF4) used replace original organic ligands attached surface, stabilizing in polar, hydrophilic media such...

10.1021/ja108948z article EN Journal of the American Chemical Society 2010-12-22

We have been interested in the synthesis of hydrogels with fast swelling kinetics and superabsorbent properties. To increase water absorption rate, interconnected pores were introduced to hydrogels. Since pore size dried is order hundreds micrometers, these are called "superporous" Superporous synthesized by crosslinking polymerization various vinyl monomers presence gas bubbles formed chemical reaction acid NaHCO3. The process was optimized capture inside use NaHCO3/acid system allowed easy...

10.1002/(sici)1097-4636(199901)44:1<53::aid-jbm6>3.0.co;2-w article EN Journal of Biomedical Materials Research 1999-01-01

Irregular defects generated by trauma or surgery in orthopaedics practice were usually difficult to be fitted the preformed traditional bone graft substitute. Therefore, injectable hydrogels have attracted an increasing interest for repair because of their fittability and mini-invasivity. However, uncontrollable spreading mechanical failures during its manipulation remain a problem solved. Moreover, order achieve vascularized regeneration, alternatives osteogenic angiogenic growth factors...

10.1016/j.bioactmat.2022.02.011 article EN cc-by-nc-nd Bioactive Materials 2022-02-25

Tissue-like cultured meats of some livestock have successfully been established by different approaches. However, the production a structure similar to fish fillets is still challenging. Here, we develop tissue-like assembly large yellow croaker muscle fibers and adipocytes with 3D-printed gel. Inhibition Tgf-β Notch signals significantly promoted myogenic differentiation piscine satellite cells (PSCs). The mixture gelatin sodium alginate combined p53 inhibitor Yap activator supported PSC...

10.1038/s41538-023-00194-2 article EN cc-by npj Science of Food 2023-05-06

10.1016/s0168-3659(99)00238-2 article EN Journal of Controlled Release 2000-03-01

Endothelium-derived microparticles have recently been described as a new marker of endothelial cell dysfunction. Increased levels circulating documented in inflammatory disorders, diabetes mellitus, and many cardiovascular diseases. Perturbations angiogenesis play an important role the pathogenesis these disorders. We demonstrated previously that isolated (EMPs) impair function vitro, diminishing acetylcholine-induced vasorelaxation nitric oxide production by rat aortic rings simultaneously...

10.1152/ajpheart.00265.2005 article EN AJP Heart and Circulatory Physiology 2005-05-07

Abstract Because of its good biocompatibility and biodegradability, albumins such as bovine serum albumin (BSA) human (HSA) have found a wide range biomedical applications. Herein, we report that glutaraldehyde cross-linked BSA (or HSA) forms novel fluorescent biological hydrogel, exhibiting new green red autofluorescence in vitro vivo without the use any additional labels. UV-vis spectra studies, conjunction with fluorescence studies including emission, excitation synchronous scans,...

10.1038/srep19370 article EN cc-by Scientific Reports 2016-01-27

10.1016/j.polymdegradstab.2009.05.011 article EN Polymer Degradation and Stability 2009-05-28

The healing process of diabetic wounds is typically disordered and prolonged requires both angiogenesis epithelialization. Disruptions the endogenous electric fields (EFs) may lead to cell migration. Electrical stimulation (ES) that mimics EFs a promising method in treating wounds; however, microenvironment facilitates migration convenient means can be used apply ES are also required. Chitosan-Vaseline® gauze (CVG) has been identified facilitate wound healing; it promotes moisture retention...

10.1016/j.bioactmat.2020.08.003 article EN cc-by-nc-nd Bioactive Materials 2020-08-19

Purebred Bamei piglets present problems, including slow growth, respiratory disease, and post-weaning stress. This study investigated the effects of Lactobacillus plantarum QP28-1- Bacillus subtilis QB8-fermented feed supplementation on growth performance, immunity, intestinal microflora from Qinghai, China. A total 48 purebred (25 days; 6.8 ± 0.97 kg) were divided into following four groups for a 28-day diet experiment: basal (CK); containing 10% plantarum-fermented (L); subtilis-fermented...

10.3390/ani14040647 article EN cc-by Animals 2024-02-17

Stimuli-sensitive hydrogels (or smart hydrogels) are that swell or shrink in response to small changes environmental conditions which they placed. While the extent of swelling shrinking may be large, kinetics such is slow, since diffusion water into and out hydrogel a slow process. To obtain fast responses, we have prepared superporous (SPHs) can extremely regardless their dimensions. The orders magnitude faster than expected for nonporous same Water molecules taken up SPHs by capillary...

10.1163/156856200744390 article EN Journal of Biomaterials Science Polymer Edition 2000-01-01

We demonstrated a simple and facile approach to fabricate biocompatible monodisperse hollow microparticles of controlled geometry. The hemispherical, spherical, cubical are obtained by drying multilayer capsules hydrogen-bonded poly(N-vinylpyrrolidone)/tannic acid (PVPON/TA)n. Drying spherical results in hemispherical particles if 15 < n 20. This shape transformation is capsule stiffness, which regulated the layer number, diameter, PVPON molecular weight. Cubical maintaining their...

10.1021/bm4008666 article EN Biomacromolecules 2013-09-24
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